2023
Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials
Wallach J, Deng Y, Polley E, Dhruva S, Herrin J, Quinto K, Gandotra C, Crown W, Noseworthy P, Yao X, Jeffery M, Lyon T, Ross J, McCoy R. Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials. Clinical Trials 2023, 20: 689-698. PMID: 37589143, PMCID: PMC10843567, DOI: 10.1177/17407745231193137.Peer-Reviewed Original ResearchConceptsBaseline participant characteristicsParticipant characteristicsPrimary endpointSecondary endpointsTrial publicationsMajor adverse cardiovascular eventsPropensity score-matched participantsFirst major adverse cardiovascular eventAdverse cardiovascular eventsBaseline patient characteristicsNonfatal myocardial infarctionOptumLabs Data WarehouseElectronic health record dataRepresentative patient populationHealth record dataCardiovascular eventsClinical characteristicsPatient characteristicsPatient populationMyocardial infarctionExclusion criteriaDrug effectivenessTrialsRecord dataEndpoint
2021
The Association Between History of Depression and Access to Care Among Medicare Beneficiaries During the COVID-19 Pandemic
Balasuriya L, Quinton JK, Canavan ME, Holland ML, Edelman EJ, Druss BG, Ross JS. The Association Between History of Depression and Access to Care Among Medicare Beneficiaries During the COVID-19 Pandemic. Journal Of General Internal Medicine 2021, 36: 3778-3785. PMID: 34405350, PMCID: PMC8370448, DOI: 10.1007/s11606-021-06990-4.Peer-Reviewed Original ResearchConceptsSelf-reported historyHistory of depressionMental health outcomesMedicare beneficiariesHealth outcomesCOVID-19Adverse health outcomesPARTICIPANTSCross-sectional studyMental health effectsUnmet social needsClinical characteristicsHigh riskKey ResultsParticipantsPublic Use FileMedical careGreater riskMental healthHealth effectsCareDepressionUse FileCOVID-19 pandemicOutcomesGreater inabilityMedicare
2014
Payments for Acute Myocardial Infarction Episodes-of-Care Initiated at Hospitals With and Without Interventional Capabilities
Ben-Josef G, Ott LS, Spivack SB, Wang C, Ross JS, Shah SJ, Curtis JP, Kim N, Krumholz HM, Bernheim SM. Payments for Acute Myocardial Infarction Episodes-of-Care Initiated at Hospitals With and Without Interventional Capabilities. Circulation Cardiovascular Quality And Outcomes 2014, 7: 882-888. PMID: 25387777, DOI: 10.1161/circoutcomes.114.000927.Peer-Reviewed Original ResearchConceptsNon-PCI hospitalsCoronary artery bypass graft ratesPCI hospitalsAcute myocardial infarctionMyocardial infarctionPercutaneous coronary intervention capabilityAcute myocardial infarction admissionsLower revascularization ratesPrincipal discharge diagnosisTreatment of patientsMyocardial infarction admissionsHigh rateMyocardial infarction episodeGraft ratePCI capabilityPCI useIndex admissionRevascularization ratesClinical characteristicsPatient demographicsDays postadmissionDischarge diagnosisMedicare patientsCare proceduresMedicare feeHospital variation in risk-standardized hospital admission rates from US EDs among adults
Capp R, Ross JS, Fox JP, Wang Y, Desai MM, Venkatesh AK, Krumholz HM. Hospital variation in risk-standardized hospital admission rates from US EDs among adults. The American Journal Of Emergency Medicine 2014, 32: 837-843. PMID: 24881514, DOI: 10.1016/j.ajem.2014.03.033.Peer-Reviewed Original ResearchConceptsHospital admission ratesEmergency departmentAdmission ratesClinical characteristicsED visitsHospital factorsClinical factorsAdult ED visitsUS emergency departmentsHospital teaching statusCross-sectional analysisPatient characteristicsHospital admissionHospital variationPatientsTeaching statusHospitalED dataVisitsRepresentative sampleAdultsRural locationsAdmissionFactorsNational variations
2009
Self-Reported and Actual Beta-Blocker Prescribing for Heart Failure Patients: Physician Predictors
Sinha S, Schwartz MD, Qin A, Ross JS. Self-Reported and Actual Beta-Blocker Prescribing for Heart Failure Patients: Physician Predictors. PLOS ONE 2009, 4: e8522. PMID: 20046824, PMCID: PMC2796176, DOI: 10.1371/journal.pone.0008522.Peer-Reviewed Original ResearchConceptsBeta-blocker prescribingSelf-reported prescribingHF patientsSystolic heart failureHeart failurePhysician characteristicsActual prescribingPrimary care physician characteristicsVeterans Affairs Medical CenterRetrospective chart reviewHeart failure patientsPrimary care providersCross-sectional surveySelf-reported ratesHF carePhysician predictorsChart reviewClinical characteristicsFailure patientsPrescription ratesPrimary carePrescribing dataInpatient wardsPractice patternsMedical CenterCognitive Decline among Patients with Chronic Obstructive Pulmonary Disease
Hung WW, Wisnivesky JP, Siu AL, Ross JS. Cognitive Decline among Patients with Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2009, 180: 134-137. PMID: 19423714, DOI: 10.1164/rccm.200902-0276oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseSevere chronic obstructive pulmonary diseaseObstructive pulmonary diseaseCognitive declinePulmonary diseaseEffect of COPDHistory of COPDPopulation-based longitudinal cohortOlder adultsSmall case seriesMultivariable mixed linear modelCognitive performanceLower cognitive performanceClinical characteristicsMultivariable adjustmentPrimary outcomeCase seriesClinical historyLongitudinal cohortActivity limitationsCognitive testingAdultsCognition scoresMean scoreStandardized measurements
2007
Certificate of Need Regulation and Cardiac Catheterization Appropriateness After Acute Myocardial Infarction
Ross JS, Ho V, Wang Y, Cha SS, Epstein AJ, Masoudi FA, Nallamothu BK, Krumholz HM. Certificate of Need Regulation and Cardiac Catheterization Appropriateness After Acute Myocardial Infarction. Circulation 2007, 115: 1012-1019. PMID: 17283258, DOI: 10.1161/circulationaha.106.658377.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionCardiac catheterizationHospital coronary artery bypass graft surgeryCoronary artery bypass graft surgeryArtery bypass graft surgeryLower ratesUS acute care hospitalsCardiac catheterization capabilitiesChart-abstracted dataBypass graft surgeryDay of admissionAcute care hospitalsComplex medical careQuality of careGraft surgeryCatheterization ratesClinical characteristicsCON regulationsHospital characteristicsMedicare patientsRetrospective analysisCatheterizationHealthcare costsFull cohort