2006
Modeling the neurovascular niche: VEGF‐ and BDNF‐mediated cross‐talk between neural stem cells and endothelial cells: An in vitro study
Li Q, Ford MC, Lavik EB, Madri JA. Modeling the neurovascular niche: VEGF‐ and BDNF‐mediated cross‐talk between neural stem cells and endothelial cells: An in vitro study. Journal Of Neuroscience Research 2006, 84: 1656-1668. PMID: 17061253, DOI: 10.1002/jnr.21087.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceAnimalsAnimals, NewbornBrainBrain-Derived Neurotrophic FactorCell CommunicationCell ProliferationCells, CulturedCoculture TechniquesEndothelial CellsEnzyme-Linked Immunosorbent AssayGreen Fluorescent ProteinsMiceMice, Inbred C57BLMice, TransgenicMicroscopy, Electron, TransmissionModels, BiologicalNerve Tissue ProteinsNeuronsNitric OxidePlatelet Endothelial Cell Adhesion Molecule-1Stem CellsVascular Endothelial Growth Factor AConceptsBrain-derived neurotrophic factorBrain-derived endothelial cellsNeural stem cellsNeurovascular nicheTube formationResident neural stem cellsEndothelial cellsCell-derived soluble factorsVascular endothelial growth factorStem cellsNitric oxide scavengerEndothelial growth factorPaucity of dataExogenous NO donorNeurotrophic factorStem cell modulationVascular tube formationCell modulationENOS activationNO donorSoluble factorsGrowth factorNeuronal differentiationReciprocal modulationInductionEffects of a novel tylophorine analog on collagen‐induced arthritis through inhibition of the innate immune response
You X, Pan M, Gao W, Shiah H, Tao J, Zhang D, Koumpouras F, Wang S, Zhao H, Madri JA, Baker D, Cheng Y, Yin Z. Effects of a novel tylophorine analog on collagen‐induced arthritis through inhibition of the innate immune response. Arthritis & Rheumatism 2006, 54: 877-886. PMID: 16508970, DOI: 10.1002/art.21640.Peer-Reviewed Original ResearchConceptsCollagen-induced arthritisBone marrow-derived dendritic cellsMarrow-derived dendritic cellsInnate immune responseDendritic cellsProinflammatory cytokinesTylophorine analogsImmune responseOnset of CIAProgression of CIACytometric bead array analysisTumor necrosis factor alphaB cell antibody responseDevelopment of arthritisNecrosis factor alphaT cell proliferationBead array analysisNovel therapeutic agentsEnzyme-linked immunosorbent assayInflammatory arthritisJoint inflammationInflammatory cytokinesAntibody responseClinical severityPathologic changes
1989
Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.
Madri J, Reidy M, Kocher O, Bell L. Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin. Laboratory Investigation 1989, 60: 755-65. PMID: 2659888.Peer-Reviewed Original ResearchAnimalsBlotting, NorthernCarotid ArteriesCatheterizationCell DivisionCell MovementCells, CulturedCollagenCulture MediaEndothelium, VascularEnzyme-Linked Immunosorbent AssayFibronectinsImmunologic TechniquesMicroscopy, ElectronMicroscopy, Electron, ScanningRatsRats, Inbred StrainsRNA, MessengerTransforming Growth Factors
1988
Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.
Madri J, Pratt B, Tucker A. Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix. Journal Of Cell Biology 1988, 106: 1375-1384. PMID: 3283153, PMCID: PMC2115017, DOI: 10.1083/jcb.106.4.1375.Peer-Reviewed Original Research
1987
An immunohistochemical and serum ELISA study of type I and III procollagen aminopropeptides in primary biliary cirrhosis.
Davis B, Madri J. An immunohistochemical and serum ELISA study of type I and III procollagen aminopropeptides in primary biliary cirrhosis. American Journal Of Pathology 1987, 128: 265-75. PMID: 3303951, PMCID: PMC1899633.Peer-Reviewed Original ResearchMeSH KeywordsAntibody SpecificityAspartate AminotransferasesBilirubinCross ReactionsEnzyme-Linked Immunosorbent AssayHistocytochemistryHumansImmunoenzyme TechniquesLiver Cirrhosis, BiliaryPeptide FragmentsProcollagenConceptsType III procollagenPrimary biliary cirrhosisDegree of fibrosisSerum levelsBiliary cirrhosisType ICorresponding liver biopsiesGroup of patientsLevel of inflammationLiver biopsyNormal limitsInflammationELISA studiesCirrhosisAminopropeptideFibrosisELISA methodologyProcollagenMature type IBiopsyPatientsLevelsImmunohistochemistryImmunoperoxidaseLiverType I and type III procollagen peptides during hepatic fibrogenesis. An immunohistochemical and ELISA serum study in the CCl4 rat model.
Davis B, Madri J. Type I and type III procollagen peptides during hepatic fibrogenesis. An immunohistochemical and ELISA serum study in the CCl4 rat model. American Journal Of Pathology 1987, 126: 137-47. PMID: 2433943, PMCID: PMC1899545.Peer-Reviewed Original ResearchConceptsDays of treatmentSGPT valuesHepatic fibrogenesisSerum assaysProcollagen peptideType IHepatic collagen depositionUseful clinical indicatorCCl4 rat modelCarbon tetrachloride modelExtracellular collagen degradationHistologic inflammationSGPT levelsClinical indicatorsHepatic fibrosisHistologic fibrosisRat modelRoutine histologicSerum studiesClinical utilityCollagen depositionLinear regression analysisNormal levelsELISA assaysImmunofluorescent staining
1984
Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4
Merrill W, Barwick K, Madri J, Strober W, Matthay R, Olchowski J, Naegel G, Reynolds H. Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 905-9. PMID: 6208835, DOI: 10.1164/arrd.1984.130.5.905.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBronchiCarcinomaEnzyme-Linked Immunosorbent AssayEpitheliumGlycoproteinsHumansKeratinsLung NeoplasmsMiddle AgedSmokingTherapeutic IrrigationConceptsFree secretory componentSymptomatic smokersCarcinoma patientsAsymptomatic smokersLavage fluidLung diseaseCancer patientsSmoking-associated lung diseasePacks/yearHigh-risk subgroupsImportant etiologic factorNumber of smokersAirway changesAirway injuryGroups of subjectsHealthy smokersSmoking historyNormal nonsmokersLavage levelsCigarette smokingSmoking populationEtiologic factorsLavage proteinImmunohistochemical evidenceLung sections
1983
Use of avidin-biotin complex in an ELISA system: a quantitative comparison with two other immunoperoxidase detection systems using keratin antisera.
Madri J, Barwick K. Use of avidin-biotin complex in an ELISA system: a quantitative comparison with two other immunoperoxidase detection systems using keratin antisera. Laboratory Investigation 1983, 48: 98-107. PMID: 6185760.Peer-Reviewed Original ResearchMeSH KeywordsAntibodiesAvidinBiotinCarcinoma, Squamous CellChemical PhenomenaChemistryEnzyme-Linked Immunosorbent AssayHumansImmunoenzyme TechniquesIsoenzymesKeratinsLung NeoplasmsPeroxidasePeroxidases
1982
An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin.
Barwick K, Madri J. An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin. Laboratory Investigation 1982, 47: 276-80. PMID: 6180248.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaAdultAntibodiesEnzyme-Linked Immunosorbent AssayFactor VIIIFemaleHorseradish PeroxidaseHumansImmunoenzyme TechniquesKeratinsMaleMiddle AgedConceptsAdenomatoid tumorMesothelial originAntigen antibodiesKeratin antibodiesFactor VIII antibodiesImmunohistochemical studyAdenoid cellsVIII antibodiesAdenoid structuresEndothelial originFactor VIIIParaffin blocksTumorsCases tissueAntibodiesHistochemical dataAntibody probesImmunoelectron microscopyAdditional evidenceCellsAntigenKeratinAn immunohistochemical study of nasopharyngeal neoplasms using keratin antibodies
Madri J, Barwick K. An immunohistochemical study of nasopharyngeal neoplasms using keratin antibodies. The American Journal Of Surgical Pathology 1982, 6: 143-150. PMID: 6179429, DOI: 10.1097/00000478-198203000-00006.Peer-Reviewed Original ResearchMeSH KeywordsAntibodiesCarcinomaCarcinoma, Squamous CellEnzyme-Linked Immunosorbent AssayHumansImmunoenzyme TechniquesKeratinsNasopharyngeal NeoplasmsConceptsKeratin antibodiesNasopharyngeal neoplasmsSquamous cell carcinomaUsual staining methodsCell carcinomaMesenchymal tumorsImmunohistochemical studyImmunohistochemical meansAccurate diagnosisAntibodiesNeoplasmsTumorsStaining methodKeratin proteinsNonkeratinizingCarcinomaNasopharynxNeoplasiaSensitive methodDiagnosis