2022
Impact of prenatally diagnosed congenital heart defects on outcomes and management
Wong J, Kohari K, Bahtiyar MO, Copel J. Impact of prenatally diagnosed congenital heart defects on outcomes and management. Journal Of Clinical Ultrasound 2022, 50: 646-654. PMID: 35543387, DOI: 10.1002/jcu.23219.Peer-Reviewed Original ResearchConceptsCongenital heart defectsComplex congenital heart defectEarly fetal echocardiographyImproved survival ratesPrenatal detection rateGood psychosocial supportFetal echocardiogramFetal echocardiographyPatient educationCardiology specialistsHigh riskHeart defectsSurvival rateCongenital heartPsychosocial supportEarly detectionPrenatal identificationPrenatal detectionDelivery planningDetection rateUltrasound technologyImportant contributorEchocardiogramEchocardiographyNeonates
2002
Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect
Bahado-Singh RO, Rowther M, Bailey J, Copel J, Mendilcioglu I, Choi S, Oz U. Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect. American Journal Of Obstetrics And Gynecology 2002, 187: 1250-1253. PMID: 12439514, DOI: 10.1067/mob.2002.128025.Peer-Reviewed Original ResearchConceptsNuchal thickness measurementPrediction of CHDNuchal thicknessRisk factorsHeart defectsStepwise logistic regression analysisBackground population riskIndividual patient's riskEpidemiologic risk factorsSignificant risk factorsMultiple risk factorsPatient-specific riskSignificant predictorsLogistic regression analysisCongenital heart defectsOnly significant predictorMajor CHDPostnatal evaluationPatient riskMidtrimester fetusesNormal fetusesCongenital heartCHDLogistic regression
1991
Hypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management
Blake D, Copel J, Kleinman C. Hypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management. American Journal Of Obstetrics And Gynecology 1991, 165: 529-534. PMID: 1892177, DOI: 10.1016/0002-9378(91)90279-z.Peer-Reviewed Original ResearchConceptsClinical profileExtracardiac malformationsLethal congenital heart defectNeonatal intensive care settingHypoplastic left heart syndromePrenatal diagnosisIntensive care settingCongenital heart defectsPostnatal interventionsDepth counselingHeart syndromeFetal echocardiographyCare settingsNeonatal assessmentUtero diagnosisHeart defectsElective abortionInformed consentPregnancyDiagnosisAssociated geneticMalformationsComplete evaluationInterventionCounselingPerinatal outcome of fetal complete atrioventricular block: A multicenter experience
Schmidt K, Ulmer H, Silverman N, Kleinman C, Copel J. Perinatal outcome of fetal complete atrioventricular block: A multicenter experience. Journal Of The American College Of Cardiology 1991, 17: 1360-1366. PMID: 2016455, DOI: 10.1016/s0735-1097(10)80148-2.Peer-Reviewed Original ResearchConceptsComplete atrioventricular blockBeats/minStructural heart defectsAtrial isomerismAtrioventricular blockVentricular rateAV blockAtrial rateHeart defectsFetal complete atrioventricular blockDiscordant AV connectionsLeft atrial isomerismConnective tissue diseaseNormal cardiac anatomySecond-degree blockComplete AV blockComplex structural heart defectsSlow atrial rateAntinuclear antibodiesPerinatal outcomesAV connectionsMulticenter experienceClinical courseNeonatal deathTissue disease