2008
Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli. Journal Of Clinical Investigation 2008, 118: 2583-2591. PMID: 18568078, PMCID: PMC2430499, DOI: 10.1172/jci35055.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusNeural activityFood cuesFrontal gyrusFood-related visual cuesWeight lossFood intakeWeight loss-induced changesVisual food cuesVisual food stimuliMiddle temporal gyrusRelative leptin deficiencyWeight-reduced stateDaily subcutaneous injectionsBody weight maintenanceCognitive controlFood stimuliTemporal gyrusVisual cuesLeptin deficiencyObese subjectsWeight maintenanceLingual gyrusClinical managementFunctional MRIA case of locked-in syndrome complicated by central deafness
Smart CM, Giacino JT, Cullen T, Rodriguez Moreno D, Hirsch J, Schiff ND, Gizzi M. A case of locked-in syndrome complicated by central deafness. Nature Reviews Neurology 2008, 4: 448-453. PMID: 18506168, DOI: 10.1038/ncpneuro0823.Peer-Reviewed Original Research
2006
Corrigendum to “Responsivity to food stimuli in obese and lean binge eaters using functional MRI” [Appetite 46 (2006) 31–35]
Geliebter A, Ladell T, Logan M, Schneider T, Sharafi M, Hirsch J. Corrigendum to “Responsivity to food stimuli in obese and lean binge eaters using functional MRI” [Appetite 46 (2006) 31–35]. Appetite 2006, 46: 395. DOI: 10.1016/j.appet.2006.01.013.Peer-Reviewed Original ResearchA Neural Representation of Categorization Uncertainty in the Human Brain
Grinband J, Hirsch J, Ferrera VP. A Neural Representation of Categorization Uncertainty in the Human Brain. Neuron 2006, 49: 757-763. PMID: 16504950, DOI: 10.1016/j.neuron.2006.01.032.Peer-Reviewed Original ResearchConceptsCategorization uncertaintyEvent-related functional MRIFundamental cognitive functionFrontoparietal attention networkMedial frontal gyrusStimulus categorizationNeural representationParietal eye fieldsVisual objectsCategorical boundariesAnterior insulaFrontal gyrusCortical substratesAttention networkCognitive functionVentral striatumFunctional MRIPsychophysical functionsEye fieldBrain regionsHuman brainDorsomedial thalamusDiscrete categoriesInsulaThalamic networkStructure-function relationships in the human visual system using DTI, fMRI and visual field testing: pre- and post-operative assessments in patients with anterior visual pathway compression.
Rosiene J, Liu X, Imielinska C, Ferrera J, Bruce J, Hirsch J, D'Ambrosio A. Structure-function relationships in the human visual system using DTI, fMRI and visual field testing: pre- and post-operative assessments in patients with anterior visual pathway compression. 2006, 119: 464-6. PMID: 16404100.Peer-Reviewed Original ResearchConceptsAnterior visual pathway compressionVisual pathway compressionDiffusion tensor imagingFunctional MRIVisual lossVisual recoveryFunctional visual deficitsLarge pituitary lesionsPostoperative visual recoveryProgressive visual lossSignificant visual lossVisual field testingPost-operative assessmentWhite matter projectionsDTI dataVisual field mappingSurgical resectionOptic chiasmPituitary lesionsOptic radiationVisual deficitsFunctional visionPatientsBrain structuresTensor imaging
2005
Responsivity to food stimuli in obese and lean binge eaters using functional MRI
Geliebter A, Ladell T, Logan M, Schweider T, Sharafi M, Hirsch J. Responsivity to food stimuli in obese and lean binge eaters using functional MRI. Appetite 2005, 46: 31-35. PMID: 16364498, DOI: 10.1016/j.appet.2005.09.002.Peer-Reviewed Original ResearchConceptsObese binge eatersBinge eatersAuditory stimuliFood stimuliNon-food stimuliRandom effects group analysisVentral premotor cortexRight premotor areaNon-binge eatersBinge foodsRight-handed womanFMRI scannerConcurrent motorFunctional neuroimagingFunctional MRIPremotor cortexPremotor areasBrain areasStimuliMotor behaviorEatersType foodsIndividual subjectsGroup analysisBinge