2001
Ratio of nuchal thickness to humerus length for Down syndrome detection
Bahado-Singh R, Oz U, Hsu C, Deren O, Copel J, Mahoney M. Ratio of nuchal thickness to humerus length for Down syndrome detection. American Journal Of Obstetrics And Gynecology 2001, 184: 1284-1288. PMID: 11349203, DOI: 10.1067/mob.2001.113878.Peer-Reviewed Original ResearchConceptsDown syndrome riskHigh-risk groupMaternal ageSyndrome riskNuchal thicknessDown syndromeDown syndrome detectionStudy populationIndividual Down's syndrome riskMean gestational ageOverall study populationAge-related riskHumerus lengthSyndrome detectionDown syndrome casesDown's syndrome likelihood ratiosGestational ageProspective dataHealthy groupGross anomaliesNormal fetusesSyndrome casesBiparietal diameterAmniocentesis casesFetal population
2000
Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anemia Due to Maternal Red-Cell Alloimmunization
Mari G, Deter R, Carpenter R, Rahman F, Zimmerman R, Moise K, Dorman K, Ludomirsky A, Gonzalez R, Gomez R, Oz U, Detti L, Copel J, Bahado-Singh R, Berry S, Martinez-Poyer J, Blackwell S. Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anemia Due to Maternal Red-Cell Alloimmunization. New England Journal Of Medicine 2000, 342: 9-14. PMID: 10620643, DOI: 10.1056/nejm200001063420102.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityBlood Group IncompatibilityCordocentesisErythroblastosis, FetalErythrocytesFemaleFetal BloodGestational AgeHemoglobinsHumansInfant, NewbornIsoantibodiesMiddle Cerebral ArteryPregnancyPregnancy Complications, HematologicProspective StudiesReference ValuesRh IsoimmunizationROC CurveSensitivity and SpecificityUltrasonography, Doppler, PulsedUltrasonography, PrenatalConceptsMaternal red cell alloimmunizationRed cell alloimmunizationMiddle cerebral arterySystolic blood flowCerebral arteryBlood flowSevere anemiaFetal anemiaDoppler ultrasonographyNormal fetusesHemoglobin concentrationFetal middle cerebral arteryPeak velocityFetal hemoglobin concentrationAbsence of hydropsPeak systolic velocityGestational ageModerate anemiaSystolic velocityHemoglobin valuesMild anemiaInvasive techniquesAlloimmunizationAnemiaArtery
1999
Gestational age standardized nuchal thickness values for estimating mid‐trimester Down's syndrome risk
Bahado‐Singh R, Oz U, Kovanci E, Deren O, Feather M, Hsu C, Copel J, Mahoney M. Gestational age standardized nuchal thickness values for estimating mid‐trimester Down's syndrome risk. The Journal Of Maternal-Fetal Medicine 1999, 8: 37-43. PMID: 10090488, DOI: 10.1002/(sici)1520-6661(199903/04)8:2<37::aid-mfm1>3.0.co;2-p.Peer-Reviewed Original ResearchA new splenic artery Doppler velocimetric index for prediction of severe fetal anemia associated with Rh alloimmunization
Bahado-Singh R, Oz U, Deren O, Pirhonen J, Kovanci E, Copel J, Onderoglu L. A new splenic artery Doppler velocimetric index for prediction of severe fetal anemia associated with Rh alloimmunization. American Journal Of Obstetrics And Gynecology 1999, 180: 49-54. PMID: 9914577, DOI: 10.1016/s0002-9378(99)70148-1.Peer-Reviewed Original ResearchConceptsMain splenic arterySevere fetal anemiaSevere anemiaHemoglobin deficitFetal anemiaSplenic arteryGestational ageDoppler velocimetric indicesDevelopment of hydropsNew Doppler indexVelocimetric indicesCase patientsDoppler indicesRh alloimmunizationRh sensitizationHealthy fetusesAnemiaFalse positive rateNoninvasive predictionDiastolic phaseAnemia detectionDoppler velocimetrySignificant correlationArteryCordocentesis
1998
Elevated amniotic fluid levels of leukemia inhibitory factor, interleukin 6, and interleukin 8 in intra-amniotic infection
Hsu C, Meaddough E, Aversa K, Hong S, Lu L, Jones D, Copel J. Elevated amniotic fluid levels of leukemia inhibitory factor, interleukin 6, and interleukin 8 in intra-amniotic infection. American Journal Of Obstetrics And Gynecology 1998, 179: 1267-1270. PMID: 9822513, DOI: 10.1016/s0002-9378(98)70144-9.Peer-Reviewed Original ResearchConceptsIntra-amniotic infectionAmniotic fluid levelsLeukemia inhibitory factorInterleukin-6Interleukin-8Fluid levelsInhibitory factorCreatinine levelsPregnant womenPositive amniotic fluid culture resultsAmniotic fluid creatinine levelsElevated amniotic fluid levelsAmniotic fluid culture resultsAmniotic fluid testsEnzyme-linked immunoassayPreterm contractionsPremature rupturePrognostic importanceLeukocyte countSignificant elevationAmniotic fluidMedian levelsCulture resultsInfectionGram stainArterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome
Ozcan T, Sbracia M, d'Ancona R, Copel J, Mari G. Arterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome. Ultrasound In Obstetrics And Gynecology 1998, 12: 39-44. PMID: 9697283, DOI: 10.1046/j.1469-0705.1998.12010039.x.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityCerebral ArteriesFemaleFetal Growth RetardationFetusHumansInfant, NewbornPregnancyPregnancy OutcomePrognosisPulsatile FlowReference ValuesSensitivity and SpecificitySignal Processing, Computer-AssistedSurvival RateUltrasonography, Doppler, ColorUltrasonography, PrenatalUmbilical ArteriesUmbilical VeinsConceptsAdverse outcome parametersAdverse perinatal outcomesGrowth-restricted fetusesOutcome parametersApgar scorePerinatal outcomesDuctus venosusPerinatal deathNeonatal intensive care unitSevere intrauterine growth restrictionDuctus venosus Doppler velocimetryAbnormal Doppler velocimetryVenous Doppler velocimetryVenous Doppler waveformsRespiratory distress syndromeMiddle cerebral arteryRetinopathy of prematurityIntensive care unitIntrauterine growth restrictionDays of lifeOnly significant parameterApgar valuesPeriventricular leukomalaciaDistress syndromeFetal demise
1997
Antepartum and postpartum thrombomodulin levels in preeclamptic and normotensive pregnancies.
Hsu C, Copel J, Chan D. Antepartum and postpartum thrombomodulin levels in preeclamptic and normotensive pregnancies. Reproductive Sciences 1997, 4: 135-7. PMID: 9258877, DOI: 10.1016/s1071-5576(97)00012-9.Peer-Reviewed Original Research
1996
Is the fetal brain‐sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant?
Mari G, Abuhamad A, Keller M, Verpairojkit B, Ment L, Copel J. Is the fetal brain‐sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant? Ultrasound In Obstetrics And Gynecology 1996, 8: 329-332. PMID: 8978007, DOI: 10.1046/j.1469-0705.1996.08050329.x.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery pulsatility indexCerebral artery pulsatility indexBrain-sparing effectArtery pulsatility indexIntrauterine growth restrictionIntraventricular hemorrhagePulsatility indexPreterm laborAntenatal exposureGestational ageMean birth weightNeonatal intraventricular hemorrhageRespiratory distress syndromeMiddle cerebral arteryFirst postnatal weekApgar scoreCesarean sectionNecrotizing enterocolitisPreterm infantsBrain sparingDistress syndromeWeeks' gestationCerebral arteryIUGR fetusesDoppler studiesNicked free β-subunit of human chorionic gonadotropin: A potential new marker for Down syndrome screening
Rotmensch S, Liberati M, Kardana A, Copel J, Ben-Rafael Z, Cole L. Nicked free β-subunit of human chorionic gonadotropin: A potential new marker for Down syndrome screening. American Journal Of Obstetrics And Gynecology 1996, 174: 609-611. PMID: 8623792, DOI: 10.1016/s0002-9378(96)70435-0.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotropinDown syndrome screeningChorionic gonadotropinSyndrome pregnanciesSyndrome screeningFree beta subunitMaternal serum levelsDown syndrome pregnanciesPotential new markerFree β-subunitSerum levelsNormal controlsSensitive markerImmunoenzymometric assaySerum specimensDown syndromeGonadotropinMean levelsNew markersPreliminary dataMedianPregnancyCase levelMarkersΒ-subunit
1995
Abdominal venous system in the normal fetus.
Mari G, Uerpairojkit B, Copel J. Abdominal venous system in the normal fetus. Obstetrics And Gynecology 1995, 86: 729-33. PMID: 7566838, DOI: 10.1016/0029-7844(95)00264-r.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenBlood Flow VelocityFemaleFetusHumansPregnancyReference ValuesUltrasonography, DopplerVeinsConceptsFlow velocity waveformsInferior vena cavaAbdominal venous systemUmbilical sinusNormal fetusesVena cavaPortal veinVenous systemVelocity waveformsDuctus venosusSplenic veinHepatic veinUmbilical veinCommon iliac veinLeft hepatic veinAdrenal veinWeeks' gestationRenal veinIliac veinAnterior divisionPosterior divisionMonophasic patternFetusesCavaBiphasic pattern