2024
Serum Lipoproteins Are Associated With Coronary Atherosclerosis in Asymptomatic U.S. Adults Without Traditional Risk Factors
Faridi K, Lahan S, Budoff M, Cury R, Feldman T, Pan A, Fialkow J, Nasir K. Serum Lipoproteins Are Associated With Coronary Atherosclerosis in Asymptomatic U.S. Adults Without Traditional Risk Factors. JACC Advances 2024, 3: 101049. DOI: 10.1016/j.jacadv.2024.101049.Peer-Reviewed Original ResearchTraditional risk factorsNon-HDL-CLDL-CRisk factorsAssociated with atherosclerosisCoronary atherosclerosisLipoprotein cholesterolAtherosclerotic cardiovascular disease riskSerum non-HDL-COptimal risk factorsLow-risk adultsActive tobacco useCardiovascular disease riskAssociation of low-density lipoprotein cholesterolAsymptomatic middle-aged adultsNon-high-density lipoprotein cholesterolAtherosclerosis prevalenceCoronary computed tomography angiographyHigh-risk plaque featuresMiddle-aged adultsAtherogenic lipoproteinsHigh LDL-CLow-density lipoprotein cholesterolLevels of atherogenic lipoproteinsMultivariate logistic regression
2023
Case report: Coronary atherosclerosis in a patient with long-standing very low LDL-C without lipid-lowering therapy
Mottola G, Welty F, Mojibian H, Faridi K. Case report: Coronary atherosclerosis in a patient with long-standing very low LDL-C without lipid-lowering therapy. Frontiers In Cardiovascular Medicine 2023, 10: 1272944. PMID: 37795488, PMCID: PMC10546007, DOI: 10.3389/fcvm.2023.1272944.Peer-Reviewed Case Reports and Technical NotesLipid-lowering therapyLDL-C levelsCoronary atherosclerosisLow LDL-C levelsLow-density lipoprotein cholesterolCardiovascular risk factorsLeft coronary systemRight coronary arteryLow serum levelsDevelopment of atherosclerosisNonobstructive coronary atherosclerosisRoutine laboratory dataTomography angiography scansApoB-containing lipoproteinsHeterozygous familial hypobetalipoproteinemiaAnomalous originMyxoma resectionAcute strokeAtrial myxomaCardiovascular riskLipoprotein cholesterolPlaque regressionDiabetes mellitusPrimordial preventionSerum levels
2019
Comparing different assessments of remnant lipoprotein cholesterol: The very large database of lipids
Faridi KF, Quispe R, Martin SS, Hendrani AD, Joshi PH, Brinton EA, Cruz DE, Banach M, Toth PP, Kulkarni K, Jones SR. Comparing different assessments of remnant lipoprotein cholesterol: The very large database of lipids. Journal Of Clinical Lipidology 2019, 13: 634-644. PMID: 31320236, DOI: 10.1016/j.jacl.2019.06.001.Peer-Reviewed Original ResearchConceptsLow-density lipoprotein cholesterolRemnant lipoprotein cholesterolLipoprotein cholesterolLipid parametersVertical auto profile ultracentrifugationRLP-C levelsAtherosclerotic cardiovascular diseaseLipid panelMedian ageHighest quintileRisk factorsCardiovascular diseaseSecond quintileFriedewald equationCholesterolQuintileDlRLPParameters correlatesSubject differencesLipidsCohortDisease
2015
Remnant Lipoprotein Cholesterol and Mortality After Acute Myocardial Infarction: Further Evidence for a Hypercholesterolemia Paradox From the TRIUMPH Registry
Martin SS, Faridi KF, Joshi PH, Blaha MJ, Kulkarni KR, Khokhar AA, Maddox TM, Havranek EP, Toth PP, Tang F, Spertus JA, Jones SR. Remnant Lipoprotein Cholesterol and Mortality After Acute Myocardial Infarction: Further Evidence for a Hypercholesterolemia Paradox From the TRIUMPH Registry. Clinical Cardiology 2015, 38: 660-667. PMID: 26459191, PMCID: PMC4715617, DOI: 10.1002/clc.22470.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersChi-Square DistributionCholesterolFemaleHumansHypercholesterolemiaKaplan-Meier EstimateLinear ModelsLipoproteinsMaleMiddle AgedMyocardial InfarctionProportional Hazards ModelsProspective StudiesProtective FactorsRegistriesRisk AssessmentRisk FactorsTime FactorsTriglyceridesUnited StatesUp-RegulationConceptsAcute myocardial infarctionHigh RLP-C levelsRLP-C levelsRemnant lipoprotein cholesterolLipoprotein cholesterolHazard ratioMyocardial infarctionAcute Coronary Events (GRACE) scoreIntermediate-density lipoprotein cholesterolLow-density lipoprotein cholesterolLipoprotein cholesterol subfractionsMortality 2 yearsUnknown protective factorsLead-time biasRegression hazard ratiosTriglyceride-rich lipoproteinsPrior observational studiesTRIUMPH registryCholesterol subfractionsLowest tertileAMI outcomesAMI survivorsHypercholesterolemic patientsMiddle tertileGlobal RegistryDeficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study
Lupton JR, Faridi KF, Martin SS, Sharma S, Kulkarni K, Jones SR, Michos ED. Deficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study. Journal Of Clinical Lipidology 2015, 10: 72-81.e1. PMID: 26892123, PMCID: PMC4762185, DOI: 10.1016/j.jacl.2015.09.006.Peer-Reviewed Original ResearchConceptsLow-density lipoprotein cholesterolIntermediate-density lipoprotein cholesterolAtherogenic lipid profileLipoprotein cholesterolRemnant lipoprotein cholesterolLipid profileLipid panelHigh-density lipoprotein cholesterolMultivariable-adjusted linear regressionVitamin D supplementationHigher total cholesterolSerum vitamin DCardiovascular disease riskLow serum HDLBlood urea nitrogenCross-sectional studyMultivariable linear regressionAdditional outcome measurementD supplementationGlycemic statusLow HDLHemoglobin A1cTotal cholesterolKidney functionSerum HDL