2020
Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers
Tollenaar L, Slaghekke F, Lewi L, Ville Y, Lanna M, Weingertner A, Ryan G, Arévalo S, Khalil A, Brock C, Klaritsch P, Hecher K, Gardener G, Bevilacqua E, Kostyukov K, Bahtiyar M, Kilby M, Tiblad E, Oepkes D, Lopriore E, Middeldorp J, Haak M, Klumper F, Akkermans J, Delagrange H, Pandya V, Faiola S, Favre R, Hobson S, Rodo C, Thilaganathan B, Papanna R, Greimel P, de Sousa M, Carlin A, Gladkova K, Copel J. Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers. Ultrasound In Obstetrics And Gynecology 2020, 56: 378-387. PMID: 32291846, PMCID: PMC7497010, DOI: 10.1002/uog.22042.Peer-Reviewed Original ResearchConceptsTwin anemia-polycythemia sequenceFetal therapy centersMonochorionic twin pregnanciesPost-laser twin anemia-polycythemia sequenceExpectant management groupSevere neonatal morbidityIntrauterine transfusionExpectant managementPerinatal mortalitySelective feticideTwin pregnanciesLaser surgeryNeonatal morbidityDelivery groupIUT groupDiagnosis of TAPSMiddle cerebral artery peak systolic velocityFetal middle cerebral artery peak systolic velocityBirth intervalLaser surgery groupProlongation of pregnancyTherapy CenterPeak systolic velocityLarge international cohortMedian diagnosis
1997
The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus
d'Ancona R, Rahman F, Ozcan T, Copel J, Mari G. The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus. Ultrasound In Obstetrics And Gynecology 1997, 10: 333-337. PMID: 9444047, DOI: 10.1046/j.1469-0705.1997.10050333.x.Peer-Reviewed Original ResearchMeSH KeywordsAnemiaBlood Flow VelocityBlood Transfusion, IntrauterineFemaleFetal DiseasesFetusHumansPortal VeinPregnancyPulsatile FlowUltrasonography, PrenatalConceptsFlow velocity waveformsPortal venous systemAnemic fetusesVelocity waveformsPortal hypertensionIntravascular transfusionPortal veinVenous systemNormal fetusesIntravascular blood transfusionNon-pulsatile flowBlood transfusionRhesus alloimmunizationGestational agePulsatile patternTransfusionFetusesPresence of pulsatilityHypertensionIncreased numberCardiac cyclePulsatileVeinAlloimmunizationUteroIncrease of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. PMID: 9260116, DOI: 10.1002/(sici)1520-6661(199707/08)6:4<206::aid-mfm3>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosis
1993
Erythropoietin in human fetuses with immune hemolytic anemia and hydrops fetalis.
Moya F, Grannum P, Widness J, Clemons G, Copel J, Hobbins J. Erythropoietin in human fetuses with immune hemolytic anemia and hydrops fetalis. Obstetrics And Gynecology 1993, 82: 353-8. PMID: 8355933.Peer-Reviewed Original ResearchMeSH KeywordsAnemia, Hemolytic, AutoimmuneBlood Transfusion, IntrauterineErythropoietinFetal BloodFetal DiseasesGestational AgeHemoglobinsHumansHydrops FetalisRegression AnalysisRh IsoimmunizationConceptsRh isoimmunizationGestational agePlasma erythropoietinWeeks' gestationElective cesareanControl fetusesImmune hemolytic anemiaUmbilical cord plasmaHigh erythropoietin levelsUmbilical cord bloodCord plasmaLower hemoglobinInverse associationTerm fetusesCord bloodErythropoietin levelsHemolytic anemiaErythropoietin measurementsLate gestationHuman fetusesGestationFetusesIsoimmunizationAnemiaHemoglobin
1991
Interventional procedures in obstetrics
Copel J, Grannum P, Hobbins J. Interventional procedures in obstetrics. Seminars In Roentgenology 1991, 26: 87-94. PMID: 2006436, DOI: 10.1016/0037-198x(91)90042-m.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1990
Invasive Fetal Procedures
Grannum P, Copel J. Invasive Fetal Procedures. Radiologic Clinics Of North America 1990, 28: 217-226. PMID: 2404303, DOI: 10.1016/s0033-8389(22)01230-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsBiopsyBlood Specimen CollectionBlood Transfusion, IntrauterineFemaleFetal BloodFetal DiseasesFetoscopyHumansPregnancyUltrasonography
1989
Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion
Copel J, Grannum P, Green J, Belanger K, Hanna N, Jaffe C, Hobbins J, Kleinman C. Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion. American Journal Of Obstetrics And Gynecology 1989, 161: 361-365. PMID: 2504042, DOI: 10.1016/0002-9378(89)90520-6.Peer-Reviewed Original ResearchConceptsCardiac outputAnemic fetusesIsoimmunized pregnanciesCombined ventricular outputDoppler echocardiographic studyFetal cardiac outputHigh output stateHigh cardiac outputIntravascular intrauterine transfusionSevere isoimmunizationCardiac indexIntrauterine transfusionIntravascular transfusionWeeks' gestationVentricular outputDoppler assessmentAge-specific normsControl fetusesHydrops fetalisControl groupMechanisms of developmentFetusesUnaffected fetusesTransfusionPregnancy
1988
Diagnostic fetal umbilical blood sampling in the management of isoimmunization
Reece E, Copel J, Scioscia A, Grannum P, DeGennaro N, Hobbins J. Diagnostic fetal umbilical blood sampling in the management of isoimmunization. American Journal Of Obstetrics And Gynecology 1988, 159: 1057-1062. PMID: 3142263, DOI: 10.1016/0002-9378(88)90412-7.Peer-Reviewed Original ResearchConceptsAntigen-positive fetusesFetal hemolytic diseaseFetal umbilical bloodManagement of isoimmunizationEarlier gestational ageMultiple invasive proceduresIsoimmunized pregnanciesFetal anemiaAntigen statusGestational ageUmbilical bloodHemolytic diseaseFetal bloodInvasive proceduresCurrent managementFetusesPreliminary reportPregnancyIsoimmunizationDiseaseManagement protocolDiagnosisBloodLittle riskTreatmentPrevention of Rh isoimmunization and treatment of the compromised fetus.
Grannum P, Copel J. Prevention of Rh isoimmunization and treatment of the compromised fetus. Seminars In Perinatology 1988, 12: 324-35. PMID: 3146812.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBlood Transfusion, IntrauterineErythroblastosis, FetalFemaleFetal DeathHumansHydrops FetalisInfant, NewbornPregnancyRh IsoimmunizationConceptsFetal liver functionIntrauterine intravascular transfusionReversal of hydropsCorrection of anemiaWeeks of gestationSevere erythroblastosis fetalisNeonatal exchange transfusionProblems of prematurityNeonatal morbidityErythroblastosis fetalisIntravascular transfusionRh isoimmunizationExchange transfusionLiver functionFetal vasculatureIntravascular treatmentSevere diseaseTreatment teamPrompt correctionCentral veinTreatment centersTransfusionDifficult procedureTreatmentIsoimmunizationPulsed Doppler flow-velocity waveforms before and after intrauterine intravascular transfusion for severe erythroblastosis fetalis
Copel J, Grannum P, Belanger K, Green J, Hobbins J. Pulsed Doppler flow-velocity waveforms before and after intrauterine intravascular transfusion for severe erythroblastosis fetalis. American Journal Of Obstetrics And Gynecology 1988, 158: 768-774. PMID: 2966585, DOI: 10.1016/0002-9378(88)90070-1.Peer-Reviewed Original ResearchMeSH KeywordsBlood Transfusion, IntrauterineErythroblastosis, FetalFemaleFetal BloodGestational AgeHematocritHumansInfant, NewbornModels, BiologicalPregnancyPrenatal DiagnosisPrognosisRheologyConceptsLate transfusionDoppler flow velocity waveformsIntrauterine intravascular transfusionFlow velocity waveformsSevere erythroblastosis fetalisFirst transfusionIntrauterine transfusionSubsequent transfusionsErythroblastosis fetalisIntravascular transfusionIsoimmunized pregnanciesDoppler studiesMaternal circulationDoppler ultrasoundTransfusionNormal fetusesHematocrit changesLack of changeHematocritDoppler parametersFetusesRapid volumeHydropsPregnancyFetalisThe reversal of hydrops fetalis by intravascular intrauterine transfusion in severe isoimmune fetal anemia
Grannum P, Copel J, Moya F, Scioscia A, Robert J, Winn H, Coster B, Burdine C, Hobbins J. The reversal of hydrops fetalis by intravascular intrauterine transfusion in severe isoimmune fetal anemia. American Journal Of Obstetrics And Gynecology 1988, 158: 914-919. PMID: 3284364, DOI: 10.1016/0002-9378(88)90094-4.Peer-Reviewed Original ResearchConceptsGm/dlIntrauterine intravascular transfusionIntravascular transfusionHematocrit levelsSurvival rateSevere respiratory distress syndromeReversal of hydropsOverall survival rateRespiratory distress syndromeTime of referralIntravascular intrauterine transfusionSevere erythroblastosis fetalisTotal proteinIntrauterine transfusionNeonatal morbidityErythroblastosis fetalisHydropic fetusesDistress syndromeFetal anemiaExchange transfusionNeonatal deathIntraperitoneal transfusionSevere erythroblastosisNewborn periodIntravascular treatmentThe use of intravenous pancuronium bromide to produce fetal paralysis during intravascular transfusion
Copel J, Grannum P, Harrison D, Hobbins J. The use of intravenous pancuronium bromide to produce fetal paralysis during intravascular transfusion. American Journal Of Obstetrics And Gynecology 1988, 158: 170-171. PMID: 3337166, DOI: 10.1016/0002-9378(88)90804-6.Peer-Reviewed Original ResearchMeSH KeywordsBlood Transfusion, IntrauterineFemaleFetal MovementHumansInfusions, IntravenousPancuroniumParalysisPregnancy