2022
Impact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer
Oh P, Laird J, Johung K. Impact of Dosimetric Parameters on Local Control after SBRT for Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e197. DOI: 10.1016/j.ijrobp.2022.07.1113.Peer-Reviewed Original ResearchStereotactic body radiotherapyInternal target volumeUnivariate regression analysisGross tumor volumeOverall survivalLocal controlPancreatic cancerPerformance statusSBRT plansTarget volumeCox proportional hazards modelDosimetric parametersAdvanced unresectable diseaseImproved local controlRetrospective cohort studyUse of chemotherapyGood local controlKaplan-Meier methodPancreatic cancer patientsTarget volume sizeProportional hazards modelHigher gross tumor volumeMATERIAL/METHODSComprehensive dosimetric analysisUnresectable disease
2020
The Utility of Neoadjuvant Radiotherapy after Neoadjuvant Multiagent Chemotherapy in Patients with Localized Pancreatic Cancer
Miccio J, Talcott W, Patel T, Park H, Cecchini M, Salem R, Stein S, Kortmansky J, Lacy J, Johung K, Jethwa K. The Utility of Neoadjuvant Radiotherapy after Neoadjuvant Multiagent Chemotherapy in Patients with Localized Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e31-e32. DOI: 10.1016/j.ijrobp.2020.02.538.Peer-Reviewed Original Research
2018
Chemoradiation after FOLFIRINOX for borderline resectable or locally advanced pancreatic cancer
Mancini BR, Stein S, Lloyd S, Rutter CE, James E, Chang BW, Lacy J, Johung KL. Chemoradiation after FOLFIRINOX for borderline resectable or locally advanced pancreatic cancer. Journal Of Gastrointestinal Oncology 2018, 9: 982-988. PMID: 30603116, PMCID: PMC6286925, DOI: 10.21037/jgo.2018.04.03.Peer-Reviewed Original ResearchDistant metastasis-free survivalAdvanced pancreatic cancerConsolidative chemoradiationOverall survivalLocal controlPancreatic cancerMedian distant metastasis-free survivalCox proportional hazards modelCommon Terminology CriteriaEfficacy of FOLFIRINOXMedian overall survivalMore T4 tumorsMulti-agent chemotherapyR0 surgical resectionUse of FOLFIRINOXMonths of chemotherapyResponse Evaluation CriteriaKaplan-Meier analysisMetastasis-free survivalProportional hazards modelTerminology CriteriaProspective trialRadiographic responseSurgical resectionT3 tumors
2015
Stereotactic Body Radiation Therapy Versus Conventionally Fractionated Radiation Therapy: A Propensity Score Matched Analysis of Survival in Unresected Pancreatic Cancer
Corso C, Park H, Rutter C, Lester-Coll N, Mancini B, Yeboa D, Johung K. Stereotactic Body Radiation Therapy Versus Conventionally Fractionated Radiation Therapy: A Propensity Score Matched Analysis of Survival in Unresected Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: s155-s156. DOI: 10.1016/j.ijrobp.2015.07.370.Peer-Reviewed Original ResearchAddition of radiotherapy to adjuvant chemotherapy is associated with improved overall survival in resected pancreatic adenocarcinoma: An analysis of the National Cancer Data Base
Rutter CE, Park HS, Corso CD, Lester-Coll NH, Mancini BR, Yeboa DN, Johung KL. Addition of radiotherapy to adjuvant chemotherapy is associated with improved overall survival in resected pancreatic adenocarcinoma: An analysis of the National Cancer Data Base. Cancer 2015, 121: 4141-4149. PMID: 26280559, DOI: 10.1002/cncr.29652.Peer-Reviewed Original ResearchConceptsImproved overall survivalNational Cancer Data BaseOverall survivalPancreatic adenocarcinomaAdjuvant chemotherapyR0 resectionR1 resectionPN1 diseaseNational cohortSubset analysisPropensity scoreAddition of radiotherapyMedian radiotherapy doseOutcome of chemotherapyLarge national cohortPT1-3N0CRT groupClinicopathologic characteristicsCRT patientsRandomized comparisonCox regressionRadiotherapy doseOptimal treatmentPancreatic cancerUnivariate analysis