Cell-Cell Adhesions and Cell Contractility Are Upregulated upon Desmosome Disruption
Sumigray K, Zhou K, Lechler T. Cell-Cell Adhesions and Cell Contractility Are Upregulated upon Desmosome Disruption. PLOS ONE 2014, 9: e101824. PMID: 25006807, PMCID: PMC4090201, DOI: 10.1371/journal.pone.0101824.Peer-Reviewed Original ResearchConceptsAdherens junctionsMyosin IIAAdhesion structuresAnti-Dsg3 antibodiesCell-cell adhesion structuresCell adhesion structuresCell-cell adhesionMyosin II activityDesmosomal protein desmoplakinDesmosome functionTransmembrane componentBarrier functionClaudin genesGenetic disordersSignificant increaseMouse keratinocytesCell contractilityDisruption resultsPosttranslational changesTight junctionsII activity