1996
Export of Proteins from Mitochondria
Poyton R, Sevarino K, McKee E, Duhl D, Cameron V, Goehring B. Export of Proteins from Mitochondria. Advances In Molecular And Cell Biology 1996, 17: 247-280. DOI: 10.1016/s1569-2558(09)60017-5.Peer-Reviewed Original ResearchNuclear gene productsGene productsIntermembrane spaceInner membraneMitochondrial matrixMembrane coExport of proteinsInner membrane spaceConservative sortingImport pathwayProtein exportLeader peptideLines of evidenceMembrane spaceCytosolProteinMitochondriaPathwayTransport pathwaysPreproteinsMembraneDirect evidenceYeastExportProtease
1989
Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity
Sevarino K, Stork P, Ventimiglia R, Mandel G, Goodman R. Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity. Cell 1989, 57: 11-19. PMID: 2564811, DOI: 10.1016/0092-8674(89)90167-0.Peer-Reviewed Original ResearchConceptsEndocrine cell linesRat preprosomatostatinCarboxy-terminal thirdDistinct cell typesAmino-terminal sequenceCell linesHybrid proteinLeader sequenceIntracellular targetingRegulated pathwayPreprosomatostatin 1Cellular factorsExpression vectorCell typesPattern of processingProcessing siteBioactive peptidesAnglerfish isletsSequenceDifferential processingPeptidesProteinResiduesPathwayHigh levels
1981
54 USE OF AN OPTIMIZED MITOCHONDRIAL PROTEIN SYNTHETIC SYSTEM TO CHARACTERIZE A PRECURSOR TO SUBUNIT II OF CYTOCHROME C OXIDASE
McKee E, Sevarino K, Bellus G, Poyton R. 54 USE OF AN OPTIMIZED MITOCHONDRIAL PROTEIN SYNTHETIC SYSTEM TO CHARACTERIZE A PRECURSOR TO SUBUNIT II OF CYTOCHROME C OXIDASE. 1981, 357-362. DOI: 10.1016/b978-0-08-025382-4.50059-9.Peer-Reviewed Original ResearchProtein synthetic systemCytochrome c oxidaseC oxidaseProtein synthesisMitochondrial translation productsCytoplasmic regulatory proteinsMaximal protein synthesisYeast mitochondriaCytoplasmic proteinsTranslation productsRegulatory proteinsSynthetic systemsMitochondriaProteinNucleotide concentrationsOxidaseSaccharomycesVivoPolypeptideOsmotic pressurePrevious studiesPrecursors