2015
A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder
Talati A, Pantazatos SP, Hirsch J, Schneier F. A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder. Psychiatry Research 2015, 231: 279-285. PMID: 25659476, PMCID: PMC4363180, DOI: 10.1016/j.pscychresns.2015.01.008.Peer-Reviewed Original ResearchConceptsParoxetine treatmentSignificant gray matter reductionsGray matter volume changesAnxiety disordersNeuro-anatomical changesGray matter reductionsSocial anxiety disorderClinical responseLiebowitz Social Anxiety ScaleSymptom improvementRight thalamusVBM8 toolboxLeft thalamusSuccessful treatmentWeek 8Bilateral caudateControl groupGray matterDSM-IVSymptom severityLongitudinal changesPilot study
2011
Neural response to eye contact and paroxetine treatment in generalized social anxiety disorder
Schneier FR, Pomplun M, Sy M, Hirsch J. Neural response to eye contact and paroxetine treatment in generalized social anxiety disorder. Psychiatry Research 2011, 194: 271-278. PMID: 22047726, PMCID: PMC3230304, DOI: 10.1016/j.pscychresns.2011.08.006.Peer-Reviewed Original ResearchConceptsParoxetine treatmentInferior parietal lobuleGeneralized social anxiety disorderNeural responsesPosterior cingulateParietal lobuleAnxiety disordersGSAD patientsEye contactMiddle occipital cortexMiddle frontal gyrusFunctional magnetic resonanceSymptomatic improvementHealthy comparison participantsOccipital cortexSocial anxiety disorderSymptom reductionAnterior cingulatePatientsUnmedicated adultsParahippocampal cortexNeural circuitrySupramarginal gyrusFrontal gyrusCingulate