2022
Genetic sensitivity to stress modifies the relationship between socioeconomic status and major adverse cardiovascular events
Abohashem S, Osborne M, Choi K, Liu Z, Zureigat H, Mezue K, Gharios C, Armstrong K, Smoller J, Tawakol A. Genetic sensitivity to stress modifies the relationship between socioeconomic status and major adverse cardiovascular events. European Heart Journal 2022, 43: ehac544.2265. DOI: 10.1093/eurheartj/ehac544.2265.Peer-Reviewed Original ResearchLow socioeconomic statusArea Deprivation IndexSocioeconomic statusMajor adverse cardiovascular eventsRisk associated with low socioeconomic statusCardiovascular diseaseMass General Brigham BiobankPolygenic risk scoresYears of follow-upAssociation with incident major adverse cardiovascular eventsIncident major adverse cardiovascular eventsDeprivation indexHome addressAssociated with major adverse cardiovascular eventsMedian incomeRisk scoreRisk factorsMediation analysisAdverse cardiovascular eventsNeural pathwaysFunding sourcesFollow-upCardiovascular eventsStress sensitivityIndividuals
2021
Social determinants and cardiovascular care: A focus on vulnerable populations and the Jamaica experience
Madu E, Mezue K, Madu K. Social determinants and cardiovascular care: A focus on vulnerable populations and the Jamaica experience. FASEB BioAdvances 2021, 3: 266-274. PMID: 33842851, PMCID: PMC8019262, DOI: 10.1096/fba.2020-00116.Peer-Reviewed Original ResearchSocial determinants of healthVulnerable populationsSocial determinantsConcept of social determinants of healthCardiovascular diseaseMedical careDeterminants of healthHigh-quality careCardiovascular disease careAt-risk populationsSDoH dataHealth inequalitiesHealthcare needsHealth outcomesCardiovascular careInfluence healthSocioeconomic statusEmployment statusCardiovascular servicesCareHealthAccess gapWork environmentBehavioral barriersPhysical environment