2000
Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anemia Due to Maternal Red-Cell Alloimmunization
Mari G, Deter R, Carpenter R, Rahman F, Zimmerman R, Moise K, Dorman K, Ludomirsky A, Gonzalez R, Gomez R, Oz U, Detti L, Copel J, Bahado-Singh R, Berry S, Martinez-Poyer J, Blackwell S. Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anemia Due to Maternal Red-Cell Alloimmunization. New England Journal Of Medicine 2000, 342: 9-14. PMID: 10620643, DOI: 10.1056/nejm200001063420102.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityBlood Group IncompatibilityCordocentesisErythroblastosis, FetalErythrocytesFemaleFetal BloodGestational AgeHemoglobinsHumansInfant, NewbornIsoantibodiesMiddle Cerebral ArteryPregnancyPregnancy Complications, HematologicProspective StudiesReference ValuesRh IsoimmunizationROC CurveSensitivity and SpecificityUltrasonography, Doppler, PulsedUltrasonography, PrenatalConceptsMaternal red cell alloimmunizationRed cell alloimmunizationMiddle cerebral arterySystolic blood flowCerebral arteryBlood flowSevere anemiaFetal anemiaDoppler ultrasonographyNormal fetusesHemoglobin concentrationFetal middle cerebral arteryPeak velocityFetal hemoglobin concentrationAbsence of hydropsPeak systolic velocityGestational ageModerate anemiaSystolic velocityHemoglobin valuesMild anemiaInvasive techniquesAlloimmunizationAnemiaArtery
1997
Circulating Thrombomodulin Levels and Clinical Correlates in Pregnant Diabetics
Magriples U, Hsu C, Chan D, Nickless N, Copel J. Circulating Thrombomodulin Levels and Clinical Correlates in Pregnant Diabetics. American Journal Of Perinatology 1997, 14: 605-608. PMID: 9605246, DOI: 10.1055/s-2008-1040762.Peer-Reviewed Original ResearchMeSH KeywordsAdultDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansPregnancyPregnancy Complications, HematologicPregnancy in DiabeticsProspective StudiesThrombomodulinConceptsDuration of diabetesPregnant diabeticsClinical correlatesGroup 1Prospective cohort studyInsulin-dependent diabetesWeeks of gestationGestational diabetesCohort studyDiabetic pregnanciesSerum creatinineRenal diseaseThrombomodulin levelsEndothelial damageWhite classificationUnderwent determinationTM levelsDiabetesHbA1cDiabeticsThrombomodulinShort-term controlSignificant differencesDurationCorrelatesIncrease of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. PMID: 9260116, DOI: 10.1002/(sici)1520-6661(199707/08)6:4<206::aid-mfm3>3.0.co;2-n.Peer-Reviewed Original ResearchMeSH KeywordsAnemiaBlood Flow VelocityBlood Transfusion, IntrauterineCerebral ArteriesEmbryonic and Fetal DevelopmentFemaleHematocritHumansPregnancyPregnancy Complications, HematologicRh IsoimmunizationUltrasonography, DopplerConceptsMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosis
1995
Management of the Rh-Sensitizeo Mother
Gollin Y, Copel J. Management of the Rh-Sensitizeo Mother. Clinics In Perinatology 1995, 22: 545-559. PMID: 8521681, DOI: 10.1016/s0095-5108(18)30268-9.ChaptersMeSH KeywordsAnemiaFemaleFetal DiseasesHumansPregnancyPregnancy Complications, HematologicRh IsoimmunizationRisk FactorsConceptsRh immune globulinManagement of complicationsRh D typingEarly referralIntrauterine transfusionImmune globulinRh isoimmunizationTertiary centerAnemic fetusesNeonatal careFetal bloodInvasive techniquesLung maturityPrompt identificationD typingClinical situationsOptimal managementFetusesMothersTransfusionComplicationsIsoimmunizationNeonatesNeonatologistsPerinatologists
1989
Pulsed Doppler flow-velocity waveforms in the prediction of fetal hematocrit of the severely isoimmunized pregnancy
Copel J, Grannum P, Green J, Belanger K, Hobbins J. Pulsed Doppler flow-velocity waveforms in the prediction of fetal hematocrit of the severely isoimmunized pregnancy. American Journal Of Obstetrics And Gynecology 1989, 161: 341-344. PMID: 2504040, DOI: 10.1016/0002-9378(89)90516-4.Peer-Reviewed Original ResearchFetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion
Copel J, Grannum P, Green J, Belanger K, Hanna N, Jaffe C, Hobbins J, Kleinman C. Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion. American Journal Of Obstetrics And Gynecology 1989, 161: 361-365. PMID: 2504042, DOI: 10.1016/0002-9378(89)90520-6.Peer-Reviewed Original ResearchConceptsCardiac outputAnemic fetusesIsoimmunized pregnanciesCombined ventricular outputDoppler echocardiographic studyFetal cardiac outputHigh output stateHigh cardiac outputIntravascular intrauterine transfusionSevere isoimmunizationCardiac indexIntrauterine transfusionIntravascular transfusionWeeks' gestationVentricular outputDoppler assessmentAge-specific normsControl fetusesHydrops fetalisControl groupMechanisms of developmentFetusesUnaffected fetusesTransfusionPregnancy
1985
Intrauterine Fetal Demise and Hemostatic Failure: The Fetal Death Syndrome.
Romero R, Copel J, Hobbins J. Intrauterine Fetal Demise and Hemostatic Failure: The Fetal Death Syndrome. Clinical Obstetrics & Gynecology 1985, 28: 24. PMID: 3987131, DOI: 10.1097/00003081-198528010-00004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements