Cocaine Regulation of Brain Preprothyrotropin‐Releasing Hormone mRNA
Sevarino K, Primus R. Cocaine Regulation of Brain Preprothyrotropin‐Releasing Hormone mRNA. Journal Of Neurochemistry 1993, 60: 1151-1154. PMID: 8436966, DOI: 10.1111/j.1471-4159.1993.tb03267.x.Peer-Reviewed Original ResearchConceptsThyrotropin-releasing hormoneCocaine treatmentNucleus accumbensCocaine actionSolution hybridization RNase protectionMRNA levelsRat brain regionsChronic cocaine treatmentAcute cocaine treatmentPreclinical evidenceExtrahypothalamic regionsCocaine withdrawalMin postinjectionH postinjectionPrepro-TRHBrain regionsCocaine regulationCocaine reinforcementAmygdalaThalamusTRH precursorHippocampusHormone mRNASignificant decreaseRNase protection