1998
Network Analyses of Y-Chromosomal Types in Europe, Northern Africa, and Western Asia Reveal Specific Patterns of Geographic Distribution
Malaspina P, Cruciani F, Ciminelli B, Terrenato L, Santolamazza P, Alonso A, Banyko J, Brdicka R, García O, Gaudiano C, Guanti G, Kidd K, Lavinha J, Avila M, Mandich P, Moral P, Qamar R, Mehdi S, Ragusa A, Stefanescu G, Caraghin M, Tyler-Smith C, Scozzari R, Novelletto A. Network Analyses of Y-Chromosomal Types in Europe, Northern Africa, and Western Asia Reveal Specific Patterns of Geographic Distribution. American Journal Of Human Genetics 1998, 63: 847-860. PMID: 9718330, PMCID: PMC1377388, DOI: 10.1086/301999.Peer-Reviewed Original ResearchConceptsExtant human populationsTotal diversityChromosomal lineagesLength variantsDinucleotide microsatellitesY chromosomeCommon descentPhenetic relationshipsGeographic distributionNorthern AfricaHaplotypesHuman populationLineagesDinucleotide unitsRapid generationDiversityWestern AsiaNetwork analysisChromosomesMicrosatellitesSpecific patternsOptimal markerReliable frequency estimatesMutationsExtinction
1996
Chromosomal localization of long trinucleotide repeats in the human genome by fluorescence in situ hybridization
Haaf T, Sirugo G, Kidd K, Ward D. Chromosomal localization of long trinucleotide repeats in the human genome by fluorescence in situ hybridization. Nature Genetics 1996, 12: 183-185. PMID: 8563757, DOI: 10.1038/ng0296-183.Peer-Reviewed Original ResearchConceptsLong trinucleotide repeatsChromosomal localizationTrinucleotide repeatsHuman genomeNormal human genomeSitu hybridizationDifferent genetic diseasesUnstable trinucleotide repeatsChromosomal distributionTrinucleotide microsatellitesLarge repeatsAGG repeatsCCG repeatsRepeatsGenetic diseasesRepeat lociLarge CTG expansionsGenomeCTG expansionHybridizationPathological significanceMyotonic dystrophyMicrosatellitesLocalizationLoci