2024
Impact of Synthetic PET Evaluation prior to PET-Guided Functional Modeling in Optimizing Patient Selection for Biology-Guided Radiotherapy
Hicks D, Chen H, Kim J, Tressel L, Wallington D, Becht K, Johung K, Young M, Feghali K, de Jong D, Chen Z, Carlson D, Park H. Impact of Synthetic PET Evaluation prior to PET-Guided Functional Modeling in Optimizing Patient Selection for Biology-Guided Radiotherapy. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: s162-s163. DOI: 10.1016/j.ijrobp.2024.07.2188.Peer-Reviewed Original ResearchPlanning target volumeInternal target volumeBiology-guided radiotherapyStereotactic body radiotherapyGross tumor volumeTarget volumeCT simulationOptimal patient selectionPET evaluationStereotactic body radiotherapy planLung target volumesPatient selectionPTV edgesLung casesBgRTPET-CTTumor sizeTumor volumeRadiotherapyCase 2PET dataLungActivity concentrationsPatientsConsistent with resultsEvaluation of Biology-Guided Radiotherapy (BgRT) in Motion Phantom with Real Patient Breathing Patterns
Chen H, Han D, Draeger E, Zhong W, Lee M, Guan F, Hicks D, Park H, Johung K, Young M, Bal G, Carlson D, Chen Z. Evaluation of Biology-Guided Radiotherapy (BgRT) in Motion Phantom with Real Patient Breathing Patterns. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e107. DOI: 10.1016/j.ijrobp.2024.07.2018.Peer-Reviewed Original ResearchGamma passing ratesBiology-guided radiotherapyPatient's breathing patternMotion phantomPass ratePatient-specific quality assuranceBreathing periodPhantom studyGamma passing criteriaTumor motion managementAssess target coverageQuality assurance phantomBreathing patternDosimetric accuracyConformity indexMotion managementActivity concentrationsHomogeneity indexTarget coverageDelivery accuracyTarget volumeSpherical targetCommissioning dataBgRTPassing criteria
2022
Impact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer
Oh P, Laird J, Johung K. Impact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e197. DOI: 10.1016/j.ijrobp.2022.07.1113.Peer-Reviewed Original ResearchStereotactic body radiotherapyInternal target volumeUnivariate regression analysisGross tumor volumeOverall survivalLocal controlPancreatic cancerPerformance statusSBRT plansTarget volumeCox proportional hazards modelDosimetric parametersAdvanced unresectable diseaseImproved local controlRetrospective cohort studyUse of chemotherapyGood local controlKaplan-Meier methodPancreatic cancer patientsTarget volume sizeProportional hazards modelHigher gross tumor volumeMATERIAL/METHODSComprehensive dosimetric analysisUnresectable disease