2010
Adiponectin Is Secreted by Vascular Smooth Muscle Cells and Regulates Muscle Contractile Phenotype
Ding M, Wagner R, Martin K. Adiponectin Is Secreted by Vascular Smooth Muscle Cells and Regulates Muscle Contractile Phenotype. The FASEB Journal 2010, 24: 957.5-957.5. DOI: 10.1096/fasebj.24.1_supplement.957.5.Peer-Reviewed Original ResearchAdiponectin overexpressionContractile phenotypeVSMC contractile proteinsVascular smooth muscle cellsSmooth muscle cellsContractile protein expressionVascular smooth muscle cell differentiationVSMC contractile phenotypeCardioprotective adipokineSmooth muscle cell differentiationVisceral fatReceptors AdipoR1Endogenous adiponectinRecombinant adiponectinAdiponectinParacrine actionCardioprotective functionParacrine mannerVSMC proliferationHigher order oligomeric formsSiRNA knock-downMuscle cell differentiationMuscle cellsContractile proteinsVSMC
2009
Adiponectin Induces Vascular Smooth Muscle Cell Differentiation via AMPK
Ding M, Wagner R, Fetalvero K, Kasza Z, Powell R, Martin K. Adiponectin Induces Vascular Smooth Muscle Cell Differentiation via AMPK. The FASEB Journal 2009, 23: 577.10-577.10. DOI: 10.1096/fasebj.23.1_supplement.577.10.Peer-Reviewed Original ResearchMTOR inhibitionLower adiponectin levelsVSMC differentiationType 2 diabetesVascular smooth muscle cell phenotypeSmooth muscle cell phenotypeAMPK activationDose-dependent mannerContractile protein expressionAMPK inhibitor compound C.Muscle cell phenotypeVascular smooth muscle cell differentiationVSMC contractile phenotypeAdipo-R1Smooth muscle cell differentiationAdiponectin levelsSerum hormonesCardioprotective roleHormonal inhibitorCardiovascular diseaseAdiponectinCardioprotective functionControl virusEndothelial cellsVSMC