2020
Fixed Compared With Autoregulation-Oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke
Petersen NH, Silverman A, Strander SM, Kodali S, Wang A, Sansing LH, Schindler JL, Falcone GJ, Gilmore EJ, Jasne AS, Cord B, Hebert RM, Johnson M, Matouk CC, Sheth KN. Fixed Compared With Autoregulation-Oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke. Stroke 2020, 51: 914-921. PMID: 32078493, PMCID: PMC7050651, DOI: 10.1161/strokeaha.119.026596.Peer-Reviewed Original ResearchConceptsSystolic BP thresholdMean arterial pressureArterial pressureEndovascular thrombectomyIschemic strokeSystolic BPFunctional outcomePercent timeFurther brain injuryModified Rankin ScaleBlood pressure changesPoor functional outcomeBP thresholdAutoregulatory indexHemorrhagic transformationMechanical thrombectomyRankin ScaleBlood pressureBP targetsHemodynamic managementAcute phaseBP managementStroke patientsCerebral autoregulationWorse outcomes
2008
Impaired cerebral autoregulation in obstructive sleep apnea
Urbano F, Roux F, Schindler J, Mohsenin V. Impaired cerebral autoregulation in obstructive sleep apnea. Journal Of Applied Physiology 2008, 105: 1852-1857. PMID: 18927265, DOI: 10.1152/japplphysiol.90900.2008.Peer-Reviewed Original ResearchConceptsCerebral artery blood flow velocityObstructive sleep apneaBlood pressureCerebral autoregulationOSA patientsCerebral ischemiaSleep apneaOSA groupMean CBFVActive coronary artery diseaseMean apnea-hypopnea indexCerebral vascular conductanceImpaired cerebral autoregulationMetabolic risk factorsApnea-hypopnea indexArterial blood pressureRisk of strokeCoronary artery diseaseEvents/hEvidence of hypercoagulabilityObstructive apnea eventsCerebral blood flowTranscranial Doppler ultrasoundBlood flow velocityCerebrovascular conductance