2001
Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient
Verheijen P, Lisowski L, Stoutenbeek P, Hitchcock J, Brenner J, Copel J, Kleinman C, Meijboom E, Bennink G. Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient. Journal Of Thoracic And Cardiovascular Surgery 2001, 121: 798-803. PMID: 11279423, DOI: 10.1067/mtc.2001.112825.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseLower base excessHeart obstructionMetabolic acidosisBase excessDuctus-dependent congenital heart diseasePrenatal diagnosisPostnatal diagnosisImproved long-term outcomesGroup of patientsArterial blood gasesLong-term outcomesCause of deathHigher lactate levelsDays of lifePrevention of acidosisSignificant differencesBiventricular repairPreoperative conditionCerebral damageRetrospective studySurgical outcomesPreoperative acidosisBlood gases
1990
Does the umbilical artery systolic/diastolic ratio reflect flow or acidosis? An umbilical artery Doppler study of fetal sheep
Copel J, Schlafer D, Wentworth R, Belanger K, Kreitzer L, Hobbins J, Nathanielsz P. Does the umbilical artery systolic/diastolic ratio reflect flow or acidosis? An umbilical artery Doppler study of fetal sheep. American Journal Of Obstetrics And Gynecology 1990, 163: 751-756. PMID: 2206067, DOI: 10.1016/0002-9378(90)91062-h.Peer-Reviewed Original ResearchConceptsSystolic/diastolic ratioUmbilical artery systolic/diastolic ratioDiastolic ratioFetal sheepNormal systolic/diastolic ratioUmbilical artery Doppler studiesArterial blood gas levelsBlood gas levelsAcid-base statusArtery embolizationFetal oxygenationPlacental perfusionMaternal anesthesiaPlacental embolizationAcute modelDoppler studiesThird injectionUmbilical flowFourth injectionSubsequent embolizationDays gestationFirst injectionSecond injectionEmbolizationGreater magnitude change