2000
Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle
Haas T, Milkiewicz M, Davis S, Zhou A, Egginton S, Brown M, Madri J, Hudlicka O. Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle. AJP Heart And Circulatory Physiology 2000, 279: h1540-h1547. PMID: 11009439, DOI: 10.1152/ajpheart.2000.279.4.h1540.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCapillariesCell DivisionDipeptidesElectric StimulationImmunohistochemistryMatrix Metalloproteinase 2Matrix Metalloproteinase InhibitorsMatrix Metalloproteinases, Membrane-AssociatedMetalloendopeptidasesMicroscopy, ElectronMotor ActivityMuscle, SkeletalNeovascularization, PhysiologicProtease InhibitorsRatsRNA, MessengerConceptsMembrane proteinsBasement membrane proteinsEndothelial cell sprout formationRat skeletal muscleSkeletal muscleMatrix metalloproteinasesMembrane type 1Inflammation-mediated angiogenesisPhysiological angiogenesisBasement membraneCell proliferationMMP proteolysisProtein levelsProteolysisSprout formationMajor classesCritical roleProteinMatrix metalloproteinase activityMetalloproteinase activityProliferationAngiogenesisNew capillariesMembraneMMP inhibition
1995
Germinal matrix microvascular maturation correlates inversely with the risk period for neonatal intraventricular hemorrhage
Ment L, Stewart W, Ardito T, Madri J. Germinal matrix microvascular maturation correlates inversely with the risk period for neonatal intraventricular hemorrhage. Brain Research 1995, 84: 142-149. PMID: 7720213, DOI: 10.1016/0165-3806(94)00168-y.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell MembraneCerebral HemorrhageDisease Models, AnimalFemaleHumansInfant, NewbornMicrocirculationMicroscopy, ElectronRisk FactorsConceptsNeonatal intraventricular hemorrhageIntraventricular hemorrhagePostnatal dayRisk periodDay 1Blood-brain barrierNewborn beagle pupsTenth postnatal dayEndothelial cell areaBasal lamina depositionPerinatal inductionPreterm neonatesBasement membrane areaWeeks' gestationGestational agePostnatal ageGerminal matrixBeagle pupsElectron microscopic examinationLuminal areaTight junction lengthWhite matterDay 10Time pointsBeagle model
1990
Transforming growth factor beta1 modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis
Merwin J, Anderson J, Kocher O, Van Itallie C, Madri J. Transforming growth factor beta1 modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis. Journal Of Cellular Physiology 1990, 142: 117-128. PMID: 1688859, DOI: 10.1002/jcp.1041420115.Peer-Reviewed Original Research
1989
Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.
Madri J, Reidy M, Kocher O, Bell L. Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin. Laboratory Investigation 1989, 60: 755-65. PMID: 2659888.Peer-Reviewed Original ResearchAnimalsBlotting, NorthernCarotid ArteriesCatheterizationCell DivisionCell MovementCells, CulturedCollagenCulture MediaEndothelium, VascularEnzyme-Linked Immunosorbent AssayFibronectinsImmunologic TechniquesMicroscopy, ElectronMicroscopy, Electron, ScanningRatsRats, Inbred StrainsRNA, MessengerTransforming Growth Factors
1988
Extracellular matrix specificity for the differentiation of capillary endothelial cells
Carley W, Milici A, Madri J. Extracellular matrix specificity for the differentiation of capillary endothelial cells. Experimental Cell Research 1988, 178: 426-434. PMID: 3049122, DOI: 10.1016/0014-4827(88)90411-9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell LineEndothelium, VascularExtracellular MatrixFluorescent Antibody TechniqueMicroscopy, ElectronConceptsExtracellular matrixCapillary endothelial cellsEndothelial cellsSpecific extracellular matrixEndothelial cell migrationVivo phenotypeDifferentiated phenotypeCell migrationCell typesCell growthCell dedifferentiationEndothelial cell growthMatrix componentsMembrane structurePhenotypeCellsExpressionCulture methodCytoplasmProteinGrowthMadinDifferentiationDedifferentiationGreater number
1987
The microvascular extracellular matrix. Developmental changes during angiogenesis in the aortic ring-plasma clot model.
Nicosia R, Madri J. The microvascular extracellular matrix. Developmental changes during angiogenesis in the aortic ring-plasma clot model. American Journal Of Pathology 1987, 128: 78-90. PMID: 2440308, PMCID: PMC1899791.Peer-Reviewed Original Research
1986
Repopulation of a human alveolar matrix by adult rat type II pneumocytes in vitro A novel system for type II pneumocyte culture
Lwebuga-Mukasa J, Ingbar D, Madri J. Repopulation of a human alveolar matrix by adult rat type II pneumocytes in vitro A novel system for type II pneumocyte culture. Experimental Cell Research 1986, 162: 423-435. PMID: 3510880, DOI: 10.1016/0014-4827(86)90347-2.Peer-Reviewed Original ResearchBasement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro.
Ingber DE, Madri JA, Jamieson JD. Basement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro. American Journal Of Pathology 1986, 122: 129-39. PMID: 3942197, PMCID: PMC1888129.Peer-Reviewed Original ResearchConceptsDistinct membrane domainsEpithelial cell-cell interactionsCell shape changesCell-cell interactionsAcinar tumor cellsMembrane domainsTumor cellsBasement membranePolarized distributionSpatial organizersGolgi complexProtein synthesisIndividual cellsCell surfaceLipid dropletsIntracellular actinPancreatic acinar carcinomaJunctional complexesEpithelial tumor cellsCell contactCytoskeletal alterationsAmniotic basement membraneEpithelial orientationIntact basement membraneZymogen granules
1985
Endothelial Cell‐Extracellular Matrix Interactionsa
PRATT B, FORM D, MADRI J. Endothelial Cell‐Extracellular Matrix Interactionsa. Annals Of The New York Academy Of Sciences 1985, 460: 274-288. PMID: 3868952, DOI: 10.1111/j.1749-6632.1985.tb51175.x.Peer-Reviewed Original ResearchImmunolocalization of type IV collagen and laminin in nonbasement membrane structures of murine corneal stroma. A light and electron microscopic study.
Pratt B, Madri J. Immunolocalization of type IV collagen and laminin in nonbasement membrane structures of murine corneal stroma. A light and electron microscopic study. Laboratory Investigation 1985, 52: 650-6. PMID: 3892156.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCollagenCorneaCorneal StromaFluorescent Antibody TechniqueHistocytochemistryMiceMicroscopy, ElectronMyofibrilsRatsConceptsElectron microscopic immunolocalizationMicrofibril bundlesInterstitial collagen types IType IV collagenPossible functionsExtracellular matrixImmunofluorescent localizationMembrane structureIV collagenCollagen type IType IType V collagenOxytalan microfibrilsImmunolocalizationCellular sourceMicrofibrilsLamininCharacterization of the tissue form of type V collagen from chick bone.
Broek D, Madri J, Eikenberry E, Brodsky B. Characterization of the tissue form of type V collagen from chick bone. Journal Of Biological Chemistry 1985, 260: 555-562. PMID: 3965462, DOI: 10.1016/s0021-9258(18)89768-x.Peer-Reviewed Original ResearchConceptsSodium dodecyl sulfate-polyacrylamide gel electrophoresisDodecyl sulfate-polyacrylamide gel electrophoresisSulfate-polyacrylamide gel electrophoresisGlobular domainType V collagenCyanogen bromide peptide mapsTriple-helical domainGel electrophoresisIsolated alpha chainHelical domainTriple helixForm of alphaBanding patternsChick bonePeptide mapsProtein bandsBacterial collagenase digestionTerminal peptidesRotary shadowingHigh molecular weight formAlpha chainTissue formMolecular weight formsSlower mobilityHelix
1984
An acellular human amnionic membrane model for in vitro culture of type ii pneumocytes: The role of the basement membrane in cell morphology and function
Lwebuga‐Mukasa J, Thulin G, Madri J, Barrett C, Warshaw J. An acellular human amnionic membrane model for in vitro culture of type ii pneumocytes: The role of the basement membrane in cell morphology and function. Journal Of Cellular Physiology 1984, 121: 215-225. PMID: 6548224, DOI: 10.1002/jcp.1041210127.Peer-Reviewed Original ResearchStudies on the Interaction of Human Plasma-Fibronectin with Native Type I Calf Skin Collagen Molecules Using the Rotary Shadowing Technique
Lwebuga-Mukasa J, Madri J, Albert J, Furthmayr H. Studies on the Interaction of Human Plasma-Fibronectin with Native Type I Calf Skin Collagen Molecules Using the Rotary Shadowing Technique. Collagen And Related Research 1984, 4: 95-110. PMID: 6723254, DOI: 10.1016/s0174-173x(84)80018-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBinding SitesCattleCollagenFibronectinsHumansIn Vitro TechniquesMicroscopy, ElectronPolymersSkin
1983
Ultrastructural morphology and domain structure of a unique collagenous component of basement membranes.
Madri J, Foellmer H, Furthmayr H. Ultrastructural morphology and domain structure of a unique collagenous component of basement membranes. Biochemistry 1983, 22: 2797-804. PMID: 6409144, DOI: 10.1021/bi00281a005.Peer-Reviewed Original Research
1982
Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.
Rao C, Margulies I, Tralka T, Terranova V, Madri J, Liotta L. Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment. Journal Of Biological Chemistry 1982, 257: 9740-9744. PMID: 7107589, DOI: 10.1016/s0021-9258(18)34135-8.Peer-Reviewed Original ResearchConceptsElectron microscopySubunits of lamininGlobular end regionsBeta subunitLaminin short armsTumor cellsWhole laminin moleculeAlpha subunitSquamous carcinoma cellsHuman squamous carcinoma cellsMicroscopyCell attachmentLaminin moleculeAttachment propertiesCarcinoma cellsTumor cell attachmentBasement membraneLong armAlpha-thrombinRotary Shadowing of Connective Tissue Macromolecules
Furthmayr H, Madri J. Rotary Shadowing of Connective Tissue Macromolecules. Collagen And Related Research 1982, 2: 349-363. PMID: 7128049, DOI: 10.1016/s0174-173x(82)80025-3.Peer-Reviewed Original ResearchType V Collagens of the Human Placenta: Trimer α-Chain Composition, Ultrastructural Morphology and Peptide Analysis
Madri J, Foellmer H, Furthmayr H. Type V Collagens of the Human Placenta: Trimer α-Chain Composition, Ultrastructural Morphology and Peptide Analysis. Collagen And Related Research 1982, 2: 19-29. PMID: 7105646, DOI: 10.1016/s0174-173x(82)80038-1.Peer-Reviewed Original Research
1981
Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix
Engel J, Odermatt E, Engel A, Madri J, Furthmayr H, Rohde H, Timpl R. Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix. Journal Of Molecular Biology 1981, 150: 97-120. PMID: 6795355, DOI: 10.1016/0022-2836(81)90326-0.Peer-Reviewed Original Research
1980
The collagenous components of the subendothelium. Correlation of structure and function.
Madri J, Dreyer B, Pitlick F, Furthmayr H. The collagenous components of the subendothelium. Correlation of structure and function. Laboratory Investigation 1980, 43: 303-15. PMID: 7003251.Peer-Reviewed Original ResearchConceptsCell surfaceEndothelial cell surfaceEndothelial cellsSpecific immunoprecipitation techniquesBiosynthetic incorporationImmunofluorescence microscopyImmunoelectron microscopyImmunoprecipitation techniquesAB2 collagenCellsCollagenous componentsAggregation occursCorrelation of structureCollagen typesImportant roleMonolayer of endotheliumCollagenPlatelet adhesionPlatelet aggregationImportant determinantNonthrombogenic surfaceVascular wallTreesType IVAdhesionUltrastructural localization of fibronectin and laminin in the basement membranes of the murine kidney.
Madri J, Roll F, Furthmayr H, Foidart J. Ultrastructural localization of fibronectin and laminin in the basement membranes of the murine kidney. Journal Of Cell Biology 1980, 86: 682-687. PMID: 6995470, PMCID: PMC2111490, DOI: 10.1083/jcb.86.2.682.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBasement MembraneFibronectinsGlycoproteinsImmunologic TechniquesKidneyKidney GlomerulusLamininMiceMicroscopy, ElectronConceptsTubular basement membraneMesangial areaBowman's capsuleMesangial matrixBasement membraneFrozen sectionsNormal murine kidneyMurine kidneyAffinity-purified rabbit antibodiesConventional frozen sectionsGlomerular basement membraneSheep anti-rabbit IgGLaminin labellingThick frozen sectionsImmunofluorescence stainingSpecific antibodiesRabbit antibodiesLamina rara internaMesangial cell processesKidneyUltrastructural levelCapsuleAntibodiesAnti-rabbit IgGLaminin