The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine
Zhou K, Sumigray KD, Lechler T. The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine. Molecular Biology Of The Cell 2015, 26: 1995-2004. PMID: 25833710, PMCID: PMC4472011, DOI: 10.1091/mbc.e14-10-1481.Peer-Reviewed Original ResearchMeSH KeywordsActin-Related Protein 2-3 ComplexActinsAnimalsEndosomesGene Knockout TechniquesImmunoglobulin GIntestinal AbsorptionIntestinal MucosaIntestine, SmallLipid MetabolismMiceTranscytosisConceptsArp2/3 complexVesicle traffickingCell type-specific phenotypesCortical F-actinF-actin assemblyEssential roleMammalian small intestineF-actin filamentsCell polarityEndolysosomal systemEssential functionsF-actinCortical poolCell migrationCultured cellsIntestinal developmentTraffickingIntestinal epitheliumPhenotypeWide arrayComplexesComplex functionsTranscytosisLipid absorptionTranscytosis of IgG