2007
The Calcium-Sensing Receptor Regulates Plasma Membrane Calcium Adenosine Triphosphatase Isoform 2 Activity in Mammary Epithelial Cells: A Mechanism for Calcium-Regulated Calcium Transport into Milk
VanHouten JN, Neville MC, Wysolmerski JJ. The Calcium-Sensing Receptor Regulates Plasma Membrane Calcium Adenosine Triphosphatase Isoform 2 Activity in Mammary Epithelial Cells: A Mechanism for Calcium-Regulated Calcium Transport into Milk. Endocrinology 2007, 148: 5943-5954. PMID: 17823248, PMCID: PMC7108505, DOI: 10.1210/en.2007-0850.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological TransportBlotting, WesternCalciumCells, CulturedEpithelial CellsFemaleFluorescent Antibody TechniqueGadoliniumIsoenzymesLactationMammary Glands, AnimalMiceMice, Inbred BALB CMicroscopy, ImmunoelectronMilkMilk ProteinsMutationOligonucleotide Array Sequence AnalysisPlasma Membrane Calcium-Transporting ATPasesReceptors, Calcium-SensingReverse Transcriptase Polymerase Chain ReactionConceptsPlasma membrane calcium ATPase isoform 2Mammary epithelial cellsMouse mammary epithelial cellsEpH4 mouse mammary epithelial cellsEpithelial cellsGenome-wide screening strategyApical plasma membraneATPase activityPotential downstream targetsATPase isoform 2Mouse mammary glandPlasma membrane preparationsDeafwaddler miceTransepithelial calcium transportPlasma membraneDownstream targetsGene knockdownPMCA2 activityCalcium transportIsoform 2Calcium-dependent ATPase activityCell membraneCultured primaryCalcium-sensing receptorPMCA2 expression
2001
Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas
VanHouten J, Asch H, Asch B. Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas. Oncogene 2001, 20: 5366-5372. PMID: 11536049, DOI: 10.1038/sj.onc.1204701.Peer-Reviewed Original ResearchMeSH KeywordsActinsAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernBlotting, WesternCloning, MolecularConcanavalin ADNA, ComplementaryEndoplasmic ReticulumExtracellular MatrixHumansMammary Neoplasms, AnimalMiceMice, Inbred BALB CMicroscopy, FluorescenceMicrotubulesMolecular Sequence DataOpen Reading FramesPhosphoric Monoester HydrolasesPrecipitin TestsProtein Structure, TertiaryRNA, MessengerTransfectionTumor Cells, CulturedConceptsN-terminal BTB domainMouse mammary epithelial cellsPlacental-specific genesMammary epithelial cellsKb ORFBTB domainKelch familyProtein bindsActin filamentsEndoplasmic reticulumMouse mammary tumorsBreast cell linesHuman breast cell linesExtracellular matrixProteinCell linesEpithelial cellsMalignant progressionTranscriptsCellular structureMicrofilamentsActinGrowth rateMammary tumorsExpression