Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line.
Nillni E, Sevarino K, Jackson I. Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line. Endocrinology 1993, 132: 1260-70. PMID: 8440187, DOI: 10.1210/endo.132.3.8440187.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBlotting, WesternElectrophoresis, Polyacrylamide GelKineticsMiceModels, GeneticMolecular Sequence DataMolecular WeightPeptide FragmentsPituitary NeoplasmsProtein PrecursorsProtein Processing, Post-TranslationalPyrrolidonecarboxylic AcidThyrotropin-Releasing HormoneTransfectionTrypsinTumor Cells, CulturedProcessing of proTRH to its intermediate products occurs before the packing into secretory granules of transfected AtT20 cells.
Nillni E, Sevarino K, Jackson I. Processing of proTRH to its intermediate products occurs before the packing into secretory granules of transfected AtT20 cells. Endocrinology 1993, 132: 1271-7. PMID: 8440188, DOI: 10.1210/endo.132.3.8440188.Peer-Reviewed Original Research