2022
Ankle- and Toe-Brachial Index for Peripheral Artery Disease Identification: Unlocking Clinical Data Through Novel Methods
Friberg JE, Qazi AH, Boyle B, Franciscus C, Vaughan-Sarrazin M, Westerman D, Patterson OV, Parr SK, Matheny ME, Arya S, Smolderen KG, Lund BC, Gobbel GT, Girotra S. Ankle- and Toe-Brachial Index for Peripheral Artery Disease Identification: Unlocking Clinical Data Through Novel Methods. Circulation Cardiovascular Interventions 2022, 15: e011092. PMID: 35176872, PMCID: PMC10807980, DOI: 10.1161/circinterventions.121.011092.Peer-Reviewed Original ResearchMeSH KeywordsAnkleAnkle Brachial IndexHumansLower ExtremityPeripheral Arterial DiseasePredictive Value of TestsTreatment OutcomeConceptsPeripheral artery diseaseAnkle-brachial indexToe-brachial indexElectronic health recordsABI testingVeterans Affairs electronic health recordsHealth recordsStructured chart reviewVeterans Affairs facilitiesPositive predictive valuePAD patientsChart reviewArtery diseaseClinical dataClinical impactHigh prevalenceBilling codesSeparate cohortPredictive valuePatientsClinical expertsPAD researchRandom sampleLateralityReport
2020
Level of disease and association with health status in patients presenting with claudication from the PORTRAIT registry
Vogel TR, Braet DJ, Kruse RL, Bath J, Wang J, Gosch K, Smolderen KG. Level of disease and association with health status in patients presenting with claudication from the PORTRAIT registry. Journal Of Vascular Surgery 2020, 72: 2017-2026. PMID: 32325227, DOI: 10.1016/j.jvs.2020.03.042.Peer-Reviewed Original ResearchMeSH KeywordsAgedFemaleFunctional StatusHealth Status IndicatorsHumansIntermittent ClaudicationMaleMiddle AgedPatient SatisfactionPeripheral Arterial DiseasePredictive Value of TestsQuality of LifeRegistriesRetrospective StudiesSeverity of Illness IndexSurveys and QuestionnairesTime FactorsTreatment OutcomeConceptsPeripheral artery diseasePAQ summary scorePeripheral Artery QuestionnaireQuality of lifeAnkle-brachial indexMultilevel diseaseAortoiliac diseaseHealth statusAnatomic levelSummary scoresMedical managementHigh ankle-brachial indexFemoral-popliteal diseaseTreatment of aortoiliacChronic kidney diseaseHistory of diabetesPAQ scoresPeripheral arterial diseaseOverall health statusSimilar health statusHealth status informationStudent's t-testLevel of diseaseRepeated-measures analysisInfrapopliteal disease
2019
Ankle-brachial index in patients with intermittent claudication is a poor indicator of patient-centered and clinician-based evaluations of functional status
Johnston AL, Vemulapalli S, Gosch KL, Aronow HD, Abbott JD, Patel MR, Smolderen KG, Shishebor M, Spertus JA, Jones WS. Ankle-brachial index in patients with intermittent claudication is a poor indicator of patient-centered and clinician-based evaluations of functional status. Journal Of Vascular Surgery 2019, 69: 906-912. PMID: 30626552, DOI: 10.1016/j.jvs.2018.07.039.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnkle Brachial IndexAustraliaCost of IllnessFemaleHealth StatusHemodynamicsHumansIntermittent ClaudicationMaleMiddle AgedNetherlandsPatient Reported Outcome MeasuresPeripheral Arterial DiseasePredictive Value of TestsProspective StudiesQuality of LifeRegistriesSeverity of Illness IndexUnited StatesConceptsAnkle-brachial indexPeripheral artery diseasePeripheral Artery QuestionnaireIntermittent claudicationRutherford classificationABI valuesPAQ scoresArtery diseaseImpact of PADHealth statusMean ankle-brachial indexPAD-specific health statusSevere peripheral artery diseasePAQ summary scoreStudy of patientsQuality of lifeHealth status assessmentRutherford classNew onsetPatient's symptomsHemodynamic assessmentLife scoresFunctional statusPatients' perceptionsInternational cohort
2018
Associations of exercise ankle–brachial index, pain-free walking distance and maximum walking distance with the Peripheral Artery Questionnaire: Finding from the PORTRAIT PAD Registry
Hammad TA, Smolderen KG, Spertus JA, Jones PG, Shishehbor MH. Associations of exercise ankle–brachial index, pain-free walking distance and maximum walking distance with the Peripheral Artery Questionnaire: Finding from the PORTRAIT PAD Registry. Vascular Medicine 2018, 24: 32-40. PMID: 29992849, DOI: 10.1177/1358863x18785026.Peer-Reviewed Original ResearchConceptsPain-free walking distancePeripheral artery diseaseMaximum walking distancePeripheral Artery QuestionnairePhysical limitation scoreWalking distancePatient factorsLimitation scoresImpact of PADAnkle-brachial index (ABI) testExercise ankle-brachial indexOnset of claudicationPost-exercise ABIAnkle-brachial indexQuality of lifeHierarchical logistic regression modelsLogistic regression modelsPORTRAIT registryArtery diseasePatient's symptomsPatient functioningABI testingSummary scoresHealth statusSymptomsEffectiveness of a comprehensive interactive eHealth intervention on patient-reported and clinical outcomes in patients with an implantable cardioverter defibrillator [ACQUIRE-ICD trial]: study protocol of a national Danish randomised controlled trial
Pedersen SS, Skovbakke SJ, Wiil UK, Schmidt T, dePont Christensen R, Brandt CJ, Sørensen J, Vinther M, Larroudé CE, Melchior TM, Riahi S, Smolderen KGE, Spertus JA, Johansen JB, Nielsen JC. Effectiveness of a comprehensive interactive eHealth intervention on patient-reported and clinical outcomes in patients with an implantable cardioverter defibrillator [ACQUIRE-ICD trial]: study protocol of a national Danish randomised controlled trial. BMC Cardiovascular Disorders 2018, 18: 136. PMID: 29969990, PMCID: PMC6029360, DOI: 10.1186/s12872-018-0872-7.Peer-Reviewed Original ResearchMeSH KeywordsDefibrillators, ImplantableDenmarkElectric CountershockHealth StatusHeart FailureHumansMental HealthMulticenter Studies as TopicPatient Reported Outcome MeasuresPredictive Value of TestsProspective StudiesQuality of LifeRandomized Controlled Trials as TopicRemote Sensing TechnologyRisk FactorsTelemedicineTelemetryTime FactorsTreatment OutcomeConceptsImplantable cardioverter defibrillatorQuality of lifeEHealth interventionsUsual careClinical outcomesCardioverter defibrillatorFlorida Patient Acceptance SurveyCardiac synchronization therapyFirst ICD therapyTrial registrationThe trialCare innovationsManagement of patientsPatient-reported outcomesFirst‐time implantable cardioverter defibrillatorsMonitoring of symptomsQuality of carePatient-physician interactionFirst hospitalisationICD therapyPrimary endpointSecondary endpointsMore patientsSuperiority trialDisease management approachClinical effectiveness
2016
Health Status Outcomes in Patients With Acute Myocardial Infarction After Rehospitalization
Shore S, Smolderen KG, Kennedy KF, Jones PG, Arnold SV, Cohen DJ, Stolker JM, Zhao Z, Wang TY, Ho PM, Spertus JA. Health Status Outcomes in Patients With Acute Myocardial Infarction After Rehospitalization. Circulation Cardiovascular Quality And Outcomes 2016, 9: 777-784. PMID: 27780850, PMCID: PMC5794496, DOI: 10.1161/circoutcomes.116.002883.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina, UnstableFemaleHealth StatusHealth Status IndicatorsHumansLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionMyocardial RevascularizationPatient ReadmissionPredictive Value of TestsPropensity ScoreProspective StudiesQuality of LifeRegistriesRisk FactorsSurveys and QuestionnairesTime FactorsUnited StatesConceptsAcute myocardial infarctionComposite end pointUnplanned revascularizationUnstable anginaMyocardial infarctionHealth statusEuroQol-5D visual analogue scaleVisual analog scale scoreEnd pointUnplanned coronary revascularizationPropensity-matched cohortAnalog scale scoreSeattle Angina QuestionnaireVisual analog scaleHealth status outcomesWorse health statusAngina QuestionnaireCoronary revascularizationRehospitalization ratesAnalog scaleMean ageSuch readmissionsQuestionnaire domainsClinical trialsRehospitalization
2015
Long‐Term Prognostic Risk in Lower Extremity Peripheral Arterial Disease as a Function of the Number of Peripheral Arterial Lesions
Smolderen KG, van Zitteren M, Jones PG, Spertus JA, Heyligers JM, Nooren MJ, Vriens PW, Denollet J. Long‐Term Prognostic Risk in Lower Extremity Peripheral Arterial Disease as a Function of the Number of Peripheral Arterial Lesions. Journal Of The American Heart Association 2015, 4: e001823. PMID: 26504149, PMCID: PMC4845133, DOI: 10.1161/jaha.115.001823.Peer-Reviewed Original ResearchMeSH KeywordsAgedArteriesChi-Square DistributionDisease ProgressionFemaleHumansKaplan-Meier EstimateLower ExtremityMaleMiddle AgedMultivariate AnalysisNetherlandsPeripheral Arterial DiseasePredictive Value of TestsPrognosisProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsUltrasonography, Doppler, DuplexConceptsLower extremity lesionsPeripheral artery diseasePAD patientsAdverse prognosisExtremity lesionsLower Extremity Peripheral Arterial DiseaseSimple risk stratification toolDuplex ultrasound testingPeripheral arterial lesionsClinical risk factorsPeripheral arterial diseaseFirst adverse eventGreater disease burdenLong-term prognosisRisk stratification toolPAD diagnosisAdverse eventsProspective cohortArtery diseaseArterial diseaseArterial lesionsPrognostic riskDisease burdenIndependent associationRisk factorsOne Year Health Status Benefits Following Treatment for New Onset or Exacerbation of Peripheral Arterial Disease Symptoms: The Importance of Patients' Baseline Health Status
van Zitteren M, Denollet J, Heyligers JM, Elshof JW, Nooren MJ, Burger DH, de Fijter WM, Vriens PW, Smolderen KG. One Year Health Status Benefits Following Treatment for New Onset or Exacerbation of Peripheral Arterial Disease Symptoms: The Importance of Patients' Baseline Health Status. European Journal Of Vascular And Endovascular Surgery 2015, 50: 213-222. PMID: 26036809, DOI: 10.1016/j.ejvs.2015.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisease ProgressionFemaleHealth StatusHealth Status IndicatorsHumansLinear ModelsMaleMental HealthMiddle AgedNetherlandsPeripheral Arterial DiseasePredictive Value of TestsPropensity ScoreProspective StudiesRecovery of FunctionRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexConceptsHealth status scoresPeripheral arterial diseaseHealth status gainsBaseline health statusInvasive treatmentStatus scoreHealth statusPatient's baseline health statusPeripheral arterial disease symptomsHealth status levelsHealth status outcomesNew onsetPAD symptomsVascular clinicArterial diseaseHighest quartilePCS scoresInvasive strategyTreatment strategiesClinical informationStatus outcomesPatientsLinear regression analysisChange scoresExacerbation
2014
Determinants of invasive treatment in lower extremity peripheral arterial disease
van Zitteren M, Vriens PW, Burger DH, de Fijter WM, Gerritsen GP, Heyligers JM, Nooren MJ, Smolderen KG. Determinants of invasive treatment in lower extremity peripheral arterial disease. Journal Of Vascular Surgery 2014, 59: 400-408.e2. PMID: 24461863, DOI: 10.1016/j.jvs.2013.08.045.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnkle Brachial IndexChi-Square DistributionDecision Support TechniquesEndovascular ProceduresFemaleHealth StatusHumansLower ExtremityMaleMiddle AgedNetherlandsOdds RatioPatient SelectionPeripheral Arterial DiseasePredictive Value of TestsProspective StudiesReferral and ConsultationRisk FactorsTreatment OutcomeUltrasonography, Doppler, DuplexVascular Surgical ProceduresConceptsPeripheral arterial diseaseLower extremity peripheral arterial diseasePhysical component scaleInvasive treatmentLesion locationHealth statusArterial diseaseTreatment referralSymptomatic lower extremity peripheral arterial diseaseProspective observational cohort studyVascular surgery outpatient clinicProximal lesion locationAnkle-brachial indexObservational cohort studySurgery outpatient clinicShort Form-12Poor health statusPatients' health statusPoisson regression analysisPAD diagnosisCohort studyPAD symptomsIndependent predictorsAmbulatory patientsForm-12
2011
Accuracy and Prognostic Value of American Heart Association–Recommended Depression Screening in Patients With Coronary Heart Disease
Elderon L, Smolderen KG, Na B, Whooley MA. Accuracy and Prognostic Value of American Heart Association–Recommended Depression Screening in Patients With Coronary Heart Disease. Circulation Cardiovascular Quality And Outcomes 2011, 4: 533-540. PMID: 21862720, DOI: 10.1161/circoutcomes.110.960302.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmerican Heart AssociationComorbidityCoronary DiseaseDepressionDepressive Disorder, MajorDiagnostic Tests, RoutineFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionPredictive Value of TestsPrognosisRiskSensitivity and SpecificitySurveys and QuestionnairesSurvival AnalysisUnited StatesConceptsCoronary heart diseaseAmerican Heart AssociationStable coronary heart diseasePatient Health QuestionnaireMajor depressive disorderHeart diseaseCardiovascular eventsPrognostic valueHeart AssociationDepressive disorderHealth QuestionnaireHigh-density lipoprotein levelsDepression screening protocolSubsequent cardiovascular eventsAdverse cardiovascular outcomesBody mass indexGold standard interviewCardiovascular outcomesIdentifies patientsHeart failureScreening methodLipoprotein levelsMass indexDepression screeningMyocardial infarction
2009
The Association of Cognitive and Somatic Depressive Symptoms With Depression Recognition and Outcomes After Myocardial Infarction
Smolderen KG, Spertus JA, Reid KJ, Buchanan DM, Krumholz HM, Denollet J, Vaccarino V, Chan PS. The Association of Cognitive and Somatic Depressive Symptoms With Depression Recognition and Outcomes After Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2009, 2: 328-337. PMID: 20031858, PMCID: PMC2779543, DOI: 10.1161/circoutcomes.109.868588.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCognitive depressive symptomsSomatic depressive symptomsDepressive symptomsSomatic symptomsAMI patientsMyocardial infarctionCognitive symptomsUnadjusted Cox regression analysisPatient Health Questionnaire scoresDepression recognitionLong-term prognosisCox regression analysisLong-term outcomesRecognition of depressionAssociation of CognitiveCause mortalityCause rehospitalizationIndex hospitalizationMultivariable adjustmentAMI registrySymptom scoresClinical recognitionIndependent associationMedical recordsPreoperative Cardiac Risk Index Predicts Long-term Mortality and Health Status
Hoeks SE, Reimer W, van Gestel YR, Smolderen KG, Verhagen H, van Domburg RT, van Urk H, Poldermans D. Preoperative Cardiac Risk Index Predicts Long-term Mortality and Health Status. The American Journal Of Medicine 2009, 122: 559-565. PMID: 19376487, DOI: 10.1016/j.amjmed.2008.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCerebrovascular DisordersConfidence IntervalsData CollectionDiabetes Mellitus, Type 1FemaleFollow-Up StudiesHealth StatusHealth SurveysHumansMaleMiddle AgedNetherlandsOdds RatioPerioperative CarePeripheral Vascular DiseasesPredictive Value of TestsPreoperative CarePrognosisRegression AnalysisRenal InsufficiencyRisk AdjustmentRisk AssessmentRisk FactorsSurveys and QuestionnairesSurvival AnalysisVascular Surgical ProceduresConceptsPeripheral Artery QuestionnaireImpaired health statusPeripheral arterial disease patientsArterial disease patientsInsulin-dependent diabetesLate mortalityPrognostic factorsHealth statusVascular surgeryRenal insufficiencyCerebrovascular diseaseDisease patientsDisease-specific Peripheral Artery QuestionnaireLong-term health statusPAQ summary scorePerioperative cardiac riskCardiac risk factorsCardiac Risk IndexLong-term mortalityPeripheral arterial diseaseImportant prognostic factorIndependent prognostic factorIschemic heart diseaseMultivariable regression analysisRisk index score
2008
Clinical validity of a disease-specific health status questionnaire: The Peripheral Artery Questionnaire
Hoeks SE, Smolderen KG, Reimer W, Verhagen HJ, Spertus JA, Poldermans D. Clinical validity of a disease-specific health status questionnaire: The Peripheral Artery Questionnaire. Journal Of Vascular Surgery 2008, 49: 371-377. PMID: 19028064, DOI: 10.1016/j.jvs.2008.08.089.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisability EvaluationFactor Analysis, StatisticalFemaleHealth Status IndicatorsHumansIntermittent ClaudicationMaleNetherlandsPain MeasurementPatient SatisfactionPeripheral Arterial DiseasePredictive Value of TestsPsychometricsRecovery of FunctionReproducibility of ResultsRetrospective StudiesSensitivity and SpecificitySeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeVascular Surgical ProceduresWalkingConceptsPeripheral Artery QuestionnairePeripheral arterial diseaseDisease-specific Peripheral Artery QuestionnaireClear dose-response relationPAQ summary scoreDose-response relationClinical indicesClinical validitySummary scoresPAD patientsEQ-VASEQ-5DHealth statusLee Cardiac Risk IndexSymptomatic peripheral arterial diseaseEuroQol visual analogue scaleBaseline clinical indicesConsecutive PAD patientsGeneric EQ-5DSeverity of claudicationCardiac Risk IndexDisease-specific health status questionnaireEQ-5D indexHealth Status QuestionnairePatient-centered outcomes