2003
Cl− flux through a non‐selective, stretch‐sensitive conductance influences the outer hair cell motor of the guinea‐pig
Rybalchenko V, Santos‐Sacchi J. Cl− flux through a non‐selective, stretch‐sensitive conductance influences the outer hair cell motor of the guinea‐pig. The Journal Of Physiology 2003, 547: 873-891. PMID: 12562920, PMCID: PMC2342734, DOI: 10.1111/j.1469-7793.2003.00873.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarbenoxoloneCell MembraneChloride ChannelsChloridesCyclooxygenase InhibitorsElectric CapacitanceElectric ConductivityGadoliniumGuinea PigsHair Cells, Auditory, OuterIon Channel GatingMechanotransduction, CellularMembrane PotentialsMercuric ChlorideMicrodialysisNiflumic AcidOctanolsProteinsSulfonic AcidsConceptsOuter hair cell motorLateral membranesVoltage-dependent conformational changesLateral plasma membranePlasma membraneMotor proteinsCell motorProtein transitionsConformational changesRecent identificationPrestinSomatic motilityAllosteric modulationCL sensitivityAnion fluxHair cellsCochlear amplificationAcoustic ratesOuter hair cellsAlternative mechanismComplicated roleMembranePronounced shiftCellsAmplification
1991
Isolated supporting cells from the organ of Corti: Some whole cell electrical characteristics and estimates of gap junctional conductance
Santos-Sacchi J. Isolated supporting cells from the organ of Corti: Some whole cell electrical characteristics and estimates of gap junctional conductance. Hearing Research 1991, 52: 89-98. PMID: 2061216, DOI: 10.1016/0378-5955(91)90190-k.Peer-Reviewed Original ResearchConceptsInput resistanceWhole-cell voltage clamp studiesAverage input resistanceHensen's cellsOrgan of CortiVoltage-clamp studiesGuinea pig organJunctional resistanceClamp studiesCell levelPig organsSingle-cell levelGap junctional conductanceG omegaElectrical activityExternal TEACell couplingCortiJunctional conductanceCellsOrgansSensitive indicatorSmall groupCell values