Depression Predicts Global Functional Outcomes in Individuals at Clinical High Risk for Psychosis
Deng W, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Perkins DO, Seidman LJ, Tsuang MT, Woods SW, Walker EF, Joormann J, Cannon T. Depression Predicts Global Functional Outcomes in Individuals at Clinical High Risk for Psychosis. Psychiatric Research And Clinical Practice 2021, 3: 163-171. PMID: 36101655, PMCID: PMC9175802, DOI: 10.1176/appi.prcp.20210023.Peer-Reviewed Original ResearchGlobal functional outcomeFunctional outcomeCHR-P populationDepressive symptomsCHR individualsBetter global functional outcomeCo-occurring depressive symptomsCo-morbid depressionPoor functional outcomeBaseline depressive symptomsDepressive symptom scoresLongitudinal study cohortClinical high riskProdromal symptom severityFunctional recoveryStudy cohortSymptom scoresPoor outcomeFavorable courseFunctional improvementHigh riskAffective symptomsDegree of recoverySymptomsGlobal functioning