2020
Facial and neural mechanisms during interactive disclosure of biographical information
Cañigueral R, Zhang X, Noah JA, Tachtsidis I, Hamilton AFC, Hirsch J. Facial and neural mechanisms during interactive disclosure of biographical information. NeuroImage 2020, 226: 117572. PMID: 33221448, PMCID: PMC7612862, DOI: 10.1016/j.neuroimage.2020.117572.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexDisclosureEye Movement MeasurementsFacial ExpressionFacial MusclesFemaleFixation, OcularFunctional NeuroimagingHumansMaleMiddle AgedParietal LobePrefrontal CortexSelf DisclosureSignal Processing, Computer-AssistedSocial InteractionSpectroscopy, Near-InfraredTemporal LobeYoung AdultConceptsNeurocognitive mechanismsFacial displaysCommunicative interactionMore eye gazeNon-interactive situationsPairs of participantsBiographical informationBilateral TPJRight TPJLeft SMGNeuroscience hypothesisNeural mechanismsEye gazeMultimodal findingsBrain activitySocial signalingTPJDLPFCMutual sharingParticipantsSpontaneous productionLong-range mechanismsGazeDisplaySynchrony
2018
A cross-brain neural mechanism for human-to-human verbal communication
Hirsch J, Noah J, Zhang X, Dravida S, Ono Y. A cross-brain neural mechanism for human-to-human verbal communication. Social Cognitive And Affective Neuroscience 2018, 13: 907-920. PMID: 30137601, PMCID: PMC6137318, DOI: 10.1093/scan/nsy070.Peer-Reviewed Original ResearchConceptsSuperior temporal gyrusInteractive brain hypothesisNeural mechanismsSocial interactionBrain hypothesisCanonical language areasHuman verbal communicationNon-interactive conditionDynamic social interactionsObject NamingSocial cuesInterpersonal informationBrain substratesDescription taskTemporal gyrusBroca's areaLanguage areasWernicke's areaNeural activitySubcentral areaVerbal communicationNatural settingsTheoretical frameworkGeneral theoretical frameworkDeoxyhemoglobin signal
2017
Frontal temporal and parietal systems synchronize within and across brains during live eye-to-eye contact
Hirsch J, Zhang X, Noah JA, Ono Y. Frontal temporal and parietal systems synchronize within and across brains during live eye-to-eye contact. NeuroImage 2017, 157: 314-330. PMID: 28619652, PMCID: PMC5863547, DOI: 10.1016/j.neuroimage.2017.06.018.Peer-Reviewed Original ResearchConceptsEye contactInterpersonal interactionsSupplementary motor cortexSpecificity hypothesisFrontal clusterSubcentral areaLeft superior temporal gyrusInteractive brain hypothesisTwo-person neuroscienceLimited head motionSuperior temporal gyrusTwo-person interactionsConventional neuroimaging methodsNeural correlatesSocial cuesNeural processesBrain hypothesisNeural mechanismsNeural responsesParietal systemSupramarginal gyrusMutual gazeSynchrony hypothesisLanguage functionTemporal gyrusNeural correlates of conflict between gestures and words: A domain-specific role for a temporal-parietal complex
Noah JA, Dravida S, Zhang X, Yahil S, Hirsch J. Neural correlates of conflict between gestures and words: A domain-specific role for a temporal-parietal complex. PLOS ONE 2017, 12: e0173525. PMID: 28278240, PMCID: PMC5344449, DOI: 10.1371/journal.pone.0173525.Peer-Reviewed Original ResearchConceptsTemporal-parietal junctionDorsolateral prefrontal cortexRight temporal-parietal junctionRight dorsolateral prefrontal cortexLeft dorsolateral prefrontal cortexSuperior temporal gyrusColor taskConflict taskIncongruent trialsSocial cuesGesture tasksSupramarginal gyrusBehavioral interference effectDomain-general mechanismsUnderlying neural processesReceptive language areasHuman social behaviorAuditory association cortexDomain-specific rolesFrontal eye fieldConflict processing mechanismCongruent trialsGestural cuesNeural correlatesNeural processes
2013
Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment
Pantazatos SP, Talati A, Schneier FR, Hirsch J. Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment. Neuropsychopharmacology 2013, 39: 425-434. PMID: 24084831, PMCID: PMC3870777, DOI: 10.1038/npp.2013.211.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderFunctional connectivityAnxiety disordersFace perceptionTemporal poleFunctional magnetic resonance imaging studyPanic disorderSpecific anxiety disordersIndependent replication sampleHippocampal functional connectivityMagnetic resonance imaging studyFace processingPerceptual tasksResonance imaging studyBrain activationSAD diagnosisReplication sampleHIGH-SADSAD samplesSimilar tasksDisorder-specific biomarkersFC featuresSymptom severityAnterior temporalPerception
2012
Conceptual representations of perceptual knowledge
Smith EE, Myers N, Sethi U, Pantazatos S, Yanagihara T, Hirsch J. Conceptual representations of perceptual knowledge. Cognitive Neuropsychology 2012, 29: 237-248. PMID: 22994286, PMCID: PMC3516296, DOI: 10.1080/02643294.2012.706218.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusFunctional magnetic resonance imagingFusiform gyrusPerceptual propertiesPerceptual knowledgeLeft inferior frontal gyrusLeft fusiform gyrusMiddle temporal gyrusPerceptual processingAmodal processesModality-specific mannerSemantic memoryBehavioral performanceFrontal gyrusThompson-SchillConceptual representationKan et alVerbal statementsGyrusParticipantsProcessingMagnetic resonance imagingRepresentationBarsalouMemory
2007
Cortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging
Marian V, Shildkrot Y, Blumenfeld HK, Kaushanskaya M, Faroqi-Shah Y, Hirsch J. Cortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging. Journal Of Clinical And Experimental Neuropsychology 2007, 29: 247-265. PMID: 17454346, DOI: 10.1080/13803390600659376.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdultCerebral CortexData Interpretation, StatisticalFemaleFrontal LobeFunctional LateralityHumansImage Processing, Computer-AssistedLanguage TestsMagnetic Resonance ImagingMaleMental ProcessesMultilingualismNerve NetOccipital LobeSpeech PerceptionTemporal LobeConceptsInferior frontal gyrusLeft inferior frontal gyrusFunctional magnetic resonance imagingLexical processingSuperior temporal gyrusSecond languageCenter of activationCortical activationRight inferior frontal gyrusRussian-English bilingualsCortical organizationSimilar cortical networksLate bilingualsTranslation equivalentsOrthographic processingPhonological processingSame languageWord processingInferior frontalFrontal gyrusSupramarginal gyrusLanguageDifferent wordsTemporal gyrusBilinguals
2006
Predictive Codes for Forthcoming Perception in the Frontal Cortex
Summerfield C, Egner T, Greene M, Koechlin E, Mangels J, Hirsch J. Predictive Codes for Forthcoming Perception in the Frontal Cortex. Science 2006, 314: 1311-1314. PMID: 17124325, DOI: 10.1126/science.1132028.Peer-Reviewed Original ResearchConceptsFrontal cortexIncoming sensory informationMedial frontal cortexPresence of facesPerceptual ambiguityPerceptual decisionsSensory evidenceNeural representationVisual objectsSensory environmentVisual areasPredictive codingSensory informationPredictive codePerceptionCortexFaceHuman subjectsBrainObserved evidenceDecisionsAmbiguityRepresentationEvidenceObjectsFacial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis
McClelland S, Garcia RE, Peraza DM, Shih TT, Hirsch LJ, Hirsch J, Goodman RR. Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis. Epilepsia 2006, 47: 1337-1342. PMID: 16922878, DOI: 10.1111/j.1528-1167.2006.00557.x.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisAnteromedial temporal lobectomyTemporal lobe epilepsyTLE onsetTemporal sclerosisTemporal lobectomyRight amygdalaEarly-onset patientsLate-onset patientsEarly-onset groupLate-onset groupAmygdalar damageAge 6 yearsFER impairmentPostsurgical populationLobe epilepsyLeft-hemisphere language dominancePreoperative MRIPatientsFrightened expressionImpaired facial emotion recognitionLobectomySclerosisAmygdalaOnset
2005
fMRI reveals large-scale network activation in minimally conscious patients
Schiff N, Rodriguez-Moreno D, Kamal A, Kim K, Giacino J, Plum F, Hirsch J. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005, 64: 514-523. PMID: 15699384, DOI: 10.1212/01.wnl.0000150883.10285.44.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdultAttentionAuditory CortexAwarenessCerebral HemorrhageCraniocerebral TraumaEncephalomalaciaFixation, OcularHumansLanguageMagnetic Resonance ImagingMalePersistent Vegetative StatePhysical StimulationSomatosensory CortexTemporal LobeTouchVerbal BehaviorWounds, NonpenetratingConceptsCognitive functionCortical activityLanguage-related tasksResidual cognitive functionMiddle temporal gyrusTactile stimulationMeaningless stimuliActive cortical networkConscious stateLanguage stimulationNeurobiological correlatesLanguage functionTemporal gyrusBehavioral evidenceMCS patientsCortical systemsLinguistic contentAuditory stimulationCortical networksLanguage processingCerebral networksNetwork activationCortical responsesCommunication abilityFMRI mapsIntentional false responding shares neural substrates with response conflict and cognitive control
Nuñez JM, Casey BJ, Egner T, Hare T, Hirsch J. Intentional false responding shares neural substrates with response conflict and cognitive control. NeuroImage 2005, 25: 267-277. PMID: 15734361, DOI: 10.1016/j.neuroimage.2004.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAdultArousalAutobiographies as TopicBrainCaudate NucleusConflict, PsychologicalDeceptionDominance, CerebralFemaleGyrus CinguliHumansImage Processing, Computer-AssistedIntentionInternal-External ControlMagnetic Resonance ImagingMaleNerve NetNeural InhibitionParietal LobePersonality InventoryPrefrontal CortexReaction TimeTemporal LobeThalamic NucleiConceptsDorsolateral prefrontal cortexCognitive controlResponse conflictAnterior cingulate cortexPsychopathic Personality InventoryCingulate cortexSelf-report personality measuresSelf-relevant stimuliFalse responsesAmount of conflictPosterior cingulate cortexResponse inhibitionNeural substratesCaudate activityMesial prefrontalNeural effectsPersonality measuresCognitive functionPersonal relevancePrefrontal cortexAnterior cingulateNeural activityAutobiographical responsesProcess of interferenceResponse conditions
1999
Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping
Ruge M, Victor J, Hosain S, Correa D, Relkin N, Tabar V, Brennan C, Gutin P, Hirsch J. Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping. Stereotactic And Functional Neurosurgery 1999, 72: 95-102. PMID: 10853058, DOI: 10.1159/000029706.Peer-Reviewed Original ResearchConceptsDirect cortical stimulationIntraoperative electrophysiologyCortical stimulationSensorimotor cortexIntraoperative language mappingFunctional magnetic resonance imagingMagnetic resonance imagingSSEP recordingsLocalization of functionMotor cortexIntraoperative localizationPreoperative toolResonance imagingLanguage mappingCortexWernicke's areaElectrophysiologyFMRIPresent studyStimulationSensorimotor mappingConcordancePatientsBroca
1997
Distinct cortical areas associated with native and second languages
Kim K, Relkin N, Lee K, Hirsch J. Distinct cortical areas associated with native and second languages. Nature 1997, 388: 171-174. PMID: 9217156, DOI: 10.1038/40623.Peer-Reviewed Original ResearchConceptsSecond languageFunctional magnetic resonance imagingMultiple language functionsLanguage-specific regionsCortical areasEssential human capacitiesFrontal cortical areasLanguage acquisitionNative languageBilingual subjectsMultiple languagesDistinct cortical areasLanguageLanguage functionBroca's areaCortical representationHuman capacityHuman brainHuman cortexAcquisition stageSeparation of activitiesMagnetic resonance imagingResonance imagingFundamental questionsAdulthood