2006
Functional Neuroimaging Applications for Assessment and Rehabilitation Planning in Patients With Disorders of Consciousness
Giacino JT, Hirsch J, Schiff N, Laureys S. Functional Neuroimaging Applications for Assessment and Rehabilitation Planning in Patients With Disorders of Consciousness. Archives Of Physical Medicine And Rehabilitation 2006, 87: 67-76. PMID: 17140882, DOI: 10.1016/j.apmr.2006.07.272.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessHigher-order association corticesStudy of patientsRestoration of functionPrimary cortical areasFunctional magnetic resonanceFunctional neuroimaging techniquesFunctional neuroimaging protocolsPotential clinical applicationsPathophysiologic mechanismsPattern of activationPatient characterizationPositron emission tomography activation studyDifferential diagnosisPrognostic assessmentDisconnection syndromeCortical areasAssociation cortexLarge-scale cortical networksPatientsNeuroimaging protocolVegetative stateNeuroimaging techniquesConscious stateCortical networks
2000
An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions
Hirsch J, Ruge M, Kim K, Correa D, Victor J, Relkin N, Labar D, Krol G, Bilsky M, Souweidane M, DeAngelis L, Gutin P. An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions. Neurosurgery 2000, 47: 711. PMID: 10981759, DOI: 10.1097/00006123-200009000-00037.Peer-Reviewed Original ResearchConceptsIntraoperative electrophysiological measurementsVisual field examinationVisual functionHealthy volunteersCentral sulcusVisual cortexFMRI mapsWernicke's areaFunctional magnetic resonance imaging (fMRI) taskDirect cortical stimulationFunctional magnetic resonance imaging (fMRI) procedureBroca's areaField examinationElectrophysiological measurementsSurgical patientsSurgical riskCortical stimulationPreoperative mappingSurgical routeWada testCortical areasElectrophysiological proceduresMagnetic resonance imaging (MRI) proceduresMultiple critical functionsPreoperative map
1997
Distinct cortical areas associated with native and second languages
Kim K, Relkin N, Lee K, Hirsch J. Distinct cortical areas associated with native and second languages. Nature 1997, 388: 171-174. PMID: 9217156, DOI: 10.1038/40623.Peer-Reviewed Original ResearchConceptsSecond languageFunctional magnetic resonance imagingMultiple language functionsLanguage-specific regionsCortical areasEssential human capacitiesFrontal cortical areasLanguage acquisitionNative languageBilingual subjectsMultiple languagesDistinct cortical areasLanguageLanguage functionBroca's areaCortical representationHuman capacityHuman brainHuman cortexAcquisition stageSeparation of activitiesMagnetic resonance imagingResonance imagingFundamental questionsAdulthood