2000
Nitric oxide uncouples gap junctions of supporting Deiters cells from Corti's organ
Blasits S, Maune S, Santos-Sacchi J. Nitric oxide uncouples gap junctions of supporting Deiters cells from Corti's organ. Pflügers Archiv - European Journal Of Physiology 2000, 440: 710-712. PMID: 11007311, DOI: 10.1007/s004240000355.Peer-Reviewed Original ResearchConceptsDeiters' cellsCorti's organNO/cGMP pathwayNitric oxide donor sodium nitroprussideWhole-cell voltage-clamp conditionsNO synthase inhibitorUncouple gap junctionsNormal sensory functionDonor sodium nitroprussideGap junctionsVoltage-clamp conditionsOtotoxic mechanismsMinutes of applicationCGMP pathwayGap junctional communicationSodium nitroprussideSynthase inhibitorCochlear homeostasisSensory functionElectrical uncouplingNitric oxideCGMP analogJunctional communicationOrgansCellsVoltage Gating of Gap Junctions in Cochlear Supporting Cells: Evidence for Nonhomotypic Channels
Zhao H, Santos-Sacchi J. Voltage Gating of Gap Junctions in Cochlear Supporting Cells: Evidence for Nonhomotypic Channels. The Journal Of Membrane Biology 2000, 175: 17-24. PMID: 10811964, DOI: 10.1007/s002320001051.Peer-Reviewed Original Research
1998
Effect of Membrane Tension on Gap Junctional Conductance of Supporting Cells in Corti's Organ
Zhao H, Santos-Sacchi J. Effect of Membrane Tension on Gap Junctional Conductance of Supporting Cells in Corti's Organ. The Journal Of General Physiology 1998, 112: 447-455. PMID: 9758863, PMCID: PMC2229429, DOI: 10.1085/jgp.112.4.447.Peer-Reviewed Original ResearchConceptsTurgor pressureInner ear gap junctionsMembrane tensionPositive turgor pressureProtein kinase inhibitorsGap junctionsOsmotic pressure regulationPipette pressureSupporting cellsInner earMicroM HCochlear homeostasisGap junctional conductanceKinase inhibitorsMechanical forcesCell sizeJunctional conductance
1994
Cell coupling in the supporting cells of Corti's organ: Sensitivity to intracellular H+ and Ca+2
Sato Y, Santos-Sacchi J. Cell coupling in the supporting cells of Corti's organ: Sensitivity to intracellular H+ and Ca+2. Hearing Research 1994, 80: 21-24. PMID: 7852199, DOI: 10.1016/0378-5955(94)90004-3.Peer-Reviewed Original Research
1985
The effects of cytoplasmic acidification upon electrical coupling in the organ of Corti
Santos-Sacchi J. The effects of cytoplasmic acidification upon electrical coupling in the organ of Corti. Hearing Research 1985, 19: 207-215. PMID: 3934121, DOI: 10.1016/0378-5955(85)90140-6.Peer-Reviewed Original Research
1983
Intercellular communication in the supporting cells of the organ of Corti
Santos-Sacchi J, Dallos P. Intercellular communication in the supporting cells of the organ of Corti. Hearing Research 1983, 9: 317-326. PMID: 6841286, DOI: 10.1016/0378-5955(83)90034-5.Peer-Reviewed Original Research