1989
The mapping of the locus for multiple endocrine neoplasia type 2A by linkage with chromosome 10 markers.
Simpson N, Kidd K. The mapping of the locus for multiple endocrine neoplasia type 2A by linkage with chromosome 10 markers. Hormone And Metabolic Research. Supplement Series 1989, 21: 5-9. PMID: 2572529.Peer-Reviewed Original ResearchConceptsDisease locusInterstitial retinol-binding proteinChromosome 10 markersTest of linkageChromosome 10Disease genesDeletion siteChromosome 20Additional family dataBinding proteinLociGenesExclusion of linkageSitu hybridizationD10S5Ultimate identificationRetinol-binding proteinType 2AMultiple endocrine neoplasia type 2AGenomeMarkersFamily dataLinkageProteinHybridization
1988
Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease
Farrer L, Bonne-Tamir B, Frydman M, Magazanik A, Kidd K, Bowcock A, Cavalli-Sforza L. Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease. Human Genetics 1988, 79: 109-117. PMID: 3164701, DOI: 10.1007/bf00280547.Peer-Reviewed Original ResearchConceptsWilson disease locusDisease locusUnaffected individualsChromosome 13 markersWND locusMultipoint linkage analysisDisease familiesWilson disease familiesGenetic markersLinkage analysisChromosome 13Long armLociSources of variationAutosomal recessive disorderMore variationGenotypesCopper concentrationRecessive disorderNormal homozygotesWilson's diseaseFamilial componentMarkersCopper levelsSubsequent analysis
1987
Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage
Simpson N, Kidd K, Goodfellow P, McDermid H, Myers S, Kidd J, Jackson C, Duncan A, Farrer L, Brasch K, Castiglione C, Genel M, Gertner J, Greenberg C, Gusella J, Holden J, White B. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature 1987, 328: 528-530. PMID: 2886918, DOI: 10.1038/328528a0.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismIRBP geneNew DNA markersDifferent restriction fragment length polymorphismsPairwise linkage analysisChromosome 10 markersDNA markersFragment length polymorphismMaximum lod scoreLinkage analysisDisease locusLociMEN2A locusLOD scoreLength polymorphismGenesMultipoint analysisSecondary sitesType 2ADominant fashionKinds of cancers