2024
Impact of comorbid opioid use disorder and major depressive disorder on healthcare utilization outcomes in patients with peripheral artery disease: A National Readmission Database analysis
Amenyedor K, Lee M, Algara M, Siddiqui W, Hardt M, Romain G, Mena-Hurtado C, Smolderen K. Impact of comorbid opioid use disorder and major depressive disorder on healthcare utilization outcomes in patients with peripheral artery disease: A National Readmission Database analysis. Vascular Medicine 2024, 29: 163-171. PMID: 38391134, DOI: 10.1177/1358863x241228540.Peer-Reviewed Original ResearchComorbid opioid use disorderOpioid use disorderPeripheral arterial diseaseDepressive disorderUse disorderArtery diseaseHealthcare utilization outcomesICD-9/10 diagnosis codesPain management strategiesMultivariate logistic regression modelNational Readmission DatabaseHierarchical multivariable logistic regression modelsLength of stayLogistic regression modelsMDDMedian stayPrimary outcomeHighest median costReadmissions DatabasePatientsMedian costStudy populationUtilization outcomesWeighted admissionsDiagnosis codes
2023
In-home Visits and Subsequent Health Outcomes in Medicare Advantage Beneficiaries With Coronary Artery Disease, Diabetes, Hypertension, and Depression
Smolderen K, Heath K, Ameli O, Spencer D, Natwick T, Musich S, Miedico T, Mena-Hurtado C. In-home Visits and Subsequent Health Outcomes in Medicare Advantage Beneficiaries With Coronary Artery Disease, Diabetes, Hypertension, and Depression. Medical Care 2023, 61: 366-376. PMID: 37167558, DOI: 10.1097/mlr.0000000000001850.Peer-Reviewed Original ResearchConceptsPrimary care visitsCoronary artery diseaseMajor adverse cardiovascular eventsFirst primary care visitAdverse cardiovascular eventsCare visitsWait-list control groupHome visitsArtery diseaseList control groupControl groupCardiovascular eventsCare metricsOptum Labs Data WarehouseHigh-morbidity conditionsMedicare Advantage populationInpatient care episodesMedicare Advantage beneficiariesRetrospective data analysisSubsequent health outcomesIndex dateSecondary outcomesEmergency visitsPrimary outcomeInpatient stayCommunity distress and risk of adverse outcomes after peripheral vascular intervention
Schenck C, Strand E, Smolderen K, Romain G, Nagpal S, Cleman J, Blume P, Mena-Hurtado C. Community distress and risk of adverse outcomes after peripheral vascular intervention. Journal Of Vascular Surgery 2023, 78: 166-174.e3. PMID: 36944389, PMCID: PMC11146282, DOI: 10.1016/j.jvs.2023.03.027.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsDistressed Communities IndexMajor amputationRisk of mortalityAdverse outcomesVascular interventionsVascular Quality Initiative databaseDCI scoresCommunity distressCox regression modelTime-dependent receiverCharacteristic curve analysisClinical characteristicsFinal cohortPrimary outcomeClinical outcomesCardiovascular diseasePatientsAmputationZip code dataMortalityRisk categoriesCurve analysisInitiative databaseOutcomes
2021
Contemporary Trends in Hospital Admissions and Outcomes in Patients With Critical Limb Ischemia
Anantha-Narayanan M, Doshi RP, Patel K, Sheikh AB, Llanos-Chea F, Abbott JD, Shishehbor MH, Guzman RJ, Hiatt WR, Duval S, Mena-Hurtado C, Smolderen KG. Contemporary Trends in Hospital Admissions and Outcomes in Patients With Critical Limb Ischemia. Circulation Cardiovascular Quality And Outcomes 2021, 14: e007539. PMID: 33541110, DOI: 10.1161/circoutcomes.120.007539.Peer-Reviewed Original ResearchConceptsLength of stayMajor amputationCost of hospitalizationHospital mortalitySurgical interventionEndovascular interventionBlack raceHigh-risk patient profileNational Inpatient Sample dataHigher major amputationMore endovascular interventionsRisk patient profileCritical limb ischemiaOpen surgical interventionMultivariable regression analysisHierarchical multivariable regression analysisCLI cohortHospital admissionLimb ischemiaPrimary outcomeRevascularization proceduresSecondary outcomesAtherosclerotic diseaseMale sexFemale sex