Parathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy
Sun B, Mitnick M, Eielson C, Yao G, Paliwal I, Insogna K. Parathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy. Endocrinology 1997, 138: 3918-3924. PMID: 9275082, DOI: 10.1210/endo.138.9.5421.Peer-Reviewed Original ResearchConceptsLevels of fibronectinEffect of PTHAbility of PTHHuman PTHAdult female Sprague-Dawley ratsFemale Sprague-Dawley ratsCultured fetal rat bonesDiminished bone formationEstrogen-deficient stateHuman PTH-(1-34) infusionSprague-Dawley ratsFN productionFetal rat boneBisphosphonate APDHPTH groupPTH infusionCirculating LevelsAlzet minipumpsEstrogen deficiencyParathyroid hormoneEstrogen withdrawalBone resorptionAnabolic propertiesROS 17/2.8 cellsEffective agonistParathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy*
Sun B, Mitnick M, Eielson C, Yao G, Paliwal I, Insogna K. Parathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy*. Endocrinology 1997, 138: 3918-3924. DOI: 10.1210/en.138.9.3918.Peer-Reviewed Original ResearchResponse to PTHEffect of PTHHuman PTHCirculating levelsLevels of FNFN in vivoCultured fetal rat bonesAdult female Sprague-Dawley ratsFemale Sprague-Dawley ratsTreated with PTHVehicle infused groupFN productionEstrogen-deficient stateFetal rat bonesSignificant 2.4-fold increaseBlock bone resorptionSprague-Dawley ratsROS 17/2.8 cellsIn vitro studiesBisphosphonate APDEstrogen deficiencyAlzet minipumpsEstrogen withdrawalLevels in vivoBlunted response