2023
Neural mechanisms for emotional contagion and spontaneous mimicry of live facial expressions
Hirsch J, Zhang X, Noah J, Bhattacharya A. Neural mechanisms for emotional contagion and spontaneous mimicry of live facial expressions. Philosophical Transactions Of The Royal Society B Biological Sciences 2023, 378: 20210472. PMID: 36871593, PMCID: PMC9985973, DOI: 10.1098/rstb.2021.0472.Peer-Reviewed Original ResearchConceptsEmotional contagionFacial expressionsFacial mimicryNeural correlatesAffect ratingsDyadic partnersFace processing areasRatings of emotionDistinct neural componentsShort movie clipsTwo-person paradigmFacial action unitsSpontaneous mimicryNeural underpinningsEmotional experienceNeural mechanismsSupramarginal gyrusNatural facial expressionsAction unitsRest blocksMovie clipsSocial interactionFacial classificationMovie watchersDyadic role
2020
Facial and neural mechanisms during interactive disclosure of biographical information
Cañigueral R, Zhang X, Noah JA, Tachtsidis I, Hamilton AFC, Hirsch J. Facial and neural mechanisms during interactive disclosure of biographical information. NeuroImage 2020, 226: 117572. PMID: 33221448, PMCID: PMC7612862, DOI: 10.1016/j.neuroimage.2020.117572.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexDisclosureEye Movement MeasurementsFacial ExpressionFacial MusclesFemaleFixation, OcularFunctional NeuroimagingHumansMaleMiddle AgedParietal LobePrefrontal CortexSelf DisclosureSignal Processing, Computer-AssistedSocial InteractionSpectroscopy, Near-InfraredTemporal LobeYoung AdultConceptsNeurocognitive mechanismsFacial displaysCommunicative interactionMore eye gazeNon-interactive situationsPairs of participantsBiographical informationBilateral TPJRight TPJLeft SMGNeuroscience hypothesisNeural mechanismsEye gazeMultimodal findingsBrain activitySocial signalingTPJDLPFCMutual sharingParticipantsSpontaneous productionLong-range mechanismsGazeDisplaySynchrony
2018
Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment
Fertuck EA, Grinband J, Mann JJ, Hirsch J, Ochsner K, Pilkonis P, Erbe J, Stanley B. Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment. NeuroImage Clinical 2018, 21: 101616. PMID: 30639176, PMCID: PMC6411618, DOI: 10.1016/j.nicl.2018.101616.Peer-Reviewed Original Research
2013
Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment
Pantazatos SP, Talati A, Schneier FR, Hirsch J. Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment. Neuropsychopharmacology 2013, 39: 425-434. PMID: 24084831, PMCID: PMC3870777, DOI: 10.1038/npp.2013.211.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderFunctional connectivityAnxiety disordersFace perceptionTemporal poleFunctional magnetic resonance imaging studyPanic disorderSpecific anxiety disordersIndependent replication sampleHippocampal functional connectivityMagnetic resonance imaging studyFace processingPerceptual tasksResonance imaging studyBrain activationSAD diagnosisReplication sampleHIGH-SADSAD samplesSimilar tasksDisorder-specific biomarkersFC featuresSymptom severityAnterior temporalPerception
2012
Decoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Decoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity. PLOS Computational Biology 2012, 8: e1002441. PMID: 22479172, PMCID: PMC3315448, DOI: 10.1371/journal.pcbi.1002441.Peer-Reviewed Original ResearchConceptsFearful facesEmotional expressionBilateral middle temporal gyrusThreat-related stimuliUnattended fearful facesLarge-scale functional connectivityMultiple functional connectionsFunctional magnetic resonanceWhole-brain patternsMiddle temporal gyrusWhole-brain correlationActive research goalNeutral facesEmotion processingFear perceptionImplicit fearImplicit presentationAngular gyrusChance accuracyTemporal gyrusBrain activityFace presentationPrefrontal cortexParietal regionsFunctional connectivityCortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Cortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing. NeuroImage 2012, 61: 1355-1363. PMID: 22484206, PMCID: PMC3393600, DOI: 10.1016/j.neuroimage.2012.03.051.Peer-Reviewed Original ResearchConceptsFunctional connectivityAffective stimuliCortical-subcortical functional connectivityFearful face processingFear-related stimuliAmygdala functional connectivityMiddle temporal gyrusCortical structuresKey limbic regionsFace processingEmotion processingFear conditionFear processingSubconscious processingAngular gyrusTemporal gyrusCortical functional connectivityRight amygdalaLimbic regionsFC featuresStimuliGyrusProcessingTraining dataPrecuneus
2006
Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis
McClelland S, Garcia RE, Peraza DM, Shih TT, Hirsch LJ, Hirsch J, Goodman RR. Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis. Epilepsia 2006, 47: 1337-1342. PMID: 16922878, DOI: 10.1111/j.1528-1167.2006.00557.x.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisAnteromedial temporal lobectomyTemporal lobe epilepsyTLE onsetTemporal sclerosisTemporal lobectomyRight amygdalaEarly-onset patientsLate-onset patientsEarly-onset groupLate-onset groupAmygdalar damageAge 6 yearsFER impairmentPostsurgical populationLobe epilepsyLeft-hemisphere language dominancePreoperative MRIPatientsFrightened expressionImpaired facial emotion recognitionLobectomySclerosisAmygdalaOnset
2004
Individual Differences in Trait Anxiety Predict the Response of the Basolateral Amygdala to Unconsciously Processed Fearful Faces
Etkin A, Klemenhagen KC, Dudman JT, Rogan MT, Hen R, Kandel ER, Hirsch J. Individual Differences in Trait Anxiety Predict the Response of the Basolateral Amygdala to Unconsciously Processed Fearful Faces. Neuron 2004, 44: 1043-1055. PMID: 15603746, DOI: 10.1016/j.neuron.2004.12.006.Peer-Reviewed Original ResearchConceptsTrait anxietyFearful facesIndividual differencesDorsal amygdalaThreat-related stimuliBasolateral amygdalaSubjects' reaction timesReaction timeConscious stimuliUnconscious stimuliUnconscious processingConscious processingThreat sensitivityUnconscious perceptionUnconscious processesNeural responsesBasolateral subregionsNeural systemsAnxietyAmygdalaStimuliBiological basisProcessingFaceFMRI