2022
An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions
Crum J, Zhang X, Noah A, Hamilton A, Tachtsidis I, Burgess PW, Hirsch J. An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 669-679. PMID: 35144035, PMCID: PMC9271588, DOI: 10.1016/j.bpsc.2022.01.008.Peer-Reviewed Original ResearchConceptsInterpersonal interactionsPrefrontal cortexRostral prefrontal cortexInferior parietal lobuleMental health interventionsNeural underpinningsDysfunctional cognitionsBrain systemsEcological validityPrefrontal systemsParietal lobuleNeural couplingNeuroimaging techniquesVerbal communicationVerbal interactionClinical neuroscienceMental healthCortexClinical situationsClinical settingClinical tasksClinical interactionsParadigmHealth interventionsCognition
2018
Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment
Fertuck EA, Grinband J, Mann JJ, Hirsch J, Ochsner K, Pilkonis P, Erbe J, Stanley B. Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment. NeuroImage Clinical 2018, 21: 101616. PMID: 30639176, PMCID: PMC6411618, DOI: 10.1016/j.nicl.2018.101616.Peer-Reviewed Original ResearchFunctional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation
Galgano J, Pantazatos S, Allen K, Yanagihara T, Hirsch J. Functional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation. Brain Research 2018, 1707: 184-189. PMID: 30500402, PMCID: PMC7434632, DOI: 10.1016/j.brainres.2018.11.040.Peer-Reviewed Original ResearchConceptsPeriaqueductal gray regionPsychophysiological interaction analysisFunctional connectivityDiffusion tensor imaging (DTI) analysisTrend-level evidenceNeural mechanismsBilateral auditory corticesGreater functional connectivityAmygdala couplingWhole-brain resultsDorsomedial prefrontal cortexLimbic systemMotor areaAmygdala clustersAuditory cortexLaryngeal musculatureHealthy adultsPrefrontal cortexNeuroimaging studiesNeural activityVoice disordersStructural connectivityGray regionCortexMovement paradigm
2017
Neurofeedback-based functional near-infrared spectroscopy upregulates motor cortex activity in imagined motor tasks
Lapborisuth P, Zhang X, Noah A, Hirsch J. Neurofeedback-based functional near-infrared spectroscopy upregulates motor cortex activity in imagined motor tasks. Neurophotonics 2017, 4: 021107-021107. PMID: 28680906, PMCID: PMC5482291, DOI: 10.1117/1.nph.4.2.021107.Peer-Reviewed Original Research
2015
Motor learning and modulation of prefrontal cortex: an fNIRS assessment
Ono Y, Noah JA, Zhang X, Nomoto Y, Suzuki T, Shimada S, Tachibana A, Bronner S, Hirsch J. Motor learning and modulation of prefrontal cortex: an fNIRS assessment. Journal Of Neural Engineering 2015, 12: 066004. PMID: 26401727, DOI: 10.1088/1741-2560/12/6/066004.Peer-Reviewed Original ResearchConceptsDance video gameHemodynamic responsePrefrontal cortexMotor tasksMotor learningMotor performanceSpecific rehabilitation programPrefrontal hemodynamic responsesBaseline patternsHealthy young adultsTraining-induced changesComplex motor tasksRehabilitation programYoung adultsRegression analysisCortexRegression modelsAuditory cuesNovice playersSensitive indicatorResponseParticipants
2010
The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood
Grinband J, Savitskaya J, Wager TD, Teichert T, Ferrera VP, Hirsch J. The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood. NeuroImage 2010, 57: 303-311. PMID: 21168515, PMCID: PMC3114292, DOI: 10.1016/j.neuroimage.2010.12.027.Peer-Reviewed Original ResearchA translational bridge between mouse and human models of learned safety
Pollak DD, Rogan MT, Egner T, Perez DL, Yanagihara TK, Hirsch J. A translational bridge between mouse and human models of learned safety. Annals Of Medicine 2010, 42: 127-134. PMID: 20121549, DOI: 10.3109/07853890903583666.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexNeural circuitryPrefrontal cortexAnimal experimentsTranslational bridgeFunctional magnetic resonanceParallel groupSafety signalsPupillary constrictionNoxious stimuliUnderlying neural circuitryHuman studiesExperimental animalsHuman modelNeural connectionsAnimal protocolsMiceCaudate responseNeutral stimuliNeural responsesNeural substratesDiffusion tensorAmygdalaCortexMolecular mechanisms
2009
11C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls
Goland R, Freeby M, Parsey R, Saisho Y, Kumar D, Simpson N, Hirsch J, Prince M, Maffei A, Mann JJ, Butler PC, Van Heertum R, Leibel RL, Ichise M, Harris PE. 11C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls. Journal Of Nuclear Medicine 2009, 50: 382-389. PMID: 19223416, PMCID: PMC3629294, DOI: 10.2967/jnumed.108.054866.Peer-Reviewed Original ResearchConceptsBeta-cell massType 1 diabetesInsulin secretionVMAT2 bindingRenal cortexLong-Standing Type 1 DiabetesType 2 vesicular monoamine transporterFunctional binding capacityBinding capacityVesicular monoamine transporterInsulin secretion measurementsHealthy controlsHigh nonspecific bindingHealthy subjectsPatientsPreclinical experimentsControl valuesHuman pancreasDiabetesPancreasSecretion measurementsMonoamine transportersReference tissueCortexVMAT2
2008
Comparison of contrast-response functions from multifocal visual-evoked potentials (mfVEPs) and functional MRI responses
Park JC, Zhang X, Ferrera J, Hirsch J, Hood DC. Comparison of contrast-response functions from multifocal visual-evoked potentials (mfVEPs) and functional MRI responses. Journal Of Vision 2008, 8: 8-8. PMID: 19146350, PMCID: PMC2987574, DOI: 10.1167/8.10.8.Peer-Reviewed Original ResearchConceptsBOLD fMRI responsesMultifocal visual-evoked potentialsContrast response functionsVisual-evoked potentialsFMRI responsesNeural activityFunctional MRI responsesBOLD fMRI signalMonocular mfVEPRetinotopic mapMRI responseV1 areaPattern stimuliBOLD responseFMRI signalsSame stimuliSubjectsResponseV1MfVEPStimuliMfVEPsCortexA case of locked-in syndrome complicated by central deafness
Smart CM, Giacino JT, Cullen T, Rodriguez Moreno D, Hirsch J, Schiff ND, Gizzi M. A case of locked-in syndrome complicated by central deafness. Nature Reviews Neurology 2008, 4: 448-453. PMID: 18506168, DOI: 10.1038/ncpneuro0823.Peer-Reviewed Original Research
2007
Repeated Exposure to Media Violence Is Associated with Diminished Response in an Inhibitory Frontolimbic Network
Kelly CR, Grinband J, Hirsch J. Repeated Exposure to Media Violence Is Associated with Diminished Response in an Inhibitory Frontolimbic Network. PLOS ONE 2007, 2: e1268. PMID: 18060062, PMCID: PMC2092389, DOI: 10.1371/journal.pone.0001268.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingRight lateral orbitofrontal cortexMagnetic resonance imagingLateral orbitofrontal cortexDiminished responsivenessDiminished responseShort-term exposureResonance imagingFrontolimbic networkOrbitofrontal cortexCortical networksNovel findingsExposureResponseCortex
2006
Predictive Codes for Forthcoming Perception in the Frontal Cortex
Summerfield C, Egner T, Greene M, Koechlin E, Mangels J, Hirsch J. Predictive Codes for Forthcoming Perception in the Frontal Cortex. Science 2006, 314: 1311-1314. PMID: 17124325, DOI: 10.1126/science.1132028.Peer-Reviewed Original ResearchConceptsFrontal cortexIncoming sensory informationMedial frontal cortexPresence of facesPerceptual ambiguityPerceptual decisionsSensory evidenceNeural representationVisual objectsSensory environmentVisual areasPredictive codingSensory informationPredictive codePerceptionCortexFaceHuman subjectsBrainObserved evidenceDecisionsAmbiguityRepresentationEvidenceObjectsResolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
Etkin A, Egner T, Peraza DM, Kandel ER, Hirsch J. Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala. Neuron 2006, 51: 871-882. PMID: 16982430, DOI: 10.1016/j.neuron.2006.07.029.Peer-Reviewed Original ResearchConceptsRostral anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingCingulate cortexEmotional conflictAmygdalar activityRostral cingulate cortexMagnetic resonance imagingDorsolateral prefrontal cortexRostral cingulateResonance imagingPrefrontal cortexModulating activityCortexConflict taskSalient stimuliNeural activityNeural mechanismsMental functioningActivationConflictActivityAmygdalaNeocortical Connectivity during Episodic Memory Formation
Summerfield C, Greene M, Wager T, Egner T, Hirsch J, Mangels J. Neocortical Connectivity during Episodic Memory Formation. PLOS Biology 2006, 4: e128. PMID: 16605307, PMCID: PMC1436028, DOI: 10.1371/journal.pbio.0040128.Peer-Reviewed Original ResearchConceptsEpisodic encodingPerceptual informationEpisodic memory tracesLeft dorsolateral prefrontal cortexNew episodic memoriesEpisodic memory formationFunctional magnetic resonanceDorsolateral prefrontal cortexExtrastriate visual cortexEpisodic memoryMemory tracesBrain mechanismsSensory representationsVisual stimuliPrefrontal cortexConnectivity analysisMemory formationVisual cortexNeocortical connectivityEncodingHemodynamic signalsCortexReliable predictorMemorySelective response
1999
Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping
Ruge M, Victor J, Hosain S, Correa D, Relkin N, Tabar V, Brennan C, Gutin P, Hirsch J. Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping. Stereotactic And Functional Neurosurgery 1999, 72: 95-102. PMID: 10853058, DOI: 10.1159/000029706.Peer-Reviewed Original ResearchConceptsDirect cortical stimulationIntraoperative electrophysiologyCortical stimulationSensorimotor cortexIntraoperative language mappingFunctional magnetic resonance imagingMagnetic resonance imagingSSEP recordingsLocalization of functionMotor cortexIntraoperative localizationPreoperative toolResonance imagingLanguage mappingCortexWernicke's areaElectrophysiologyFMRIPresent studyStimulationSensorimotor mappingConcordancePatientsBroca
1998
Representation of nociceptive stimuli in primary sensory cortex
Berman H, Kim K, Talati A, Hirsch J. Representation of nociceptive stimuli in primary sensory cortex. Neuroreport 1998, 9: 4179-4187. PMID: 9926870, DOI: 10.1097/00001756-199812210-00033.Peer-Reviewed Original ResearchConceptsHuman primary sensorimotor cortexPrimary sensorimotor cortexPrimary somatosensory cortexPrimary sensory cortexRight-handed subjectsFoot stimulationSensorimotor cortexSomatosensory cortexNociceptive stimuliSensory cortexSomatotopic mappingCortical activityPenfield's homunculusCold sensationRight handCortexSensory processingTactile stimuliThermal modalitiesFootActivated regionsSensationStimuliBody parts
1997
Fast and Localized Event-Related Optical Signals (EROS) in the Human Occipital Cortex: Comparisons with the Visual Evoked Potential and fMRI
Gratton G, Fabiani M, Corballis P, Hood D, Goodman-Wood M, Hirsch J, Kim K, Friedman D, Gratton E. Fast and Localized Event-Related Optical Signals (EROS) in the Human Occipital Cortex: Comparisons with the Visual Evoked Potential and fMRI. NeuroImage 1997, 6: 168-180. PMID: 9344821, DOI: 10.1006/nimg.1997.0298.Peer-Reviewed Original Research
1995
Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imaging.
Hirsch J, DeLaPaz R, Relkin N, Victor J, Kim K, Li T, Borden P, Rubin N, Shapley R. Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imaging. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 6469-6473. PMID: 7604015, PMCID: PMC41539, DOI: 10.1073/pnas.92.14.6469.Peer-Reviewed Original ResearchConceptsPerceptual grouping operationsIllusory contoursSpecific brain regionsGrouping operationsFunctional magnetic resonance imagingIllusory contour perceptionBrain regionsFunctional magnetic resonanceHuman visual cortexHuman visual systemContour perceptionNeural basisPerceptual contoursVisual stimuliRight hemisphereExtrastriate cortexHuman visionKanizsa squareVisual systemActivated regionsVisual stimulationVisual cortexSimilar inducersContinuous contourCortex