2017
Cognition and the course of prodromal Parkinson's disease
Weintraub D, Chahine LM, Hawkins KA, Siderowf A, Eberly S, Oakes D, Seibyl J, Stern MB, Marek K, Jennings D, Investigators T. Cognition and the course of prodromal Parkinson's disease. Movement Disorders 2017, 32: 1640-1645. PMID: 29063713, PMCID: PMC5722226, DOI: 10.1002/mds.27189.Peer-Reviewed Original ResearchConceptsSpeed/attentionCognitive declineProdromal participantsBaseline neuropsychological test performanceExecutive function/Role of cognitionNeuropsychological test performanceFuture cognitive declineBaseline cognitive scoresCognitive domainsGlobal cognitionBaseline cognitionCognitive scoresCognitionTest performanceFuture declinePD-convertersDopamine systemHyposmic individualsProdromal PDLongitudinal changesFunction/ParticipantsDopamine transporter bindingIndividuals
2015
Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings
Chahine M, Weintraub D, Hawkins KA, Siderowf A, Eberly S, Oakes D, Seibyl J, Stern MB, Marek K, Jennings D, Investigators T. Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings. Movement Disorders 2015, 31: 86-94. PMID: 26293177, PMCID: PMC4827252, DOI: 10.1002/mds.26373.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnxietyAttentionCocaineCognition DisordersCohort StudiesExecutive FunctionFemaleHumansLanguageMaleMemoryMiddle AgedNeurogenic BowelNeuropsychological TestsOlfaction DisordersParkinson DiseaseProtein BindingRadiopharmaceuticalsSelf ReportSeverity of Illness IndexStatistics, NonparametricSurveys and QuestionnairesTomography, Emission-Computed, Single-PhotonVisual PerceptionConceptsExecutive function/Global cognitionRelative impairmentSpecific cognitive domainsSpeed/attentionGlobal cognitive abilityNeuropsychological test batteryLower global cognitionFunction/Cognitive abilitiesCognitive domainsCognitive profileVisuospatial abilitiesLanguage domainsCognitive testingTest batteryCognitionNormative scoresMemoryLower mean scoresHealthy adultsNon-motor featuresIndividualsStudy findingsNon-motor symptoms
2012
The course of cognitive functioning over six months in individuals at clinical high risk for psychosis
Barbato M, Colijn MA, Keefe RS, Perkins DO, Woods SW, Hawkins KA, Christensen BK, Addington J. The course of cognitive functioning over six months in individuals at clinical high risk for psychosis. Psychiatry Research 2012, 206: 195-199. PMID: 23159196, PMCID: PMC3600156, DOI: 10.1016/j.psychres.2012.10.013.Peer-Reviewed Original ResearchConceptsClinical high riskCHR individualsComprehensive cognitive test batteryCognitive test batteryCognitive impairmentFuture longitudinal researchCognitive functioningCognitive performanceCognitive testsTest batteryLongitudinal researchCognitionPoor performanceLongitudinal changesPsychosisIndividualsParticipantsImpairmentBaseline participantsFunctioningPerformanceBatteriesResearchProdrome
2008
Everyday Decision-Making Ability in Older Persons With Cognitive Impairment
Lai JM, Gill TM, Cooney LM, Bradley EH, Hawkins KA, Karlawish JH. Everyday Decision-Making Ability in Older Persons With Cognitive Impairment. American Journal Of Geriatric Psychiatry 2008, 16: 693-696. PMID: 18669948, PMCID: PMC2730037, DOI: 10.1097/jgp.0b013e31816c7b54.Peer-Reviewed Original ResearchConceptsDecision-making abilityDecision-making capacityCognitive impairmentMacArthur Competency Assessment ToolExecutive functionMeasure of understandingOverall cognitionAssessment of capacityValid measureAlpha coefficientMedical treatment decisionsCronbach's alpha coefficientGood reliabilityImpairmentMeasuresACEDModerate correlationOlder personsCognitionAssessment toolPersonsAbilityReasoningCaregiversEveryday