2015
Bone Health and Osteoporosis
Lupsa BC, Insogna K. Bone Health and Osteoporosis. Endocrinology And Metabolism Clinics Of North America 2015, 44: 517-530. PMID: 26316240, DOI: 10.1016/j.ecl.2015.05.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBone healthBone lossLow bone massAdditional risk factorsDual-energy X-ray absorptiometry measurementsLow-energy fracturesBone mineral densityMicroarchitectural deteriorationEstrogen levelsSmoking cessationRisk factorsMineral densityPharmacologic agentsBone massHigh riskOlder womenWomen's ageBone strengthAbsorptiometry measurementsOsteoporosisGold standardBone tissueRiskHealthFractures
2008
Impact of Glucose‐Dependent Insulinotropic Peptide on Age‐Induced Bone Loss*
Ding K, Shi X, Zhong Q, Kang B, Xie D, Bollag WB, Bollag RJ, Hill W, Washington W, Mi Q, Insogna K, Chutkan N, Hamrick M, Isales CM. Impact of Glucose‐Dependent Insulinotropic Peptide on Age‐Induced Bone Loss*. Journal Of Bone And Mineral Research 2008, 23: 536-543. PMID: 18072880, PMCID: PMC2669161, DOI: 10.1359/jbmr.071202.Peer-Reviewed Original ResearchConceptsGlucose-dependent insulinotropic peptideAge-induced bone lossBone marrow stromal cellsGIP receptor expressionBone lossBone massMo of ageGIP effectsInsulinotropic peptideReceptor expressionEffects of GIPBone strengthOsteoblastic activityAge-associated bone lossElevated GIP levelsFunctional GIP receptorsWildtype control miceBone histomorphometric dataC57BL/6 transgenic miceAge-dependent fashionAge-related decreaseAge-related lossDifferentiation of BMSCsAge-dependent mannerAge-related changes