2018
Vertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps
Hsieh E, Wang Q, Zhang R, Niu X, Xia W, Fraenkel L, Insogna KL, Li J, Smith JS, Zhou C, Qiao YL, Zhang P. Vertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps. BMC Cancer 2018, 18: 104. PMID: 29378534, PMCID: PMC5789645, DOI: 10.1186/s12885-018-4014-5.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsVertebral fracturesCancer survivorsCross-sectional studyBreast cancerBone lossCancer treatment-induced bone lossHealthy community-dwelling postmenopausal womenProgesterone receptor-positive breast cancerHealth servicesBreast cancer survivor cohortCommunity-dwelling postmenopausal womenFracture-related risk factorsPeking Vertebral Fracture StudyTreatment-induced bone lossReceptor-positive breast cancerChinese breast cancer survivorsCancer survivor cohortLarge cancer hospitalThoracolumbar X-rayVitamin D supplementsPrevalent vertebral fracturesBone density scanInitiation of treatmentAdjusted odds ratio
2017
The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes
Knobf MT, Jeon S, Smith B, Harris L, Thompson S, Stacy MR, Insogna K, Sinusas AJ. The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes. Heart & Lung 2017, 46: 375-381. PMID: 28803675, PMCID: PMC6129386, DOI: 10.1016/j.hrtlng.2017.06.001.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsCancer survivorsCenter interventionMET-minutes/weekStable insulin levelsMetabolic risk factorsResistance exercise programExercise stress testCardiovascular disease riskPhysical activity groupImproved insulin resistanceHeart rate recoveryMinutes/weekRisk reduction interventionsMajority of subjectsAdjuvant chemotherapyPremature menopauseExercise programInsulin levelsInsulin resistanceIntervention trialsRisk factorsCardiovascular functionBreast cancerRate recovery
2015
Osteoporosis-Related knowledge, self-efficacy and health beliefs among Chinese women with breast cancer
Hsieh E, Wang Q, Niu X, Fraenkel L, Bradley E, Insogna K, Xia W, Smith J, Qiao Y, Zhang P. Osteoporosis-Related knowledge, self-efficacy and health beliefs among Chinese women with breast cancer. Annals Of Global Health 2015, 81: 204. DOI: 10.1016/j.aogh.2015.02.970.Peer-Reviewed Original Research
2002
Overexpression of Parathyroid Hormone‐Related Protein Causes Hypercalcemia but Not Bone Metastases in a Murine Model of Mammary Tumorigenesis*
Wysolmerski JJ, Dann PR, Zelazny E, Dunbar ME, Insogna KL, Guise TA, Perkins AS. Overexpression of Parathyroid Hormone‐Related Protein Causes Hypercalcemia but Not Bone Metastases in a Murine Model of Mammary Tumorigenesis*. Journal Of Bone And Mineral Research 2002, 17: 1164-1170. PMID: 12096830, DOI: 10.1359/jbmr.2002.17.7.1164.Peer-Reviewed Original ResearchConceptsBone metastasesBreast cancer cellsCancer cellsTransgenic miceTumor-bearing transgenic miceParathyroid hormone-related proteinPrimary breast cancerProduction of PTHrPHormone-related proteinWild-type littermatesEffects of PTHrPCause hypercalcemiaWild-type controlsVisceral metastasesSkeletal metastasesParathyroid hormoneBone resorptionArterial circulationBreast cancerDMBA treatmentMammary carcinogenImmunodeficient miceMammary tumorigenesisMurine modelHigh incidence
1997
Estrogen Replacement Therapy: New Options, Continuing Concerns-Reply
Insogna K, Concato J, Henrich J. Estrogen Replacement Therapy: New Options, Continuing Concerns-Reply. JAMA 1997, 277: 1516-1517. DOI: 10.1001/jama.1997.03540430028020.Peer-Reviewed Original ResearchBreast cancer riskBreast cancerBone densityCancer riskLow endogenous estrogen levelsHigh endogenous estrogenEstrogen replacement therapyEndogenous estrogen levelsTreatment of osteoporosisHigher bone densityAfrican American womenEstrogen levelsReplacement therapyExogenous estrogenEstrogen influenceEndogenous estrogensLower riskCancerWomenOsteoporosisRiskEstrogenNew optionsTherapyBMD