2021
Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region
Mestiri S, Boussetta S, Pakstis AJ, Elkamel S, Elgaaied ABA, Kidd KK, Cherni L. Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region. Gene 2021, 777: 145466. PMID: 33524518, DOI: 10.1016/j.gene.2021.145466.Peer-Reviewed Original ResearchMeSH KeywordsAdultAfrica, NorthernAllelesBlack PeopleEthnicityFemaleGene FrequencyGenetic Predisposition to DiseaseGenetic VariationGenomicsGenotypeGenotyping TechniquesHaplotypesHeterozygoteHuman MigrationHumansLinkage DisequilibriumMaleMiddle AgedPolymorphism, Single NucleotideProtein Serine-Threonine KinasesReceptors, Dopamine D2ConceptsNorth African populationsGenetic diversitySingle nucleotide polymorphismsGenetic structureAncestral gene poolPeculiar genetic structureLowest average heterozygosityNorth African onesAfrican populationsHigh linkage disequilibriumGenetic driftGenomic regionsAverage heterozygosityGene poolSame locusLinkage disequilibriumDisequilibrium analysisGenetic componentGenesNucleotide polymorphismsLociReceptor geneDiversityHuman populationEuropean populations
2013
An historical perspective on “The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus”
Kidd KK, Pakstis AJ, Yun L. An historical perspective on “The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus”. Human Genetics 2013, 133: 431-433. PMID: 24162668, DOI: 10.1007/s00439-013-1386-0.Peer-Reviewed Original ResearchConceptsThousands of lociGene frequency patternsPatterns of divergenceRandom genetic driftHuman population geneticsLow-frequency allelesDopamine D4 receptor locusGenetic driftPopulation geneticsImportant genesPopulation variationWorld-wide distributionReceptor locusFrequency allelesDifferent allelesLociDistinct populationsNative American populationsEast Asian populationsAllelesAllele frequenciesSame populationAmerican populationGenesGenetics
2007
Human genetic variation of medical significance
Kidd K, Kidd J. Human genetic variation of medical significance. 2007, 51-62. DOI: 10.1093/acprof:oso/9780199207466.003.0005.Peer-Reviewed Original ResearchGenetic variationNormal genetic variationRandom genetic driftSignificant genetic variationLoss of variationHuman genetic variationAllele frequency variationHuman evolutionary historyEvolutionary historyGenetic driftNatural selectionModern humansMedical significanceGeographic regionsLociHumansVariationSelectionDemographyMetabolismTaste perceptionComplex waysIsolationMigration
2003
Selective Pressure has not Acted Against Hypercoagulability Alleles in High‐Altitude Amerindians
Rupert J, Monsalve M, Kidd K, Tan C, Hochachka P, Devine D. Selective Pressure has not Acted Against Hypercoagulability Alleles in High‐Altitude Amerindians. Annals Of Human Genetics 2003, 67: 426-432. PMID: 12940916, DOI: 10.1046/j.1469-1809.2003.00043.x.Peer-Reviewed Original Research
1997
Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method
Sirugo G, Deinard A, Kidd J, Kidd K. Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method. Human Molecular Genetics 1997, 6: 403-408. PMID: 9147643, DOI: 10.1093/hmg/6.3.403.Peer-Reviewed Original ResearchConceptsCTG/CAGPygmy chimpanzeesCommon chimpanzeesRepeat lengthRandom genetic driftOrang-utansHuman populationDisease association studiesGenetic driftHuman genomeOverall mutation rateGenome scanAssociation studiesMutation rateBiaka PygmiesExpansion mutationRepeat expansionTotal genome scanPopulation differencesPopulation stratificationNon-human primatesRepeat expansion detection (RED) methodExpansion detectionChimpanzeesMutations
1996
Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method.
Grigorenko E, Shikanian A, Kidd D, Dorig R, Kidd K. Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method. Genetika 1996, 32: 1705-13. PMID: 9102365.Peer-Reviewed Original ResearchConceptsNatural selectionEffective population sizeRandom genetic driftMonte Carlo methodHaplotype frequenciesGenetic driftRandom matingEvolutionary dynamicsCarlo methodPopulation sizeRecurrent mutationsMutation processHarmonic meanFrequency dynamicsDifferent populationsSimulation resultsExperimental dataDynamicsMatingPopulationMutationsHaplotypesAllelesColonizationNew World colonization
1991
Drift, admixture, and selection in human evolution: a study with DNA polymorphisms.
Bowcock A, Kidd J, Mountain J, Hebert J, Carotenuto L, Kidd K, Cavalli-Sforza L. Drift, admixture, and selection in human evolution: a study with DNA polymorphisms. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 839-843. PMID: 1992475, PMCID: PMC50909, DOI: 10.1073/pnas.88.3.839.Peer-Reviewed Original ResearchConceptsDNA polymorphismsEqual evolutionary ratesRandom genetic driftEvolutionary ratesGenetic driftEvolutionary analysisNatural selectionGenetic markersHuman evolutionGene frequenciesEarly admixtureHuman differentiationEvolutionary modelsPolymorphismHigh variationLow variationGenetic polymorphismsMeasures of variationGenesPopulationSpeciesObserved distributionDifferentiationVariationSelection