Biosynthesis of thyrotropin-releasing hormone by a rat medullary thyroid carcinoma cell line.
Sevarino K, Wu P, Jackson I, Roos B, Mandel G, Goodman R. Biosynthesis of thyrotropin-releasing hormone by a rat medullary thyroid carcinoma cell line. Journal Of Biological Chemistry 1988, 263: 620-623. PMID: 3121619, DOI: 10.1016/s0021-9258(19)35397-9.Peer-Reviewed Original ResearchConceptsHypothalamic tissueCA77 cellsThyrotropin-releasing hormoneThyroid carcinoma cell linesRat medullary thyroid carcinoma cell lineMedullary thyroid carcinoma cell lineHormone messenger RNAPost-translational maturationCarcinoma cell linesImmunoreactive TRHRat hypothalamusPromising model systemGene regulationTRH precursorFurther studiesCell linesMessenger RNACell processesModel systemRNATissueRelative levels