Neuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda
Fins* J, Illes* J, Bernat** J, Hirsch** J, Laureys** S, Murphy** E. Neuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda. The American Journal Of Bioethics 2008, 8: 3-12. PMID: 18853371, DOI: 10.1080/15265160802318113.Peer-Reviewed Original ResearchMeSH KeywordsBrain InjuriesConsciousnessConsciousness DisordersCooperative BehaviorDiagnostic Techniques, NeurologicalEthics, ResearchHuman ExperimentationHumansNervous System Physiological PhenomenaNeurologyPainPatient SelectionPersistent Vegetative StatePhysical StimulationResearch DesignSocial JusticeThird-Party ConsentConceptsDisorders of consciousnessEthical research agendaEthical reflectionEthical framesScientific progressScientific backdropConsciousnessConscious stateLimited stateInterdisciplinary approachWorking meetingsResearch agendaEthicsNeuroethicsNeuroscientistsReflectionBackdropStanford UniversityAgendaUnderstandingConferenceTranslationLeptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli. Journal Of Clinical Investigation 2008, 118: 2583-2591. PMID: 18568078, PMCID: PMC2430499, DOI: 10.1172/jci35055.Peer-Reviewed Original ResearchMeSH KeywordsAdultAppetite RegulationBrainCerebral CortexEcho-Planar ImagingFemaleFoodHumansHypothalamusInjections, SubcutaneousLeptinLimbic SystemMaleNervous System Physiological PhenomenaOxygenPhotic StimulationWeight LossConceptsMiddle frontal gyrusNeural activityFood cuesFrontal gyrusFood-related visual cuesWeight lossFood intakeWeight loss-induced changesVisual food cuesVisual food stimuliMiddle temporal gyrusRelative leptin deficiencyWeight-reduced stateDaily subcutaneous injectionsBody weight maintenanceCognitive controlFood stimuliTemporal gyrusVisual cuesLeptin deficiencyObese subjectsWeight maintenanceLingual gyrusClinical managementFunctional MRI