2011
Calcium-Dependent Synaptic Vesicle Trafficking Underlies Indefatigable Release at the Hair Cell Afferent Fiber Synapse
Schnee ME, Santos-Sacchi J, Castellano-Muñoz M, Kong JH, Ricci AJ. Calcium-Dependent Synaptic Vesicle Trafficking Underlies Indefatigable Release at the Hair Cell Afferent Fiber Synapse. Neuron 2011, 70: 326-338. PMID: 21521617, PMCID: PMC3254016, DOI: 10.1016/j.neuron.2011.01.031.Peer-Reviewed Original Research
2005
Glibenclamide Stimulates Fluid Secretion in Rodent Cholangiocytes Through a Cystic Fibrosis Transmembrane Conductance Regulator-Independent Mechanism
Spirlì C, Fiorotto R, Song L, Santos-Sacchi J, Okolicsanyi L, Masier S, Rocchi L, Vairetti MP, de Bernard M, Melero S, Pozzan T, Strazzabosco M. Glibenclamide Stimulates Fluid Secretion in Rodent Cholangiocytes Through a Cystic Fibrosis Transmembrane Conductance Regulator-Independent Mechanism. Gastroenterology 2005, 129: 220-233. PMID: 16012949, DOI: 10.1053/j.gastro.2005.03.048.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsATP-Binding Cassette TransportersBile DuctsBody FluidsCalciumCell LineCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorElectric CapacitanceElectric ConductivityGlyburideHypoglycemic AgentsLiverMiceMice, Inbred CFTRPatch-Clamp TechniquesPotassium ChannelsPotassium Channels, Inwardly RectifyingRatsReceptors, DrugSulfonylurea ReceptorsConceptsCystic fibrosisBiliary ductsCholangiocyte secretionFluid secretionAbility of glibenclamideCystic fibrosis transmembrane conductance regulatorIntracellular Ca 2Liver impairmentSevere complicationsLiver diseaseCholestatic diseaseRodent cholangiocytesGlibenclamideInhibitors of exocytosisAbstractTextFibrosisSecretionSecretory mechanismDiseaseMiceCholangiocytesRat cholangiocytesCFTR inhibitor
1998
Effect of Membrane Tension on Gap Junctional Conductance of Supporting Cells in Corti's Organ
Zhao H, Santos-Sacchi J. Effect of Membrane Tension on Gap Junctional Conductance of Supporting Cells in Corti's Organ. The Journal Of General Physiology 1998, 112: 447-455. PMID: 9758863, PMCID: PMC2229429, DOI: 10.1085/jgp.112.4.447.Peer-Reviewed Original ResearchConceptsTurgor pressureInner ear gap junctionsMembrane tensionPositive turgor pressureProtein kinase inhibitorsGap junctionsOsmotic pressure regulationPipette pressureSupporting cellsInner earMicroM HCochlear homeostasisGap junctional conductanceKinase inhibitorsMechanical forcesCell sizeJunctional conductance
1994
Cell coupling in the supporting cells of Corti's organ: Sensitivity to intracellular H+ and Ca+2
Sato Y, Santos-Sacchi J. Cell coupling in the supporting cells of Corti's organ: Sensitivity to intracellular H+ and Ca+2. Hearing Research 1994, 80: 21-24. PMID: 7852199, DOI: 10.1016/0378-5955(94)90004-3.Peer-Reviewed Original Research
1986
The temperature dependence of electrical coupling in the organ of Corti
Santos-Sacchi J. The temperature dependence of electrical coupling in the organ of Corti. Hearing Research 1986, 21: 205-211. PMID: 2424883, DOI: 10.1016/0378-5955(86)90219-4.Peer-Reviewed Original Research
1980
Potentiation of the cGMP‐induced Guinea pig acrosome reaction by zinc
Santos‐Sacchi J, Gordon M, Williams W. Potentiation of the cGMP‐induced Guinea pig acrosome reaction by zinc. Journal Of Experimental Zoology 1980, 213: 289-291. PMID: 6257821, DOI: 10.1002/jez.1402130217.Peer-Reviewed Original Research