Epigenetic regulation of smooth muscle cell plasticity
Liu R, Leslie KL, Martin KA. Epigenetic regulation of smooth muscle cell plasticity. Biochimica Et Biophysica Acta 2014, 1849: 448-453. PMID: 24937434, PMCID: PMC4552189, DOI: 10.1016/j.bbagrm.2014.06.004.Peer-Reviewed Original ResearchConceptsSMC plasticityEpigenetic regulationSmooth muscle cellsCell plasticitySmooth Muscle Cell PlasticityRegulatory cis elementsCell typesDNA demethylation pathwayLevel of epigeneticsMuscle cell plasticityMature cell typesKey transcription factorMajor cell typesHistone modificationsNovel target moleculesDNA methylationTranscription factorsEnvironmental stressCis elementsPhenotypic statesDemethylation pathwaySMC phenotypeMolecular mechanismsAdult bodyRemarkable plasticity