2005
Ventilator-Associated Pneumonia in Injured Patients: Do You Trust Your Gram’s Stain?
Davis KA, Eckert MJ, Reed RL, Esposito TJ, Santaniello JM, Poulakidas S, Luchette FA. Ventilator-Associated Pneumonia in Injured Patients: Do You Trust Your Gram’s Stain? Journal Of Trauma And Acute Care Surgery 2005, 58: 462-467. PMID: 15761337, DOI: 10.1097/01.ta.0000153941.39697.aa.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAnti-Bacterial AgentsBronchoalveolar LavageCross InfectionFemaleGentian VioletGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsHospital MortalityHumansIllinoisLength of StayMaleMiddle AgedMultiple TraumaPatient SelectionPhenazinesPneumonia, BacterialPredictive Value of TestsRespiration, ArtificialRetrospective StudiesSputumTrauma CentersConceptsVentilator-associated pneumoniaGram-positive ventilator-associated pneumoniaGram stainTrauma patientsGram-negative ventilator-associated pneumoniaPredictive valueDiagnosis of VAPPresumptive antibiotic therapyResults of sputumRetrospective chart reviewNegative predictive valuePositive predictive valueChart reviewAntibiotic therapyBAL fluidPresumptive therapyPrevention criteriaGram-positive organismsEarly diagnosisPatientsQuantitative culturesPneumoniaDisease controlNegative organismsCulture data
2004
Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model
Davis KA, Santaniello JM, He LK, Muthu K, Sen S, Jones SB, Gamelli RL, Shankar R. Burn Injury and Pulmonary Sepsis: Development of a Clinically Relevant Model. Journal Of Trauma And Acute Care Surgery 2004, 56: 272-278. PMID: 14960967, DOI: 10.1097/01.ta.0000108995.64133.90.Peer-Reviewed Original ResearchConceptsColony-stimulating factorPulmonary sepsisCytokine tumor necrosisSystemic sepsisInterleukin-6Tumor necrosisProinflammatory cytokine tumor necrosisInflammatory cytokine tumor necrosisAlveolar macrophage releaseBurn/traumaDorsal scald burnGram stainMultiple organ failureDevelopment of pneumoniaGranulocyte-macrophage (GM) CSFFemoral bone marrow cellsEnd-organ responseIsolated alveolar macrophagesPositive tissue culturesPseudomonas aeruginosaWhole lung tissueMale B6D2F1 miceTissue Gram stainMacrophage colony-stimulating factorBone marrow cells