2021
Salivary cytokine cluster moderates the association between caregivers perceived stress and emotional functioning in youth
Parent C, Pokhvisneva I, de Mendonça Filho EJ, O'Donnell KJ, Meaney MJ, Kee MZL, Thng G, Wing H, Adler NE, Keeton V, Pantell MS, Hessler D, Gottlieb LM, Silveira PP. Salivary cytokine cluster moderates the association between caregivers perceived stress and emotional functioning in youth. Brain Behavior And Immunity 2021, 94: 125-137. PMID: 33662503, DOI: 10.1016/j.bbi.2021.02.025.Peer-Reviewed Original ResearchConceptsCaregivers' perceived stressIL-1βIL-6Cytokine clusterChild Behavior ChecklistEmotional functioningIL-8 cytokine levelsChild emotional functioningPediatric clinic visitsProspective birth cohortHyperactivity problemsEarly life stressPerceived stressPotential intergenerational effectsUCSF cohortSystemic inflammationClinic visitsCytokine levelsInflammation levelsSalivary levelsAttention Deficit Hyperactivity ProblemsIL-8Pediatric QualityLife InventoryBirth cohort
2016
Stress hormones and posttraumatic stress symptoms following paediatric critical illness: an exploratory study
Als LC, Picouto MD, O’Donnell K, Nadel S, Cooper M, Pierce CM, Kramer T, Glover VAS, Garralda ME. Stress hormones and posttraumatic stress symptoms following paediatric critical illness: an exploratory study. European Child & Adolescent Psychiatry 2016, 26: 511-519. PMID: 27995329, PMCID: PMC5394132, DOI: 10.1007/s00787-016-0933-3.Peer-Reviewed Original ResearchConceptsPediatric critical illnessPosttraumatic stress symptomsCritical illnessHealthy controlsEvening cortisolCortisol concentrationsExploratory case-control studyStress symptomsModest independent predictorCase-control studyEvening cortisol concentrationsBasal cortisol concentrationsPICU admissionPICU groupIndependent predictorsSeptic illnessSymptoms of PTSDSignificant positive associationStudy of childrenPrimary analysisMultivariate analysisSecondary analysisCortisol regulationConsecutive weekdaysStress hormones
2014
Cortisol awakening response and subsequent depression: prospective longitudinal study
Carnegie R, Araya R, Ben-Shlomo Y, Glover V, O'Connor TG, O'Donnell KJ, Pearson R, Lewis G. Cortisol awakening response and subsequent depression: prospective longitudinal study. The British Journal Of Psychiatry 2014, 204: 137-143. PMID: 24311550, PMCID: PMC3909839, DOI: 10.1192/bjp.bp.113.126250.Peer-Reviewed Original ResearchConceptsCortisol awakening responseSubsequent depressionSalivary cortisolAwakening responseOdds ratioTime pointsICD-10 criteriaLongitudinal studyProspective longitudinal studyAvon Longitudinal StudyShort-term riskSubsequent depressive illnessLarge population cohortAdrenal functionDepressive illnessClinical significancePopulation cohortElevated cortisolCortisolLogistic regressionCortisol measuresStress reactivityDepressionDiurnal dropAssociation
2013
Prenatal maternal mood is associated with altered diurnal cortisol in adolescence
O’Donnell K, Glover V, Jenkins J, Browne D, Ben-Shlomo Y, Golding J, O’Connor T. Prenatal maternal mood is associated with altered diurnal cortisol in adolescence. Psychoneuroendocrinology 2013, 38: 1630-1638. PMID: 23433748, PMCID: PMC3695029, DOI: 10.1016/j.psyneuen.2013.01.008.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAffectAnxietyCircadian RhythmDepressionFemaleFollow-Up StudiesHumansHydrocortisoneHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsSalivaSampling StudiesSecretory RateSeverity of Illness IndexSocioeconomic FactorsWakefulnessConceptsPrenatal anxietyDiurnal cortisolMaternal postnatal anxietyMaternal prenatal anxietyPrenatal maternal moodMultilevel model analysisAdolescent cortisolCortisol awakening responsePostnatal covariatesProspective longitudinal studyFlatter diurnal slopeCommunity samplePrenatal moodPostnatal anxietyMaternal moodCortisol samplesMaternal depressionAnxietyAwakening responseLongitudinal studyDiurnal slopePersisting effectPrenatal stressAnimal workALSPAC cohort
2010
Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy
King NM, Chambers J, O’Donnell K, Jayaweera SR, Williamson C, Glover VA. Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy. Archives Of Women's Mental Health 2010, 13: 339-345. PMID: 20101421, DOI: 10.1007/s00737-009-0139-5.Peer-Reviewed Original ResearchConceptsMedical disordersSaliva cortisolDiurnal saliva samplesAdverse pregnancy outcomesHigher EPDS scoresSubgroup of womenExtra psychological supportSelf-rating questionnaireVs. 35.2Antenatal womenHyperemesis gravidarumPregnancy outcomesEPDS scoresPregnant womenVs. 5.9Neurodevelopmental problemsCortisol levelsHealth professionalsPregnancySaliva samplesDisorder groupElevated levelsPsychological supportWomenDisorders
2009
Salivary α-amylase stability, diurnal profile and lack of response to the cold hand test in young women
O'Donnell K, Kammerer M, O'Reilly R, Taylor A, Glover V. Salivary α-amylase stability, diurnal profile and lack of response to the cold hand test in young women. Stress 2009, 12: 549-554. PMID: 19658030, DOI: 10.3109/10253890902822664.Peer-Reviewed Original ResearchConceptsCold hand testSalivary alpha-amylaseLack of responseSympathetic nervous systemHand TestSalivary alpha-amylase responseSalivary cortisol measurementsAlpha-amylase responsesSympathetic stimulationSympathetic systemAdrenocortical axisSympathetic regulationNervous systemAlpha-amylaseCortisol measurementsNon-invasive studyYoung womenCortisolDiurnal profileStress testResponseSecretion