2022
Attachment insecurity and the biological embedding of reproductive strategies: Investigating the role of cellular aging
Bolhuis E, Belsky J, Frankenhuis WE, Shalev I, Hastings WJ, Tollenaar MS, O'Donnell KJ, McGill MG, Pokhvisneva I, Lin DTS, MacIsaac JL, Kobor MS, de Weerth C, Beijers R. Attachment insecurity and the biological embedding of reproductive strategies: Investigating the role of cellular aging. Biological Psychology 2022, 175: 108446. PMID: 36272562, DOI: 10.1016/j.biopsycho.2022.108446.Peer-Reviewed Original Research
2021
Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife
Shenk CE, Felt JM, Ram N, O'Donnell KJ, Sliwinski MJ, Pokhvisneva I, Benson L, Meaney MJ, Putnam FW, Noll JG. Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife. Psychoneuroendocrinology 2021, 136: 105606. PMID: 34896740, PMCID: PMC8724404, DOI: 10.1016/j.psyneuen.2021.105606.Peer-Reviewed Original ResearchConceptsEarly life adversityEpigenetic age accelerationChildhood sexual abuseCortisol trajectoriesLife adversityAge accelerationCortisol concentrationsBiological embedding modelProspective cohort studyPeak cortisol levelsHPA axis activitySubstantiated childhood sexual abuseEarly ageCohort studyAdulthood healthHPA axisAdrenal axisCortisol secretionCsA exposureCortisol levelsPotential indicationsSexual abuseMultiple biological systemsSubsequent occasionsBiological embedding
2019
Biological embedding of experience: A primer on epigenetics
Aristizabal MJ, Anreiter I, Halldorsdottir T, Odgers CL, McDade TW, Goldenberg A, Mostafavi S, Kobor MS, Binder EB, Sokolowski MB, O'Donnell KJ. Biological embedding of experience: A primer on epigenetics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 117: 23261-23269. PMID: 31624126, PMCID: PMC7519272, DOI: 10.1073/pnas.1820838116.BooksConceptsEpigenetic mechanismsSpecific epigenetic mechanismsEpigenetic landscapeEpigenome editingDNA sequencesBiological embeddingGene expressionBiological processesCell typesComparative animalHuman longitudinal studiesMolecular profilingPotential roleCorrelative dataEpigenomeGenomeRecent advancesEpigeneticsEditingProfilingCausal dataPrimersMechanismSequenceExpression