Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits
Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature 2002, 415: 793-798. PMID: 11823786, DOI: 10.1038/nature715.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalciumCations, DivalentCentral Nervous SystemCloning, MolecularElectrophysiologyGlutamic AcidGlycineImmunohistochemistryIn Situ HybridizationIon TransportMagnesiumMolecular Sequence DataN-MethylaspartateNeuronsOocytesProtein SubunitsRatsReceptors, GlycineReceptors, N-Methyl-D-AspartateRNA, MessengerSequence HomologySerineSubstrate SpecificityXenopus laevisConceptsExcitatory glycine receptorsGlycine receptorsN-methyl-D-aspartate (NMDA) subtypeD-serineCentral nervous systemNMDA receptor subunitsImpermeable cation channelsVoltage-dependent inhibitionBursts of firingMK-801Inhibitory neurotransmitterMotor neuronsGlutamate receptorsCerebrocortical neuronsCompetitive antagonistNervous systemDual agonistsNMDARNMDAR familyReceptor subunitsNeuronal developmentPathological processesCation channelsReceptorsNR3A