2024
Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study
Estroff J, Devlin J, Hoteit L, Hassoune A, Neal M, Brown J, Lu L, Kotch S, Hazelton J, Christian A, Yeates E, Nahmias J, Jacobson L, Williams J, Schuster K, O'Connor R, Semon G, Straughn A, Cullinane D, Egodage T, Kincaid M, Rollins A, Amdur R, Sarani B. Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 97: 541-545. PMID: 38685190, DOI: 10.1097/ta.0000000000004345.Peer-Reviewed Original ResearchProthrombin complex concentrateAmount of RBC transfusionRed blood cell transfusionAndexanet alfaRed blood cellsRBC transfusionMulticenter study of adult patientsNon-inferiorityComparing prothrombin complex concentrateOral factor Xa inhibitorsStudy of adult patientsTransfused red blood cellsIncreased RBC transfusionsReversal of DOACsComplex concentrateFactor Xa inhibitorsTreatment of hemorrhageTraumatically injured patientsDOAC reversalMedian transfusionTransfusion rateUnit transfusionsMulticenter studyAdult patientsXa inhibitors
2023
Contemporary management and outcomes of penetrating colon injuries: Validation of the 2020 AAST Colon Organ Injury Scale
Zeineddin A, Tominaga G, Crandall M, Almeida M, Schuster K, Jawad G, Maqbool B, Sheffield A, Dhillon N, Radow B, Moorman M, Martin N, Jacovides C, Lowry D, Kaups K, Horwood C, Werner N, Proaño-Zamudio J, Kaafarani H, Marshall W, Haines L, Schaffer K, Staudenmayer K, Kozar R. Contemporary management and outcomes of penetrating colon injuries: Validation of the 2020 AAST Colon Organ Injury Scale. Journal Of Trauma And Acute Care Surgery 2023, 95: 213-219. PMID: 37072893, DOI: 10.1097/ta.0000000000003969.Peer-Reviewed Original ResearchConceptsOrgan Injury ScaleExtra-abdominal infectionsColon injuriesInjury ScaleAbbreviated Injury Scale scoreContemporary managementLevel 1 trauma centerAcute kidney injuryDamage control laparotomyInjury Scale scoreInjury Severity ScoreStrong predictive valueType of interventionAmerican AssociationKidney injuryLung injuryOperative findingsClinical outcomesPrimary repairSurgical managementTrauma centerMulticenter studyOperative managementPreoperative imagingRetrospective studyImaging acute cholecystitis, one test is enough
Schuster K, Schroeppel T, O'Connor R, Enniss T, Cripps M, Cullinane D, Kaafarani H, Crandall M, Puri R, Tominaga G. Imaging acute cholecystitis, one test is enough. The American Journal Of Surgery 2023, 226: 99-103. PMID: 36882336, DOI: 10.1016/j.amjsurg.2023.02.018.Peer-Reviewed Original ResearchConceptsCommon bile duct diameterBile duct diameterAcute cholecystitisIntra-class correlation coefficientDuct diameterRight upper quadrant painUpper quadrant painSigns of inflammationSingle imaging studyChi-square testQuadrant painPericholecystic fluidWall thicknessMulticenter studyPatientsImaging studiesCholecystitisAbnormal valuesGold standardAdequate informationPainInflammationAdmissionStudyDiagnosis
2018
Can acute care surgeons perform while fatigued? An EAST multicenter study
Schuster KM, Hazelton JP, Rattigan D, Nguyen L, Kim D, Spence LH, Turay D, Luo-Owen X, Perez JM, Dayal S, Blatt M, Hill C, Bhattacharya B. Can acute care surgeons perform while fatigued? An EAST multicenter study. Journal Of Trauma And Acute Care Surgery 2018, 85: 476-484. PMID: 29787535, DOI: 10.1097/ta.0000000000001975.Peer-Reviewed Original ResearchConceptsAcute care surgeonsMajor morbidityPatient outcomesAcute care surgery serviceEAST multicenter studyPatient-level factorsEmergency casesFour-level ordinal scaleHours of sleepHierarchical logistic regression modelsImpact of fatigueLogistic regression modelsPatient factorsFemale patientsSurgery serviceMulticenter studyLevel IVImmediate operationPrognostic studiesSleep timePatient volumeSimilar outcomesMorbiditySurgeonsMortality