2023
Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol
Kitay B, Murphy E, Macaluso M, Corlett P, Hershenberg R, Joormann J, Martinez-Kaigi V, Nikayin S, Rhee T, Sanacora G, Shelton R, Thase M, Wilkinson S. Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol. Psychiatry Research 2023, 330: 115585. PMID: 37935086, DOI: 10.1016/j.psychres.2023.115585.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMajor depressionSuicidal ideationRelapse preventionBehavioral therapyStudy protocolHigh riskClinical trial study protocolLong-term treatment approachKey secondary outcomesTrial study protocolHigh relapse rateHigh-risk populationSignificant suicidal ideationHospital dischargeSecondary outcomesPrimary outcomeRelapse rateFeasibility trialEsketamineTreatment approachesPatientsSuicide attemptsTherapySupplemental indications
2022
Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision
Jones C, An X, Ji Y, Liu M, Zeng D, House S, Beaudoin F, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Punches B, Lyons M, Kurz M, Swor R, McGrath M, Hudak L, Pascual J, Seamon M, Datner E, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, Koenen K, Ressler K, Kessler R, McLean S. Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision. Annals Of Emergency Medicine 2022, 81: 249-261. PMID: 36328855, PMCID: PMC11181458, DOI: 10.1016/j.annemergmed.2022.08.011.Peer-Reviewed Original ResearchConceptsMotor vehicle collisionsPosttraumatic stress symptomsValidation cohortSubstantial posttraumatic stress symptomsStress symptomsVehicle collisionsRisk-stratify individualsClinical decision support toolEmergency department patientsPersistent posttraumatic stress symptomsPreventive intervention trialNumber of EDsEase of administrationDerivation cohortPrimary outcomeDepartment patientsIntervention trialsBaseline healthHigh riskSymptomsCohortExternal validationPsychological recoveryDiscriminative abilityPosttraumatic stress
2021
Depression Predicts Global Functional Outcomes in Individuals at Clinical High Risk for Psychosis
Deng W, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Perkins DO, Seidman LJ, Tsuang MT, Woods SW, Walker EF, Joormann J, Cannon T. Depression Predicts Global Functional Outcomes in Individuals at Clinical High Risk for Psychosis. Psychiatric Research And Clinical Practice 2021, 3: 163-171. PMID: 36101655, PMCID: PMC9175802, DOI: 10.1176/appi.prcp.20210023.Peer-Reviewed Original ResearchGlobal functional outcomeFunctional outcomeCHR-P populationDepressive symptomsCHR individualsBetter global functional outcomeCo-occurring depressive symptomsCo-morbid depressionPoor functional outcomeBaseline depressive symptomsDepressive symptom scoresLongitudinal study cohortClinical high riskProdromal symptom severityFunctional recoveryStudy cohortSymptom scoresPoor outcomeFavorable courseFunctional improvementHigh riskAffective symptomsDegree of recoverySymptomsGlobal functioningDevelopment and Validation of a Model to Predict Posttraumatic Stress Disorder and Major Depression After a Motor Vehicle Collision
Ziobrowski HN, Kennedy CJ, Ustun B, House SL, Beaudoin FL, An X, Zeng D, Bollen KA, Petukhova M, Sampson NA, Puac-Polanco V, Lee S, Koenen KC, Ressler KJ, McLean SA, Kessler RC, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Lyons M, Murty V, McGrath M, Pascual J, Seamon M, Datner E, Chang A, Pearson C, Peak D, Jambaulikar G, Merchant R, Domeier R, Rathlev N, O’Neil B, Sergot P, Sanchez L, Bruce S, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Harte S, Elliott J, van Rooij S. Development and Validation of a Model to Predict Posttraumatic Stress Disorder and Major Depression After a Motor Vehicle Collision. JAMA Psychiatry 2021, 78: 1228-1237. PMID: 34468741, PMCID: PMC8411364, DOI: 10.1001/jamapsychiatry.2021.2427.Peer-Reviewed Original ResearchMeSH KeywordsAccidents, TrafficAdolescentAdultAgedDepressive Disorder, MajorEmergency Service, HospitalFemaleHumansLongitudinal StudiesMachine LearningMaleMiddle AgedModels, TheoreticalPrognosisPsychological TraumaPsychometricsRisk AssessmentStress Disorders, Post-TraumaticWounds and InjuriesYoung AdultConceptsMajor depressive episodePosttraumatic stress disorderEmergency departmentUrban emergency departmentMotor vehicle collisionsSurvey 2 weeksDepressive episodeED assessmentMAIN OUTCOMEHigh riskPatientsPreventive interventionsED reportsPTSD ChecklistStress disorderSubstantial proportionLongitudinal studyVehicle collisionsDSM-5Prognostic reportsTraumatic eventsWeeksMonthsTraumatic experiencesReport