2020
Chapter 12 Prenatal testing
Copel J, Kohari K, Merriam A. Chapter 12 Prenatal testing. 2020, 201-221. DOI: 10.1016/b978-0-12-816561-4.00012-0.ChaptersPrenatal testingMaternal-fetal medicineSecond-trimester screeningFirst-trimester screeningTime of deliveryWhole-exome sequencingChorionic villus samplingCurrent pregnancyCell-free fetal DNA screeningCertain patientsMaternal ageReproductive endocrinologyGenetic testingVillus samplingDNA screeningPatientsObstetricsSitu hybridizationScreeningTest optionsMedical GeneticsRiskGeneticsOptionsPregnancy
2019
Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions
Tuzovic L, Copel JA, Stitelman DH, Levit O, Bahtiyar MO. Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions. Journal Of Ultrasound In Medicine 2019, 38: 2361-2372. PMID: 30653685, DOI: 10.1002/jum.14931.Peer-Reviewed Original ResearchConceptsAbnormal cardiac axisNegative predictive valueFetal cardiac axisNeonatal respiratory morbidityRespiratory morbidityCongenital lung lesionsCardiac positionPositive predictive valuePredictive valueCardiac axisLung lesionsHigh negative predictive valueSevere respiratory morbidityRetrospective cohort studyRight-sided lesionsNormal cardiac axisCohort studyWeeks' gestationMorbidityCP assessmentWeeksDiagnostic performanceLesionsPatientsGestation
2012
Evaluating the cost‐effectiveness of prenatal surgery for myelomeningocele: a decision analysis
Werner E, Han C, Burd I, Lipkind H, Copel J, Bahtiyar M, Thung S. Evaluating the cost‐effectiveness of prenatal surgery for myelomeningocele: a decision analysis. Ultrasound In Obstetrics And Gynecology 2012, 40: 158-164. PMID: 22511529, DOI: 10.1002/uog.11176.Peer-Reviewed Original ResearchConceptsPrenatal myelomeningocele repairQuality-adjusted life yearsMyelomeningocele repairPostnatal repairMyelomeningocele patientsPrenatal surgeryAdditional casesLong-term medical careFuture pregnancy complicationsIncremental cost-effectiveness ratioPostnatal myelomeningocele repairCost-effectiveness ratioDecision analysis modelingUterine ruptureNeurologic deficitsPregnancy complicationsSingleton gestationsSurgery resultsLife yearsMedical carePatientsCost-effective strategyNormal karyotypeNeonatesSurgery
2003
Delivery at 34 weeks is more costly than at 35 weeks in pregnancies with premature rupture of membranes
Magriples U, Crichton R, Ehrenkranz R, Copel J. Delivery at 34 weeks is more costly than at 35 weeks in pregnancies with premature rupture of membranes. The Journal Of Maternal-Fetal & Neonatal Medicine 2003, 14: 22-25. PMID: 14563087, DOI: 10.1080/jmf.14.1.22.25.Peer-Reviewed Original ResearchConceptsPremature ruptureIntensive care unit stayPreterm premature ruptureMother-infant pairsUnit stayMaternal demographicsNeonatal morbidityPreterm PROMSingleton gestationsNeonatal interventionsNeonatal lengthRetrospective studyProspective dataRelative riskDelay of deliveryWeeksDirect costsSignificant differencesPatientsSignificant increaseStayInfantsDeliveryCost of deliveryRupture
1999
Thrombomodulin: A New Marker for Placental Abruption
Magriples U, Chan D, Bruzek D, Copel J, Hsu C. Thrombomodulin: A New Marker for Placental Abruption. Thrombosis And Haemostasis 1999, 81: 32-34. PMID: 9974370, DOI: 10.1055/s-0037-1614413.Peer-Reviewed Original ResearchConceptsPlacental abruptionAcute placental abruptionAbnormal coagulation profileProspective cohort studyEndothelial cell damageCohort studyCoagulation profilePathologic evidencePregnant womenKleihauer-BetkeAbruptionGroup 2Group 1Placental syncytiotrophoblastClinical diagnosisThrombomodulinCell damageSpecific markersNew markersPatientsMarkersDeliverySyncytiotrophoblastDiagnosisWomen
1998
Can Risk Factor Screening Predict Hepatitis C Antibody Reactivity?
Magriples U, Bernstein P, Snyder E, Copel J. Can Risk Factor Screening Predict Hepatitis C Antibody Reactivity? American Journal Of Perinatology 1998, 15: 395-398. PMID: 9722062, DOI: 10.1055/s-2007-993964.Peer-Reviewed Original ResearchConceptsHepatitis C virusPercent of womenRisk factorsEnzyme-linked immunoadsorbent assaySecond-generation testingHistory of hepatitisIntravenous drug useNegative predictive valueHCV exposureRF screeningConsecutive patientsProspective studyC virusLower riskAntibody reactivityPredictive valueDrug useImmunoadsorbent assayWomenPatientsScreeningAssaysPercentHepatitisPrevalence
1997
Is Maternal Thyrotropin Releasing Hormone Administration Safe in the Pregnant Woman with Preeclampsia?
Tan A, Hsu C, Marder S, Copel J. Is Maternal Thyrotropin Releasing Hormone Administration Safe in the Pregnant Woman with Preeclampsia? American Journal Of Perinatology 1997, 14: 5-6. PMID: 9259888, DOI: 10.1055/s-2007-994087.Peer-Reviewed Original Research
1994
Management outcome and follow-up of fetal tachycardia
van Engelen A, Weijtens O, Brenner J, Kleinman C, Copel J, Stoutenbeek P, Meijboom E. Management outcome and follow-up of fetal tachycardia. Journal Of The American College Of Cardiology 1994, 24: 1371-1375. PMID: 7930263, DOI: 10.1016/0735-1097(94)90122-8.Peer-Reviewed Original ResearchConceptsFetal tachycardiaMajority of patientsPharmacologic therapyFetal hydropsAtrial flutterSupraventricular tachycardiaVentricular tachycardiaPresence of hydropsSeries of patientsLife-threatening conditionSerious adverse effectsMonths of ageMaternal therapyProlonged therapyPostpartum managementRhythm controlAntiarrhythmic agentsMedian numberDrug treatmentTachycardiaM-modePatientsOptimal managementTherapyEmergency delivery
1993
Ultrasound screening for fetal structural anomalies
Gomez K, Copel J. Ultrasound screening for fetal structural anomalies. Current Opinion In Obstetrics & Gynecology 1993, 5: 204-210. PMID: 8490090, DOI: 10.1097/00001703-199304000-00006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFetal structural anomaliesStructural anomaliesRoutine ultrasound screeningFour-chamber viewNeural tube defectsRoutine ultrasoundUltrasound screeningHigh riskUltrasound prenatal diagnosisTube defectsUltrasoundPregnancyPrenatal diagnosisDiagnostic ultrasoundControversial topicPatientsObstetricsFetusesAmniocentesisDiagnosis
1992
Outcome of prenatally detected cardiac malformations
Smythe J, Copel J, Kleinman C. Outcome of prenatally detected cardiac malformations. The American Journal Of Cardiology 1992, 69: 1471-1474. PMID: 1590238, DOI: 10.1016/0002-9149(92)90903-c.Peer-Reviewed Original ResearchConceptsCardiac failureExtracardiac malformationsMajor extracardiac malformationsCongenital heart diseaseCardiac lesionsOptimal counselingNonimmune hydropsElective terminationExtracardiac defectsFetal echocardiographyHeart diseaseCardiac malformationsCardiac defectsChromosomal abnormalitiesMalformationsPrenatal detectionPregnancyPatientsOutcomesEchocardiographyHydropsPrognosisFailureLesionsAbnormalities
1991
Fetal echocardiography in multiple gestations
Copel J, Inati M, Green J, Hobbins J, Keinman C. Fetal echocardiography in multiple gestations. Ultrasound In Obstetrics And Gynecology 1991, 1: 111-114. PMID: 12797084, DOI: 10.1046/j.1469-0705.1991.01020111.x.Peer-Reviewed Original ResearchMultiple gestationsHeart diseaseSets of twinsFetal echocardiographyFetal cardiac defectsMaternal digitalizationWeeks' gestationCongestive failureExtracardiac malformationsCardiac anomaliesFetal echocardiogramLocation of deliveryAnomalous fetusesPatient managementCardiac defectsSets of tripletsGestationKaryotypic abnormalitiesFetusesDiseaseEchocardiographyEchocardiogramPatientsPregnancyAbnormalities
1990
Invasive Fetal Assessment in the Antepartum Period
Copel J, Gullen M, Grannum P, Hohbins J. Invasive Fetal Assessment in the Antepartum Period. Obstetrics And Gynecology Clinics Of North America 1990, 17: 201-221. PMID: 2192320, DOI: 10.1016/s0889-8545(21)00473-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsInvasive Fetal Assessment by Fetal Blood Sampling
Copel J, Grannum P. Invasive Fetal Assessment by Fetal Blood Sampling. 1990, 31-43. DOI: 10.1007/978-1-4612-3380-0_3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFetal blood samplingFetal circulationBlood samplingMaternal-fetal medicineReal-time ultrasoundPregnancy lossFetal assessmentPhysical examMaternal bloodFetal bloodPerinatal medicineFetal patientsPatientsHigh rateBloodLaboratory testsMedicineInternistsFetusesPlacentocentesisDiagnosisFetoscopyCirculation
1988
Malignant mixed müllerian tumor of the uterus arising in association with a viable gestation.
Scioscia A, Merino M, Haas M, Copel J, Schwartz P. Malignant mixed müllerian tumor of the uterus arising in association with a viable gestation. Obstetrics And Gynecology 1988, 71: 1047-50. PMID: 2836770.Peer-Reviewed Case Reports and Technical NotesConceptsMalignant mixed müllerian tumorMixed müllerian tumorMüllerian tumorInitial surgical therapyAggressive radiationPostmenopausal womenCesarean sectionSurgical therapyUneventful coursePremature infantsViable gestationPrenatal courseRare neoplasmTumorsUterusDiagnosisWomenChemotherapyPatientsGestationNeoplasmsInfantsTherapyWeeksCourse
1987
Combined echocardiographic and Doppler assessment of fetal congenital atrioventricular block
KLEINMAN C, COPEL J, HOBBINS J. Combined echocardiographic and Doppler assessment of fetal congenital atrioventricular block. BJOG An International Journal Of Obstetrics & Gynaecology 1987, 94: 967-974. PMID: 3689729, DOI: 10.1111/j.1471-0528.1987.tb02271.x.Peer-Reviewed Original ResearchConceptsHeart blockFetal echocardiographyThird-degree heart blockElective caesarean deliveryFetal heart rate monitoringDegree heart blockCongenital atrioventricular blockAtrial activityCaesarean deliveryCaesarean sectionCephalopelvic disproportionFetal bradycardiaAtrioventricular blockDoppler assessmentLate decelerationsAtrial rateHeart rate monitoringVagal toneHeart rate monitorEchocardiographyVariable degreesRate monitoringRate monitorBradycardiaPatients
1986
The value of serial human chorionic gonadotropin testing as a diagnostic tool in ectopic pregnancy
Romero R, Kadar N, Copel J, Jeanty P, DeCherney A, Hobbins J. The value of serial human chorionic gonadotropin testing as a diagnostic tool in ectopic pregnancy. American Journal Of Obstetrics And Gynecology 1986, 155: 392-394. PMID: 3740163, DOI: 10.1016/0002-9378(86)90838-0.Peer-Reviewed Original ResearchConceptsEctopic pregnancySerial human chorionic gonadotropin determinationsHuman chorionic gonadotropin testingHuman chorionic gonadotropin titersHuman chorionic gonadotropin determinationsSlope of changeIntrauterine pregnancyMIU/Serial titersGonadotropin determinationsCutoff valuePregnancyPatientsTitersDiagnostic toolTime curvePositive rateAbnormal slopeFalse positive ratePercutaneous umbilical blood sampling in the management of kell isoimmunization
Copel J, Scioscia A, Grannum P, Romero R, Reece A, Hobbins J. Percutaneous umbilical blood sampling in the management of kell isoimmunization. Obstetrics And Gynecology 1986, 67: 288-290. PMID: 3945439, DOI: 10.1097/00006250-198602000-00025.Peer-Reviewed Original ResearchConceptsPercutaneous umbilical bloodRhesus immune globulinSevere fetal diseaseHigh-resolution ultrasoundKell isoimmunizationImmune globulinUmbilical bloodRh sensitizationUmbilical cordFetal bloodFetal diseaseKell antigensAntigen systemBloodIsoimmunizationPatientsCordAntigenIncidenceDiseaseGlobulinSensitization
1985
Hermansky-Pudlak syndrome in pregnancy: Two case studies
Reiss R, Copel J, Roberts N, Hobbins J. Hermansky-Pudlak syndrome in pregnancy: Two case studies. American Journal Of Obstetrics And Gynecology 1985, 153: 564-565. PMID: 4061519, DOI: 10.1016/0002-9378(85)90475-2.Peer-Reviewed Case Reports and Technical NotesThe effect of different human chorionic gonadotropin assay sensitivity on screening for ectopic pregnancy
Romero R, Kadar N, Copel J, Jeanty P, DeCherney A, Hobbins J. The effect of different human chorionic gonadotropin assay sensitivity on screening for ectopic pregnancy. American Journal Of Obstetrics And Gynecology 1985, 153: 72-74. PMID: 4037000, DOI: 10.1016/0002-9378(85)90593-9.Peer-Reviewed Original ResearchDiagnosis of ectopic pregnancy: value of the discriminatory human chorionic gonadotropin zone.
Romero R, Kadar N, Jeanty P, Copel J, Chervenak F, DeCherney A, Hobbins J. Diagnosis of ectopic pregnancy: value of the discriminatory human chorionic gonadotropin zone. Obstetrics And Gynecology 1985, 66: 357-60. PMID: 3895079.Peer-Reviewed Original ResearchConceptsIntrauterine gestational sacEctopic pregnancyHuman chorionic gonadotropinGestational sacPredictive valueSerum hCG determinationsPercent of patientsPelvic ultrasound examinationMIU/mLNegative predictive valuePositive predictive valueHCG levelsIntrauterine gestationSerum levelsProspective studyMIU/Spontaneous abortionUltrasound examinationHCG concentrationsChorionic gonadotropinHCG determinationsPregnancyPatientsSacGestation