Reproducibility of single‐ and multi‐voxel 1H MRS measurements of intramyocellular lipid in overweight and lean subjects under conditions of controlled dietary calorie and fat intake
Shen W, Mao X, Wolper C, Heshka S, Dashnaw S, Hirsch J, Heymsfield SB, Shungu DC. Reproducibility of single‐ and multi‐voxel 1H MRS measurements of intramyocellular lipid in overweight and lean subjects under conditions of controlled dietary calorie and fat intake. NMR In Biomedicine 2008, 21: 498-506. PMID: 17955571, PMCID: PMC2892914, DOI: 10.1002/nbm.1218.Peer-Reviewed Original ResearchConceptsIntramyocellular lipidsLean subjectsSV-MRSTotal muscle creatineTibialis anterior muscleOverweight subjectsFat intakeDietary fatAnterior muscleCalorie intakeMuscle creatineFemale CaucasiansDietary caloriesDuplicate measuresMRS measurementsIntakeMRSISubjectsShorter scan timeTCRDaysOverweightLipidsCoefficient of variation